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Rare variants in high-risk autism gene can alter architecture and organization of neurons, study finds

Scientists at the University of North Carolina at Chapel Hill School of Medicine and colleagues have demonstrated that rare variants in the ANK2 gene, consistently found in individuals with autism spectrum disorder (ASD), can alter architecture and organization of neurons, potentially contributing to autism and neurodevelopmental comorbidities.

29 Nov 2021

Tomosyn protein's key contribution to heterogeneity of neurons revealed

The versatility of the nervous system comes from not only the diversity of ways in which neurons communicate in circuits, but also their "plasticity," or ability to change those connections when new information has to be remembered, when their circuit partners change, or other conditions emerge.

29 Nov 2021

Context-dependent, untangled persistency facilitates value signal coding across the brain

In 2019 University of California San Diego researchers discovered the area of the brain where "value decisions" are made.

24 Nov 2021

SARS-CoV-2 moves between permissive cells and non-permissive neuronal cells via tunneling nanotubes (TNT)

Scientists investigate the neuroinvasive potential of SARS-CoV-2 and the role of tunneling nanotubes (TNTs) in spreading the infection to neighboring cells.

23 Nov 2021

Semiflexible optoelectrodes for high-resolution neuron readout and stimulation with low damage

The use of electrodes placed inside the brains of laboratory specimens has pushed the field of neuroscience to new findings for decades.

23 Nov 2021

New combination of drugs could break down harmful protein aggregates in Parkinson's disease

A new combination of drugs could fix the broken lysosomal enzyme pathway in Parkinson's disease-afflicted brain cells, according to a Northwestern Medicine study published in Neuron.

23 Nov 2021

Study shows SARS-CoV-2 can infect and replicate in human iPSC-derived neurons

In a study recently published on the bioRxiv preprint server, researchers attempted to further increase the scope of previous studies in examining SARS-CoV-2 infection of human CNS resident cells.

22 Nov 2021

Scientists can read the brain activity of tiny worm to predict smells

It sounds like a party trick: scientists can now look at the brain activity of a tiny worm and tell you which chemical the animal smelled a few seconds before.

21 Nov 2021

Researchers use embryonic stem cell model to study genetic architecture in the hypothalamus

A study led by researchers at Children's Hospital of Philadelphia has implicated several genes involved in a variety of bodily functions associated with the hypothalamus, a notoriously difficult-to-study region of the brain.

21 Nov 2021

Repurposed ALS drug could slow gradual brain cell loss in Niemann-Pick disease type C1

Riluzole, a drug approved to treat amyotrophic lateral sclerosis (ALS), a disease affecting nerve cells controlling movement, could slow the gradual loss of a particular brain cell that occurs in Niemann-Pick disease type C1 (NPC1), a rare genetic disorder affecting children and adolescents, suggests a study in mice by scientists at the National Institutes of Health.

20 Nov 2021

Study uncovers the herpes virus' strategy for infecting the nervous system

Herpes type 1 is sealed with a kiss for a lifetime. More than half of U.S. adults are carriers of HSV1 (herpes simplex virus type 1) which hibernates in the peripheral nervous system and can never be eradicated.

17 Nov 2021

Researchers shed light on how brain cells ‘navigate’ during the day and night

To navigate successfully in an environment, you need to continuously track the speed and direction of your head, even in the dark.

16 Nov 2021

Tighter blood pressure management may lead to better spinal cord injury recovery

Patients with new spinal cord injuries whose blood pressure is maintained within a newly defined range during surgery may stand a better chance of regaining some mobility and functionality – even in patients with the most devastating injuries – according to a new study by researchers at UC San Francisco.

16 Nov 2021

ALS also causes retinal alterations, study reveals

Amyotrophic lateral sclerosis (ALS), characterized by harm to brain neurons and to the spinal cord, also affects the tissue of the retina, according to a study headed up by Universidad Complutense de Madrid.

16 Nov 2021

Scientists develop a promising new approach to potentially treat Alzheimer's disease

A promising new approach to potentially treat Alzheimer's disease – and also vaccinate against it – has been developed by a team of UK and German scientists.

15 Nov 2021

Study reveals surprising new information about how the brain is affected by salt consumption

A first-of-its-kind study led by researchers at Georgia State reveals surprising new information about the relationship between neuron activity and blood flow deep in the brain, as well as how the brain is affected by salt consumption.

11 Nov 2021

UArizona researchers get closer to developing a safe, effective non-opioid pain reliever

Researchers at the University of Arizona Health Sciences are closer to developing a safe and effective non-opioid pain reliever after a study showed that a new compound they created reduces the sensation of pain by regulating a biological channel linked to pain.

10 Nov 2021

Identifying an important protein for motor coordination

News-Medical speaks to Professor Jorge Ruas about how he has identified an important protein involved in motor coordination.

10 Nov 2021

Research opens the door to new therapeutic options for Parkinson's disease

These advances have been reported in a new scientific article published in the international journal Nature, fruit of the collaboration between Northwestern University (Chicago), Weill Cornell Medical College (New York) and the Institute of Biomedicine of Seville HUVR/CSIC/US/ and Ciberned.

8 Nov 2021

Study reveals the role of SPOP protein in an inherited form of ALS

The damaging effects of toxic proteins created in one inherited form of amyotrophic lateral sclerosis (ALS) are mediated by a protein called SPOP, according to a study published in the Proceedings of the National Academy of the Sciences.

8 Nov 2021

Neuron News and Research

Rare variants in high-risk autism gene can alter architecture and organization of neurons, study finds

Tomosyn protein's key contribution to heterogeneity of neurons revealed

Context-dependent, untangled persistency facilitates value signal coding across the brain

SARS-CoV-2 moves between permissive cells and non-permissive neuronal cells via tunneling nanotubes (TNT)

Semiflexible optoelectrodes for high-resolution neuron readout and stimulation with low damage

New combination of drugs could break down harmful protein aggregates in Parkinson's disease

Study shows SARS-CoV-2 can infect and replicate in human iPSC-derived neurons

Scientists can read the brain activity of tiny worm to predict smells

Researchers use embryonic stem cell model to study genetic architecture in the hypothalamus

Repurposed ALS drug could slow gradual brain cell loss in Niemann-Pick disease type C1

Study uncovers the herpes virus' strategy for infecting the nervous system

Researchers shed light on how brain cells ‘navigate’ during the day and night

Tighter blood pressure management may lead to better spinal cord injury recovery

ALS also causes retinal alterations, study reveals

Scientists develop a promising new approach to potentially treat Alzheimer's disease

Study reveals surprising new information about how the brain is affected by salt consumption

UArizona researchers get closer to developing a safe, effective non-opioid pain reliever

Identifying an important protein for motor coordination

Research opens the door to new therapeutic options for Parkinson's disease

Study reveals the role of SPOP protein in an inherited form of ALS

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