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Penn receives $8 million grant from NCI to study effects of PDT

Researchers at the Perelman School of Medicine at the University of Pennsylvania in collaboration with the Roswell Park Cancer Institute have received an $8 million grant from the National Cancer Institute (NCI) to study the effects of photodynamic light therapy (PDT) in patients with malignant pleural mesothelioma, a rare, aggressive and deadly cancer that most often manifests itself in the lining of the lungs and is caused almost exclusively by exposure to asbestos.

10 Jul 2014

Immune marker predicts infection risk in critically ill children with traumatic injuries

Researchers studying critically ill children with traumatic injuries have identified an immune marker that predicts which patients are likely to develop a hospital-acquired infection.

10 Jul 2014

NIAID launches CRS3123 Phase I trial to treat C. difficile infection

The National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health, has launched an early-stage clinical trial of CRS3123, an investigational oral antibiotic intended to treat Clostridium difficile (C. difficile) infection.

10 Jul 2014

NIH funds Phase II 90-subject pediatric clinical trial at UCLA

NeuroSigma, Inc., a California-based life sciences company focused on commercialization of its non-invasive Monarch eTNS System for the treatment of neurological and neuropsychiatric disorders, today announced that the U.S. National Institutes of Health (NIH) has awarded UCLA a grant that funds a Phase II 90-subject pediatric clinical trial at the University of California, Los Angeles focused on the treatment of Attention Deficit Hyperactivity Disorder (ADHD) with NeuroSigma's external trigeminal nerve stimulation (eTNS) System.

10 Jul 2014

Researchers receive $8 million NCI grant to study effects of PDT in patients with mesothelioma

Researchers at the Perelman School of Medicine at the University of Pennsylvania in collaboration with the Roswell Park Cancer Institute have received an $8 million grant from the National Cancer Institute to study the effects of photodynamic light therapy (PDT) in patients with malignant pleural mesothelioma, a rare, aggressive and deadly cancer that most often manifests itself in the lining of the lungs and is caused almost exclusively by exposure to asbestos.

10 Jul 2014

PTC Therapeutics initiates reimbursed expanded access program for Translarna

PTC Therapeutics, Inc. today announced the initiation of a reimbursed expanded access program (EAP). PTC's EAP program is intended to make Translarna (ataluren) available to patients before commercial availability in certain countries.

9 Jul 2014

Integrated therapies can reduce depression by half among people with low vision due to AMD

The first clinical trial to examine integrated low vision and mental health treatment has shown that the approach can reduce the incidence of depression by half among people with low vision due to age-related macular degeneration (AMD).

9 Jul 2014

Bowel cancer patients with high levels of vitamin D are more likely to survive the disease

Bowel cancer patients with high levels of vitamin D in their blood are more likely to survive the disease, a study shows.

9 Jul 2014

Antibiotic treatment for patients who underwent gall bladder removal does not reduce infection risk

Among patients who underwent gall bladder removal for acute calculous cholecystitis, lack of postoperative antibiotic treatment did not result in a greater incidence of infections, according to a study in the July 9 issue of JAMA.

9 Jul 2014

UCLA project receives $15M to restore lost memory functions in brain-injured people

The UCLA Program in Memory Restoration has been awarded up to $15 million by the Defense Advanced Research Projects Agency (DARPA) for a four -year project aiming to help brain-injured people restore lost memory functions.

9 Jul 2014

Children who received home visits from nurses are less likely to die from preventable causes

Low-income mothers and their first-born children who received home visits from nurses were less likely to die from preventable causes during a two-decade period studied by a University of Colorado School of Medicine professor, according to a report published in JAMA Pediatrics - a leading, peer-reviewed journal of the American Medical Association.

8 Jul 2014

Study: Behavioral weight loss can help manage menopausal hot flashes

Now women have yet one more incentive to lose weight as a new study has shown evidence that behavioral weight loss can help manage menopausal hot flashes.

8 Jul 2014

New test for TB could improve speed and accuracy of diagnosis for deadliest diseases

A new test for tuberculosis (TB) could dramatically improve the speed and accuracy of diagnosis for one of the world's deadliest diseases, enabling health care providers to report results to patients within minutes, according to a study published this week in the journal Angewandte Chemie.

8 Jul 2014

$FDA grants Breakthrough Therapy status to Novartis' CTL019 for treatment of relapsed/refractory ALL$

FDA grants Breakthrough Therapy status to Novartis' CTL019 for treatment of relapsed/refractory ALL

Novartis announced today that the United States Food and Drug Administration has granted Breakthrough Therapy status to CTL019, an investigational chimeric antigen receptor (CAR) therapy for the treatment of pediatric and adult patients with relapsed/refractory acute lymphoblastic leukemia (r/r ALL).

7 Jul 2014

Grunenthal Group submits Marketing Authorization Application to EMA for ZALVISO

AcelRx Pharmaceuticals, Inc. and Grunenthal Group announced today that Grunenthal has submitted a Marketing Authorization Application (MAA) to the European Medicines Authority for ZALVISO for the management of moderate to severe acute pain in adult patients in a medically supervised environment.

7 Jul 2014

Poor nutrition, health cause disparities in fetal growth and newborn size worldwide

Babies' growth in the womb and their size at birth, especially their length, are strikingly similar the world over - when babies are born to healthy, well-educated and well-nourished mothers.

7 Jul 2014

OHSU professor recognized with AAAS Martin and Rose Wachtel Cancer Research Award

Jeffrey Tyner, Ph.D., assistant professor of Cell, Developmental & Cancer Biology for Oregon Health & Science University (OHSU) and a researcher with OHSU's Knight Cancer Institute, has won a distinguished award from the American Association for the Advancement of Science (AAAS) for the development of a research program that more rapidly identifies the mutations driving a patient's cancer and accelerates development of precision treatments.

4 Jul 2014

Multicenter trial aims to find safety, effectiveness of probiotics in infants with stomach flu

Consumers worldwide spend billions of dollars each year on probiotic foods and supplements. But studies evaluating probiotics - microorganisms believed to aid digestive health - have been limited.

4 Jul 2014

Scientists produce drug compound with potential to block HIV transmission in women

Scientists at the University of Nebraska-Lincoln College of Engineering's Biological Process Development Facility have successfully produced a drug compound with potential to block HIV transmission in women.

4 Jul 2014

UCB, Dermira enter into licensing agreement for development, commercialization of Cimzia

UCB, a global biopharmaceutical leader, and Dermira, Inc., a privately held US-based dermatology company, announced today that they have entered into an exclusive licensing agreement for the development and future commercialization of Cimzia (certolizumab pegol) in dermatology.

3 Jul 2014

Clinical Trial News and Research

Penn receives $8 million grant from NCI to study effects of PDT

Immune marker predicts infection risk in critically ill children with traumatic injuries

NIAID launches CRS3123 Phase I trial to treat C. difficile infection

NIH funds Phase II 90-subject pediatric clinical trial at UCLA

Researchers receive $8 million NCI grant to study effects of PDT in patients with mesothelioma

PTC Therapeutics initiates reimbursed expanded access program for Translarna

Integrated therapies can reduce depression by half among people with low vision due to AMD

Bowel cancer patients with high levels of vitamin D are more likely to survive the disease

Antibiotic treatment for patients who underwent gall bladder removal does not reduce infection risk

UCLA project receives $15M to restore lost memory functions in brain-injured people

Children who received home visits from nurses are less likely to die from preventable causes

Study: Behavioral weight loss can help manage menopausal hot flashes

New test for TB could improve speed and accuracy of diagnosis for deadliest diseases

FDA grants Breakthrough Therapy status to Novartis' CTL019 for treatment of relapsed/refractory ALL

Grunenthal Group submits Marketing Authorization Application to EMA for ZALVISO

Poor nutrition, health cause disparities in fetal growth and newborn size worldwide

OHSU professor recognized with AAAS Martin and Rose Wachtel Cancer Research Award

Multicenter trial aims to find safety, effectiveness of probiotics in infants with stomach flu

Scientists produce drug compound with potential to block HIV transmission in women

UCB, Dermira enter into licensing agreement for development, commercialization of Cimzia

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