Efficacy News and Research

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Transvenous lead extraction in low volume centre linked to doubled risk of death

Cardiac lead extraction is safer in high volume centres, according to the largest study of contemporary practice in Europe published today in European Heart Journal. Extraction in a low volume centre was associated with a doubled risk of death while in hospital.

23 Mar 2017

Scientists identify molecule that could be targeted to prevent vision loss in diabetics and preterm infants

Researchers at Bascom Palmer Eye Institute, part of the University of Miami Miller School of Medicine, have identified a new molecule that induces the formation of abnormal blood vessels in the eyes of diabetic mice.

23 Mar 2017

NIDA grant offers support to develop couples-based drug use intervention for partnered gay men

Dr. Tyrel Starks, an Assistant Professor of Psychology at Hunter College and the Graduate Center of the City University of New York, and faculty affiliate of the Hunter College Center for HIV/AIDS Educational Studies and Training, has been awarded a three-year grant from the National Institute of Drug Abuse, totaling $666,900, to develop a couples-based drug use intervention for gay male couples.

22 Mar 2017

Study shows efficacy of biologics for mucosal healing in Crohn's disease and ulcerative colitis

Although anti-inflammatory treatments are quite effective at reducing symptoms in patients with Crohn's disease and ulcerative colitis, the mucosal lining of the intestine often remains ulcerated, and many patients still ultimately require surgery.

22 Mar 2017

FDA approves drug as add-on treatment for Parkinson's disease patients

The U.S. Food and Drug Administration today approved Xadago (safinamide) tablets as an add-on treatment for patients with Parkinson's disease who are currently taking levodopa/carbidopa and experiencing "off" episodes.

21 Mar 2017

Efficacy of innovative gene therapy can be tested quickly and cost-effectively using new cellular model

Using a new cellular model, innovative gene therapy approaches for the hereditary immunodeficiency Chronic Granulomatous Disease can be tested faster and cost-effectively in the lab for their efficacy.

21 Mar 2017

Treatment with interferon may ease symptoms of Ebola patients

A pilot study of a class of drugs used to treat hepatitis and some forms of multiple sclerosis has been shown for the first time to ease symptoms of Ebola patients, while also increasing their survival.

21 Mar 2017

Research findings hold promise to generate blood cell precursors from hPSCs

The Galat laboratory at Stanley Manne Children's Research Institute, Ann & Robert H. Lurie Children's Hospital of Chicago, has developed an elegant system to derive blood cell precursors from human pluripotent stem cells (hPSC).

21 Mar 2017

Smartphones can help parents, caregivers to improve health outcomes for kids, research shows

A new, wide-ranging review of available research shows parents and caregivers can improve health outcomes for kids by using mobile-phone apps and text messaging.

20 Mar 2017

Clinical study tests efficacy of new focused ultrasound-based treatment for breast fibroadenoma

Patients with benign breast tumors may be eligible for a new focused ultrasound-based investigational treatment as part of a pivotal, multi-center clinical study. The trial began last month at the University of Virginia Medical Center.

20 Mar 2017

Uninterrupted use of new anticoagulant reduces major bleeding events during atrial fibrillation ablation

Uninterrupted treatment with dabigatran, a non-vitamin K antagonist oral anticoagulant (NOACs), before, during and after ablation to treat atrial fibrillation significantly reduced the incidence of major bleeding events compared with uninterrupted use of the more established anticoagulant warfarin, according to research presented at the American College of Cardiology's 66th Annual Scientific Session.

20 Mar 2017

Closing left atrial appendage linked to reduction in stroke risk for AFib patients

For patients with atrial fibrillation (AFib), a common heart rhythm disorder, closing the area of the heart known as the left atrial appendage as an add-on procedure during cardiac surgery was associated with a 40 percent reduction in the risk of thromboembolism (a condition when a blood clot forms and blocks an artery, which can cause a stroke or other complications) according to an observational study presented at the American College of Cardiology's 66th Annual Scientific Session.

20 Mar 2017

Combination approach holds potential for treating lung cancer patients

An emerging approach for cancer treatment seeks to combine radiation therapy with immune checkpoint inhibitors to more effectively control tumors in the chest with an acceptable risk of severe treatment-related side effects.

17 Mar 2017

Clinical study to examine whether antibiotics can be safe, effective alternative to appendectomy

For 130 years, surgery has been the standard treatment for appendicitis — inflammation of the appendix, a short tube extending from the colon.

17 Mar 2017

Northumbria University uses G:BOX Chemi XX6 multi-application imager in biomedical research

Syngene, a world-leading manufacturer of image analysis solutions, today announced its G:BOX Chemi XX6 is being used by scientists at Northumbria University for imaging chemiluminescent enzymes and other proteins on Western blots. This is contributing to rapidly providing researchers with accurate information on changes in protein in chronic conditions such as diabetes, heart disease and cancer.

From Syngene 17 Mar 2017

Mount Sinai researchers review progress made in using ketamine and other therapies to treat depression

Major depressive disorder (MDD) impacts 15 million Americans and is the leading cause of disability, yet current treatments possess limited efficacy.

17 Mar 2017

Roswell Park-led study shows benefits of ‘one and done’ SBRT treatment approach for NSCLC patients

New research led by a radiation oncologist at Roswell Park Cancer Institute indicates that less may be more when it comes to some forms of radiation therapy for cancer.

17 Mar 2017

Exact replication studies may accelerate development of better cancer treatments

In response to rising concern that many published scientific results may be false, the Reproducibility Project: Cancer Biology set out to replicate findings from the 50 most cited cancer studies from 2010-2012.

15 Mar 2017

Study warns against use of bone morphogenetic proteins in pediatric spinal fusion

Bone morphogenetic proteins, commonly used off-label to enhance pediatric spinal fusion (spinal arthrodesis), did not improve revision rates for pediatric spinal fusion, according to a study presented on March 14 at the American Academy of Orthopaedic Surgeons Annual Meeting in San Diego.

15 Mar 2017

Florida Hospital Nicholson Center completes research projects on robotic surgery using $5.9 million DOD grants

The Florida Hospital Nicholson Center today announces the completion of 13 research projects using $5.9 million in grants from the Department of Defense over the last six years, all focused on advancing robotic and laparoscopic surgery safety and creating a new standard for surgical training.

15 Mar 2017

Efficacy News and Research

Transvenous lead extraction in low volume centre linked to doubled risk of death

Scientists identify molecule that could be targeted to prevent vision loss in diabetics and preterm infants

NIDA grant offers support to develop couples-based drug use intervention for partnered gay men

Study shows efficacy of biologics for mucosal healing in Crohn's disease and ulcerative colitis

FDA approves drug as add-on treatment for Parkinson's disease patients

Efficacy of innovative gene therapy can be tested quickly and cost-effectively using new cellular model

Treatment with interferon may ease symptoms of Ebola patients

Research findings hold promise to generate blood cell precursors from hPSCs

Smartphones can help parents, caregivers to improve health outcomes for kids, research shows

Clinical study tests efficacy of new focused ultrasound-based treatment for breast fibroadenoma

Uninterrupted use of new anticoagulant reduces major bleeding events during atrial fibrillation ablation

Closing left atrial appendage linked to reduction in stroke risk for AFib patients

Combination approach holds potential for treating lung cancer patients

Clinical study to examine whether antibiotics can be safe, effective alternative to appendectomy

Northumbria University uses G:BOX Chemi XX6 multi-application imager in biomedical research

Mount Sinai researchers review progress made in using ketamine and other therapies to treat depression

Roswell Park-led study shows benefits of ‘one and done’ SBRT treatment approach for NSCLC patients

Exact replication studies may accelerate development of better cancer treatments

Study warns against use of bone morphogenetic proteins in pediatric spinal fusion

Florida Hospital Nicholson Center completes research projects on robotic surgery using $5.9 million DOD grants

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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