Clinical Trial News and Research

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CNS stimulant no more effective than placebo for alleviating lung cancer fatigue

Patients with advanced non-small-cell lung cancer who received the central nervous system stimulant modafinil reported no greater reduction in fatigue than patients given placebo, show study results.

13 May 2014

Da Volterra presents promising results of DAV-132 compound for prevention of severe C. diff infections

Da Volterra, a leading biopharmaceutical company in the field of bacterial resistance, announces today very promising new results about DAV132 in the prevention of the side effects of antibiotics and the occurrence of severe Clostridium difficile infections.

13 May 2014

New study presents novel strategy for treating multiple myeloma

A new study by researchers at The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC - James) provides evidence that genetically modifying immune cells might effectively treat multiple myeloma, a disease that remains incurable and will account for an estimated 24,000 new cases and 11,100 deaths in 2014

13 May 2014

University of Chicago receives $3.9M award to serve as Lead Academic Participating Site for NCTN

A team from the University of Chicago Medicine Comprehensive Cancer Center has received a five-year, $3.9-million award from the National Cancer Institute to serve as a Lead Academic Participating Site for the newly created National Clinical Trials Network (NCTN).

13 May 2014

Beaumont Children's Hospital wins grant from CureSearch Children's Cancer to help fund therapeutic clinical trials

CureSearch for Children's Cancer has awarded a $20,000 grant to Beaumont Children's Hospital to help fund therapeutic clinical trials.

13 May 2014

Leadless pacemaker technology shows promising performance after 12 months

Vivek Reddy, MD, Director of Arrhythmia Services for The Mount Sinai Hospital, reported his promising12-month follow-up data showing the world's first leadless pacemaker is demonstrating overall device performance comparable to conventional pacemakers. Dr. Reddy presented the one-year LEADLESS study data findings during his late-breaking clinical trial presentation on May 9 at Heart Rhythm 2014, the Heart Rhythm Society's 35th Annual Scientific Sessions in San Francisco, CA.

12 May 2014

Akebia Therapeutics reports net loss of $9.7 million for Q1 2014

Akebia Therapeutics, Inc., a biopharmaceutical company focused on the development of novel, proprietary therapeutics based on hypoxia-inducible factor (HIF) biology and the commercialization of these products for patients with kidney disease, today announced financial results for the first quarter ended March 31, 2014.

12 May 2014

Foundation Medicine obtains CE mark for FoundationOne

Foundation Medicine, Inc. today announced that it has obtained a CE mark for FoundationOne®. The CE mark allows FoundationOne to be placed on the market in the European Economic Area.

12 May 2014

Verastem announces expansion of ongoing COMMAND study in Japan

Verastem, Inc., focused on discovering and developing drugs to treat cancer by the targeted killing of cancer stem cells, today announced the expansion of its ongoing COMMAND study to include clinical trial sites in Japan.

12 May 2014

Pfizer reports positive results from rLP2086 Phase 2 study for invasive meningococcal disease

Pfizer Inc. announced today the results from two Phase 2 studies of bivalent rLP2086, Pfizer's recombinant vaccine candidate, currently under development for the prevention of invasive meningococcal disease caused by Neisseria meningitidis serogroup B in 10 to 25 year olds.

12 May 2014

Flatiron Health agrees to acquire Altos Solutions

Altos Solutions, creators of OncoEMR, the first web-based oncology-specific electronic medical record, today announced an agreement to be acquired by Flatiron Health.

9 May 2014

Patients with Parkinson's disease show improvements after exenatide therapy

Follow-Up Study Published in the Journal of Parkinson's Disease Supports an Earlier "Proof of Concept" Trial. A follow-up study of patients with Parkinson's disease (PD) who participated in an earlier "proof of concept" clinical trial using exenatide showed that improvements persisted twelve months after discontinuing exenatide therapy.

9 May 2014

Wake Forest Baptist Medical Center finds novel treatment to keep lung cancer at bay

An old idea of retreating lung tumors with radiation is new again, especially with the technological advances seen in radiation oncology over the last decade.

9 May 2014

Mice study shows specific energy source responsible for performing complex cognitive functions

New research suggests that certain types of brain cells may be "picky eaters," seeming to prefer one specific energy source over others.

9 May 2014

Neurovance reports positive results from EB-1020 SR phase 2a pilot study in adult ADHD patients

Neurovance, Inc. today announced complete results from its phase 2a pilot study of EB-1020 SR, a non-stimulant, in adult male patients with all subtypes of ADHD (attention deficit hyperactivity disorder).

8 May 2014

Finding has implications for understanding cognitive decline in degenerative diseases

New research suggests that certain types of brain cells may be "picky eaters," seeming to prefer one specific energy source over others. The finding has implications for understanding the cognitive decline seen in aging and degenerative diseases such as Alzheimer's and multiple sclerosis.

8 May 2014

IPM gains exclusive worldwide rights to promising HIV prevention medicine from Janssen R&D Ireland

The International Partnership for Microbicides announced today that it has received exclusive worldwide rights to a promising HIV prevention medicine called dapivirine from Janssen R&D Ireland, one of the Janssen Pharmaceutical Companies of Johnson & Johnson.

8 May 2014

MRI-guided focused ultrasound to treat pain from bone metastases

InSightec Ltd, the leader in magnetic resonance imaging guided Focused Ultrasound therapy (MRgFUS), announced that the results of its ExAblate® Phase III clinical trial for treating painful bone metastases have been published online in the JNCI, Journal of National Cancer Institute.

8 May 2014

WHI: Combined hormone therapy clinical trial yields massive economic return

Economic findings were released today on the Women's Health Initiative (WHI), estrogen plus progestin (E+P) trial.

8 May 2014

First international molecular screening program at IMPAKT for metastatic breast cancer

While research has made great strides in recent decades to improve and significantly extend the lives of patients with early breast cancer, the needs of patients with advanced or metastatic disease have largely been ignored.

8 May 2014

Clinical Trial News and Research

CNS stimulant no more effective than placebo for alleviating lung cancer fatigue

Da Volterra presents promising results of DAV-132 compound for prevention of severe C. diff infections

New study presents novel strategy for treating multiple myeloma

University of Chicago receives $3.9M award to serve as Lead Academic Participating Site for NCTN

Beaumont Children's Hospital wins grant from CureSearch Children's Cancer to help fund therapeutic clinical trials

Leadless pacemaker technology shows promising performance after 12 months

Akebia Therapeutics reports net loss of $9.7 million for Q1 2014

Foundation Medicine obtains CE mark for FoundationOne

Verastem announces expansion of ongoing COMMAND study in Japan

Pfizer reports positive results from rLP2086 Phase 2 study for invasive meningococcal disease

Flatiron Health agrees to acquire Altos Solutions

Patients with Parkinson's disease show improvements after exenatide therapy

Wake Forest Baptist Medical Center finds novel treatment to keep lung cancer at bay

Mice study shows specific energy source responsible for performing complex cognitive functions

Neurovance reports positive results from EB-1020 SR phase 2a pilot study in adult ADHD patients

Finding has implications for understanding cognitive decline in degenerative diseases

IPM gains exclusive worldwide rights to promising HIV prevention medicine from Janssen R&D Ireland

MRI-guided focused ultrasound to treat pain from bone metastases

WHI: Combined hormone therapy clinical trial yields massive economic return

First international molecular screening program at IMPAKT for metastatic breast cancer

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