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Rheumatoid arthritis drug blocks metabolic pathway, reduces breast cancer tumors in mice

Mount Sinai researchers have discovered that a rheumatoid arthritis drug can block a metabolic pathway that occurs in tumors with a common cancer-causing gene mutation, offering a new possible therapy for aggressive cancers with few therapeutic options, according to a study to be published in Cancer Discovery.

3 Mar 2017

Study explores women's experiences, perceptions of shared decision-making for breast cancer treatment

Most women want to be involved in shared decision-making with oncologists when faced with treatment decisions for breast cancer, a new study from Leeds Beckett University has found.

2 Mar 2017

Study shows new drug as promising treatment option for difficult-to-treat rheumatoid arthritis patients

Between 3 and 5% of the population suffer from a form of inflammatory rheumatism. It affects approximately 250,000 - 400,000 people in Austria.

2 Mar 2017

Brown fat in humans three times greater than previously known, TUM study shows

Compared to white fat, brown body fat burns through energy at an extraordinary rate. However, until now the proportion of brown fat in humans was thought to be quite small.

1 Mar 2017

Study highlights need to control doping problem in amateur sports

A study led by the University of Granada has shown that doping is not only a problem exclusive to professional sports, but also occurs in amateur sports.

1 Mar 2017

Two migration proteins increase predictive ability of biomarker for pancreatic cancer

Adding two blood-borne proteins associated with cancer cell migration increases the predictive ability of the current biomarker for pancreatic cancer to detect early stage disease, a research team from The University of Texas MD Anderson Cancer Center reports in the Journal of the National Cancer Institute.

1 Mar 2017

UNC Lineberger achieves major milestone with launch of cellular immunotherapy program

University of North Carolina Lineberger Comprehensive Cancer Center researchers have achieved a major milestone with the launch of two clinical trials testing an experimental therapy in which patients' own immune cells are genetically engineered to fight their cancer.

1 Mar 2017

UC scientists discover new strategy to personalize blood, brain cancer therapy

Researchers at the University of Cincinnati College of Medicine have discovered a new potential strategy to personalize therapy for brain and blood cancers.

1 Mar 2017

Danish researchers get closer to finding treatment for malignant cerebral tumour in children

DIPG (Diffuse Intrinsic Pontine Glioma) is a rare malignant cerebral tumour in children. It has only a 1% 5-year survival rate, amongst other things because it is not possible to operate because the tumour is located in the brain stem.

28 Feb 2017

Scientists identify potential therapeutic target for aggressive lymphomas

Scientists at the Centro Nacional de Investigaciones Cardiovasculares Carlos III have identified a possible therapeutic target for 2 types of very aggressive lymphomas.

28 Feb 2017

Biologists develop new way to inhibit cancer cell cleanup mechanism

The genomes of cancer cells--cells that do not obey signals to stop reproducing--are riddled with genetic mutations, causing them inadvertently to make many dysfunctional proteins.

28 Feb 2017

Two thirds of IPF patients report being involved during the decision-making process for the most appropriate treatment

New results from a global survey of over 150 people living with idiopathic pulmonary fibrosis (IPF), a life-threatening rare lung disease, demonstrate that while many patients were involved in treatment decisions, opportunities exist to improve the level of dialogue between patients and healthcare professionals.

28 Feb 2017

GUMC launches phase II clinical study to examine safety of cancer drug for Parkinson's disease

Georgetown University Medical Center today announces the launch of a phase II clinical trial to study the safety of the cancer drug nilotinib and its effects on clinical outcomes and biomarkers in people with Parkinson's disease.

27 Feb 2017

Researchers discover promising target for treatment of leishmaniasis

Each year, about 2 million people contract leishmaniasis, a parasitic disease transmitted by the bite of a sand fly. The cutaneous form of the disease results in disfiguring skin ulcers that may take months or years to heal and in rare cases can become metastatic, causing major tissue damage.

24 Feb 2017

Scientists devise novel DNA vaccine approach against important cancer antigen targets

Scientists at The Wistar Institute and Inovio Pharmaceuticals, Inc. have devised a novel DNA vaccine approach through molecular design to improve the immune responses elicited against one of the most important cancer antigen targets. Study results were published in the journal Molecular Therapy.

24 Feb 2017

HIV-infected individuals with kidney failure less likely to receive necessary transplant, study finds

A new study finds that HIV-infected individuals with kidney failure are less likely to receive a kidney transplant—especially from living donors—than their uninfected counterparts.

24 Feb 2017

Discovery of dual role played by PGK1 enzyme may indicate new therapeutic target for brain cancer

Discovery of a dual role played by the enzyme phosphoglycerate kinase 1 (PGK1) may indicate a new therapeutic target for glioblastoma, an often fatal form of brain cancer, according to researchers at The University of Texas MD Anderson Cancer Center.

24 Feb 2017

Researchers develop new tool that quickly reveals metabolic fluxes in cells

If we were to take photographs at the underground stations in Barcelona, we would see the number of people waiting, find out what time the rush hour takes place and deduce why some stations are busier than others.

23 Feb 2017

New compounds with potent anticancer activity could lessen side effects of oncological treatments

The Universitat Jaume I, the Spanish Centre for Advanced Scientific Research and the University of Pavia have patented new compounds with potent anticancer activity in breast and colon tumour cell lines that have low toxicity in healthy cells, which can dramatically decrease side effects during chemotherapy treatment.

23 Feb 2017

UC San Diego researchers suggest transplanting good bacteria to treat patients with atopic dermatitis

Healthy human skin is alive with bacteria. In fact, there are more microorganisms living in and on the human body than there are human cells. Most can live on the human skin without harming the host, but in some people bacteria can negatively alter their health, maybe even become life-threatening.

23 Feb 2017

Efficacy News and Research

Rheumatoid arthritis drug blocks metabolic pathway, reduces breast cancer tumors in mice

Study explores women's experiences, perceptions of shared decision-making for breast cancer treatment

Study shows new drug as promising treatment option for difficult-to-treat rheumatoid arthritis patients

Brown fat in humans three times greater than previously known, TUM study shows

Study highlights need to control doping problem in amateur sports

Two migration proteins increase predictive ability of biomarker for pancreatic cancer

UNC Lineberger achieves major milestone with launch of cellular immunotherapy program

UC scientists discover new strategy to personalize blood, brain cancer therapy

Danish researchers get closer to finding treatment for malignant cerebral tumour in children

Scientists identify potential therapeutic target for aggressive lymphomas

Biologists develop new way to inhibit cancer cell cleanup mechanism

Two thirds of IPF patients report being involved during the decision-making process for the most appropriate treatment

GUMC launches phase II clinical study to examine safety of cancer drug for Parkinson's disease

Researchers discover promising target for treatment of leishmaniasis

Scientists devise novel DNA vaccine approach against important cancer antigen targets

HIV-infected individuals with kidney failure less likely to receive necessary transplant, study finds

Discovery of dual role played by PGK1 enzyme may indicate new therapeutic target for brain cancer

Researchers develop new tool that quickly reveals metabolic fluxes in cells

New compounds with potent anticancer activity could lessen side effects of oncological treatments

UC San Diego researchers suggest transplanting good bacteria to treat patients with atopic dermatitis

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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