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Proteins are complex molecules that are made up of amino acids. They can be found in every cell in the body, and carry out vital processes that keep human beings alive. Mutations in proteins can lead to a multitude of diseases, the most common being cancer.

A novel mouse model to test SARS-CoV-2 viral infection

In a recent study posted to the Research Square* preprint server, researchers developed a novel mouse model for testing infection by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2).

26 Apr 2022

Scientists discover how SARS-CoV-2 activates platelets

In a recent study published in the Blood Advances journal, the researchers assessed the impact of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on platelet activation.

25 Apr 2022

Increased power and amplitude of memory B cells after SARS-CoV-2 mRNA booster

In a recent study published in the journal Nature, the researchers investigated the impact of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) booster vaccine on memory B cells.

25 Apr 2022

Scientists show how T cells may help protect against severe COVID

In a recent study published in the Clinical Infectious Diseases journal, the researchers summarized the perspectives and observations on severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-related adaptive immunity.

25 Apr 2022

COVID-19 vaccine can elicit a distinct T cell-dominant immune-mediated hepatitis

In a recent study published in the Journal of Hepatology, researchers reported that the coronavirus disease 2019 (COVID-19) vaccination could elicit a distinct T cell-dominant immune-mediated hepatitis.

25 Apr 2022

Reprogrammed macrophages promote the settlement of breast cancer metastases in the lungs

Metastatic breast cancer cells abuse macrophages, a type of immune cell, to promote the settlement of cancer metastases in the lungs.

25 Apr 2022

Researchers develop new platform capable of mitochondrial DNA editing

Researchers from the Center for Genome Engineering within the Institute for Basic Science developed a new gene-editing platform called transcription activator-like effector-linked deaminases, or TALED.

25 Apr 2022

A potential way for overcoming immunotherapy resistance in patients with mucosal melanomas

The development of the anti-cancer immunotherapy drugs called immune checkpoint inhibitors has improved treatment for many cancer patients, but patients with mucosal melanomas - melanomas that occur not on the skin but in the mucous membranes in the head, neck, eyes, respiratory tract, and genitourinary region - are particularly resistant to immune checkpoint inhibitors for reasons researchers don't fully understand.

25 Apr 2022

New COVID-19 vaccine proven to be safe and effective in late-stage clinical testing

A COVID-19 vaccine developed at the University of Washington School of Medicine has proven safe and effective in late-stage clinical testing.

25 Apr 2022

MGH investigators find important regulators of urinary concentration in the kidney

Proper function of the kidney is critical for concentrating urine, regulating blood pressure, and for the tight control of electrolyte levels in the blood.

25 Apr 2022

Study reports increased numbers of SARS-CoV-2-reactive T cells in individuals who were HCoV-reactive

T cell responses were measured to three SARS-CoV-2-associated antigens, as well as the endemic coronaviruses HCoV-OC43 and HCoV-NL63.

25 Apr 2022

World Malaria Day 2022: How the knockdown of P. falciparum RAP01 and RAP21 proteins could lead to novel antimalarial therapeutics

As part of World Malaria Day 2022, we interview Karine Le Roch PH.D., about her latest research into how novel antimalarial therapeutic strategies could be on the horizon, after identifying two proteins that are critical to the survival of the malaria parasite, Plasmodium falciparum.

25 Apr 2022

Role of complement factor H-related protein 5 in venous thromboembolism and COVID-19

A new study discussed the role of complement factor H-related protein 5 (CFHR5) in venous thromboembolism (VTE) patients and hospitalized COVID-19 patients.

25 Apr 2022

The challenges of Omicron

A new review published in sums up the position of Omicron as a potential threat to human health, especially in the context of controlling this pandemic.

25 Apr 2022

Species differences in somatic mutations shed light on aging

A recent study published in the journal Nature aimed to elucidate, through a comparative analysis, the diversity in mutagenesis across different species, and the long-established hypothesis regarding evolution in the rates of somatic mutation, as well as their role in cancer and aging.

25 Apr 2022

Study suggests BCG vaccination might confer immunity to SARS-CoV-2

In a recent study posted to the bioRxiv* preprint server, the researchers investigated the impact of Bacillus Calmette-Guérin (BCG) vaccine-induced antibodies against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S) glycoprotein.

25 Apr 2022

Marine resources could be promising drug candidates against SARS-CoV-2 Omicron

A recent review paper, published in the MDPI’s specialized journal COVID, highlights key features of the Omicron variant of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – and examines the potential and roadblocks in using renewable marine resources in the fight against the coronavirus disease 2019 (COVID-19).

24 Apr 2022

Detection of prior SARS-CoV-2 infection by T-cell receptor sequencing

A new study describes a novel COVID-19 detection technique based on T-cell receptor sequencing.

24 Apr 2022

Quercetin and other plant flavonols show anti-SARS-CoV-2 activity

A new study discusses the potential of certain plant compounds to block SARS-CoV-2 replication within host cells.

24 Apr 2022

Study highlights a rapidly increasing patient population with long COVID and lack of treatments

A new UK study of more than 2,000 patients after hospitalization with COVID-19 presented at this year's European Congress of Clinical Microbiology & Infectious Diseases (ECCMID 2022, Lisbon 23-26), and published in The Lancet Respiratory Medicine shows that, one year after having COVID-19, only around one in four patients feel fully well again.

24 Apr 2022

Protein News and Research

Further Reading

A novel mouse model to test SARS-CoV-2 viral infection

Scientists discover how SARS-CoV-2 activates platelets

Increased power and amplitude of memory B cells after SARS-CoV-2 mRNA booster

Scientists show how T cells may help protect against severe COVID

COVID-19 vaccine can elicit a distinct T cell-dominant immune-mediated hepatitis

Reprogrammed macrophages promote the settlement of breast cancer metastases in the lungs

Researchers develop new platform capable of mitochondrial DNA editing

A potential way for overcoming immunotherapy resistance in patients with mucosal melanomas

New COVID-19 vaccine proven to be safe and effective in late-stage clinical testing

MGH investigators find important regulators of urinary concentration in the kidney

Study reports increased numbers of SARS-CoV-2-reactive T cells in individuals who were HCoV-reactive

World Malaria Day 2022: How the knockdown of P. falciparum RAP01 and RAP21 proteins could lead to novel antimalarial therapeutics

Role of complement factor H-related protein 5 in venous thromboembolism and COVID-19

The challenges of Omicron

Species differences in somatic mutations shed light on aging

Study suggests BCG vaccination might confer immunity to SARS-CoV-2

Marine resources could be promising drug candidates against SARS-CoV-2 Omicron

Detection of prior SARS-CoV-2 infection by T-cell receptor sequencing

Quercetin and other plant flavonols show anti-SARS-CoV-2 activity

Study highlights a rapidly increasing patient population with long COVID and lack of treatments

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