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Developing AI technology to detect early signs of Alzheimer's disease

With the support of a new grant worth $3.9 million, Michigan State University researchers are developing technology that scans speech and vocabulary patterns to catch early signs of Alzheimer's disease, the most common cause of dementia.

1 Jul 2021

Scientists discover genetic basis and molecular mechanisms of new neurodevelopmental syndrome

Scientists at the University of North Carolina at Chapel Hill School of Medicine and colleagues have demonstrated that variants in the SPTBN1 gene can alter neuronal architecture, dramatically affecting their function and leading to a rare, newly defined neurodevelopmental syndrome in children.

1 Jul 2021

Pandemic prompts scientists at Cincinnati Children's to focus on suicide prevention research efforts

The COVID-19 pandemic has prompted scientists at Cincinnati Children's Hospital Medical Center to pivot their suicide prevention research efforts with a focus on telehealth.

1 Jul 2021

Novel optical device could open new avenues in advanced microscopy

What if a microscope allowed us to explore the 3D microcosm of blood vessels, nerves, and cancer cells instantaneously in virtual reality? What if it could provide views from multiple directions in real time without physically moving the specimen and worked up to 100 times faster than current technology?

1 Jul 2021

Researchers develop the world's first digital cancer cell model

The computer model, developed under the lead management of researchers at TU Graz, simulates the cyclical changes in the membrane potential of a cancer cell using the example of human lung adenocarcinoma and opens up completely new avenues in cancer research.

1 Jul 2021

New mobile app could be useful in assessing symptom severity in chronic fatigue syndrome

Chronic fatigue syndrome / myalgic encephalomyelitis (CFS/ME) is a disabling disease, in which people have great difficulties in carrying out their daily activities.

1 Jul 2021

ERS Genomics and Nippon Gene sign CRISPR/Cas9 license agreement

ERS Genomics Limited, which was formed to provide broad access to the foundational CRISPR/Cas9 intellectual property co-owned by Dr. Emmanuelle Charpentier, and Nippon Gene Co., Ltd (Nippon Gene), a manufacturer of genetic engineering research reagents and diagnostic reagents for humans, animals, and plants, today announced a non-exclusive license agreement granting Nippon Gene access to ERS Genomics’ CRISPR/Cas9 patent portfolio.

1 Jul 2021

FDA revokes EUAs for non-NIOSH-approved respirators, decontamination systems

The following quote is attributed to Suzanne Schwartz, M.D., M.B.A., director of the Office of Strategic Partnerships and Technology Innovation in the FDA's Center for Devices and Radiological Health.

1 Jul 2021

New practice guideline includes recommendations for reducing blood loss during heart surgery

Four leading medical specialty societies released a new clinical practice guideline today that includes recommendations for reducing blood loss during heart surgery and improving patient outcomes.

1 Jul 2021

Cancer cells become more aggressive when exposed to tissue stiffening

In cases of breast cancer, bone metastasis - when cancer cells spread to new sites in the bone - causes the most breast cancer-related harm and is often incurable in advanced disease. A new study by University of Arizona Health Sciences researchers found that cancer cells become more aggressive when exposed to tissue stiffening and that these changes persist over time.

1 Jul 2021

New article focuses on drug discovery targeting SARS-CoV-2

The July edition of SLAS Discovery is a Special Edition featuring the cover article, "Development of a High-Throughput Screening Assay to Identify Inhibitors of the SARS-CoV-2 Guanine-N7-Methyltransferase Using RapidFire Mass Spectrometry" by Lesley-Anne Pearson, Charlotte J. Green, Ph.D., De Lin, Ph.D., Alain-Pierre Petit, Ph.D., David W. Gray, Ph.D., Victoria H. Cowling, Ph.D., and Euan A. F. Fordyce, Ph.D., (Drug Discovery Unit, School of Life Sciences, University of Dundee, Dundee, UK).

1 Jul 2021

New experimental model simulates the blood-brain barrier

Using an experimental model to simulate the blood-brain barrier, scientists in Sweden reported in unprecedented detail how antioxidants protect the brain from inflammation caused by neurodegenerative diseases such as Alzheimer's and Parkinson's.

1 Jul 2021

Scientists uncover new way to target a mutant protein that causes the deadliest of cancers

A new way to target a mutant protein which can cause the deadliest of cancers in humans has been uncovered by scientists at the University of Leeds.

30 Jun 2021

Breakthrough method for tracking mRNA molecules with fluorescence

Researchers at Chalmers University of Technology, Sweden, have succeeded in developing a method to label mRNA molecules, and thereby follow, in real time, their path through cells, using a microscope - without affecting their properties or subsequent activity.

30 Jun 2021

New research receives $2 million grant to determine if meningitis, sepsis increase Alzheimer's risk

The role of peripheral and brain infections in the development of Alzheimer's disease is the focus of new research at The University of Texas Health Science Center at Houston, funded with a $2 million grant from the National Institutes of Health.

30 Jun 2021

Researchers successfully implanted the first artificial tubular muscle in vivo

In January of this year, EPFL engineers announced in Advanced Science their concept of a novel cardiac assist device that is devoid of rigid metallic components. It consists of a soft, artificial muscle wrapped around the aorta that can constrict and dilate the vessel, ultimately enhancing the aorta's natural function and aiding the heart to pump blood to the rest of the body.

30 Jun 2021

New method to transport RNA-based drugs to subpopulation of immune cells

Tel Aviv University's groundbreaking technology may revolutionize the treatment of cancer and a wide range of diseases and medical conditions. In the framework of this study, the researchers were able to create a new method of transporting RNA-based drugs to a subpopulation of immune cells involved in the inflammation process, and target the disease-inflamed cell without causing damage to other cells.

30 Jun 2021

New neuronal circuit may help control which sensory information is relayed to the auditory cortex

A team of neuroscientists at the Beckman Institute for Advanced Science and Technology led by Baher Ibrahim and Dr. Daniel Llano published a study in eLife that furthers our understanding of how the brain perceives everyday sensory inputs.

30 Jun 2021

Innovative corona test offers great potential for systematic testing

A new corona test developed at the University Hospital Bonn can analyze a large number of swabs simultaneously using sequencing technology and has a similarly high sensitivity as the common qPCR test.

29 Jun 2021

BUSM receives $2.7 million grant to reduce disparities in cardio-oncology

With a growing need to better understand the many links between heart disease and cancer, the two leading causes of death worldwide, the American Heart Association, the world's leading voluntary organization dedicated to a world of longer, healthier lives, announced grants focused on this area of scientific research.

29 Jun 2021

Technology News and Research

Developing AI technology to detect early signs of Alzheimer's disease

Scientists discover genetic basis and molecular mechanisms of new neurodevelopmental syndrome

Pandemic prompts scientists at Cincinnati Children's to focus on suicide prevention research efforts

Novel optical device could open new avenues in advanced microscopy

Researchers develop the world's first digital cancer cell model

New mobile app could be useful in assessing symptom severity in chronic fatigue syndrome

ERS Genomics and Nippon Gene sign CRISPR/Cas9 license agreement

FDA revokes EUAs for non-NIOSH-approved respirators, decontamination systems

New practice guideline includes recommendations for reducing blood loss during heart surgery

Cancer cells become more aggressive when exposed to tissue stiffening

New article focuses on drug discovery targeting SARS-CoV-2

New experimental model simulates the blood-brain barrier

Scientists uncover new way to target a mutant protein that causes the deadliest of cancers

Breakthrough method for tracking mRNA molecules with fluorescence

New research receives $2 million grant to determine if meningitis, sepsis increase Alzheimer's risk

Researchers successfully implanted the first artificial tubular muscle in vivo

New method to transport RNA-based drugs to subpopulation of immune cells

New neuronal circuit may help control which sensory information is relayed to the auditory cortex

Innovative corona test offers great potential for systematic testing

BUSM receives $2.7 million grant to reduce disparities in cardio-oncology

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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