Efficacy News and Research

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Autologous hematopoietic cell transplant may induce sustained remission of multiple sclerosis

New clinical trial results provide evidence that high-dose immunosuppressive therapy followed by transplantation of a person's own blood-forming stem cells can induce sustained remission of relapsing-remitting multiple sclerosis (MS), an autoimmune disease in which the immune system attacks the central nervous system.

2 Feb 2017

New study explores patient and physician perspectives toward maternal placentophagy

Placentophagy--maternal consumption of the placenta--has become increasingly prevalent in the past decade among women seeking to promote health and healing during the postpartum period.

2 Feb 2017

Oral dose of phage cocktail prevents infection and cholera-like symptoms in animal model

Oral administration of a cocktail of three viruses, all of which specifically kill cholera bacteria, prevents infection and cholera-like symptoms in animal model experiments, report scientists from Tufts University School of Medicine and the Sackler School of Graduate Biomedical Sciences at Tufts in Nature Communications on Feb. 1.

1 Feb 2017

New review examines use of probiotics or prebiotics for prevention of atopic dermatitis

Evidence supporting a key role for an altered gut microbiome in the development of atopic dermatitis would suggest that the use of probiotics or prebiotics to correct microbial imbalances in the gut could help prevent or treat AD.

31 Jan 2017

Mini-gut model provides clues to enterovirus infections in infants

Using immature stem cells to create a miniature model of the gut in the laboratory, researchers at Washington University School of Medicine in St. Louis and the University of Pittsburgh have determined how infection-causing enteroviruses enter the intestine.

31 Jan 2017

Scientists develop unique method to fix genes in living organisms

A unique gene-editing method that efficiently inserts DNA into genes located in dividing and non-dividing cells of living rats has been developed by a team of international researchers, including scientists from KAUST.

31 Jan 2017

Measuring BTMs could be practical way to identify patient's adherence to osteoporosis medications

Oral bisphosphonates are common first line treatments for osteoporosis. However, approximately half of patients who begin osteoporosis treatment do not follow their prescribed treatment and/or discontinue treatment within a year.

30 Jan 2017

First-time drug trials launched on basis of flimsy, under-scrutinized evidence, say McGill researchers

Standards for authorizing first-time trials of drugs in humans are lax, and should be strengthened in several ways, McGill University researchers argue in a paper published today in Nature.

30 Jan 2017

Interventions that change the brain may promote resilience and improved mental health

In an article published in the current issue of Psychotherapy and Psychosomatic Dr. Bruce McEwen (Rockefeller University) analyzes promising outlooks that interventions that affect brain may have on health.

28 Jan 2017

Pulmospheres could serve as personalized, predictive model for assessing effect of IPF drugs

Pulmospheres, three dimensional multicellular spheroids composed of lung cells from individual patients, were shown to be effective in predicting the efficacy of medications for idiopathic pulmonary fibrosis, according to findings from University of Alabama at Birmingham scientists presented today in JCI Insight, a journal of the American Society for Clinical Investigation.

27 Jan 2017

Joslin scientists suggest new approach to improve stroke therapy

The standard of care for treating strokes caused by blood clots involves the therapeutic infusion of tissue plasminogen activator (tPA), which can help to dissolve the clots and restore blood flow.

27 Jan 2017

Tonsillectomies provide modest short-term benefits for children, Vanderbilt review reveals

Removing tonsils modestly reduced throat infections in the short term in children with moderate obstructive sleep-disordered breathing or recurrent throat infections, according to a systematic review conducted by the Vanderbilt Evidence-based Practice Center for the Agency for Healthcare Research and Quality.

25 Jan 2017

Scientists discover cause of tumour resistance to angiogenesis inhibitors

A new study conducted by MedUni Vienna in collaboration with scientists from Hungary and Sweden has now shown for the first time that the success of specialised drugs to inhibit blood supply to tumours - so-called angiogenesis inhibitors - is compromised by the fact that these drugs do not effectively penetrate the tumour tissue and so do not reach the smallest blood vessels in the tumour.

25 Jan 2017

Timing of chemotherapy can have big effect on inflammation, study shows

The time of day that breast cancer chemotherapy drugs are given affects the amount of damaging inflammation in the body, a new study in mice suggests.

24 Jan 2017

New therapy to treat spinal cord injuries shows improvements in motor function

A new therapy to treat spinal cord injuries in people who have lost all motor and sensory function below the injury site shows additional motor function improvement at 6-months and 9-months following treatment with 10 million AST-OPC1.

24 Jan 2017

Researchers find new way to quantify olfactory sensory neurons using PET radiotracer

Olfactory health - how well we are able to smell - is a reliable marker of the health of the brain, but the "smell identification tests" commonly used in studies of olfactory health do not offer a complete picture of what is happening.

24 Jan 2017

Researchers evaluate use of regenerative human umbilical cord for in-utero spina bifida repair

In a study to be presented Saturday, Jan. 28, in the oral concurrent session at 8:45 a.m. PST, at the Society for Maternal-Fetal Medicine's annual meeting, The Pregnancy Meeting, researchers evaluated a possible regenerative patch by using human umbilical cord in two studies titled Cryopreserved Human Umbilical Cord (HUC) vs Acellular Dermal Matrix (ADM) for In-Utero Spina Bifida Repair and the study Conventional vs cryopreserved human umbilical cord (HUC) patch based on repair for in-utero spina bifida in a sheep model.

23 Jan 2017

New biomarker helps better predict survival after surgical removal of colorectal metastases

Liver metastases are formed from cancer cells that have originated in other organs and migrated to the liver via the bloodstream. Colorectal cancer (cancer of the colon/rectum) can be successfully treated by surgical resection of the metastases in combination with chemotherapy.

23 Jan 2017

FDA approves new oral medication for treating chronic idiopathic constipation in adult patients

The U.S. Food and Drug Administration today approved Trulance (plecanatide) for the treatment of Chronic Idiopathic Constipation (CIC) in adult patients.

19 Jan 2017

Biosimilars create chances to improve sustainability and affordability of cancer treatment

Biosimilars create opportunities for sustainable cancer care, says the European Society for Medical Oncology (ESMO) in a position paper published in ESMO Open.

18 Jan 2017

Efficacy News and Research

Autologous hematopoietic cell transplant may induce sustained remission of multiple sclerosis

New study explores patient and physician perspectives toward maternal placentophagy

Oral dose of phage cocktail prevents infection and cholera-like symptoms in animal model

New review examines use of probiotics or prebiotics for prevention of atopic dermatitis

Mini-gut model provides clues to enterovirus infections in infants

Scientists develop unique method to fix genes in living organisms

Measuring BTMs could be practical way to identify patient's adherence to osteoporosis medications

First-time drug trials launched on basis of flimsy, under-scrutinized evidence, say McGill researchers

Interventions that change the brain may promote resilience and improved mental health

Pulmospheres could serve as personalized, predictive model for assessing effect of IPF drugs

Joslin scientists suggest new approach to improve stroke therapy

Tonsillectomies provide modest short-term benefits for children, Vanderbilt review reveals

Scientists discover cause of tumour resistance to angiogenesis inhibitors

Timing of chemotherapy can have big effect on inflammation, study shows

New therapy to treat spinal cord injuries shows improvements in motor function

Researchers find new way to quantify olfactory sensory neurons using PET radiotracer

Researchers evaluate use of regenerative human umbilical cord for in-utero spina bifida repair

New biomarker helps better predict survival after surgical removal of colorectal metastases

FDA approves new oral medication for treating chronic idiopathic constipation in adult patients

Biosimilars create chances to improve sustainability and affordability of cancer treatment

Industry Focus eBook - Analytical Chemistry (2nd Edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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