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Researchers outline novel molecular interactions affecting key cancer pathway in humans

Researchers from the Cancer Science Institute of Singapore at the National University of Singapore have delineated novel molecular interactions affecting the activity of the TGF-β pathway, a key cancer pathway in humans affecting cancer progression.

22 Dec 2015

Patients with EGFR-mutated lung cancer benefit more from afatinib as first-line treatment

Patients with EGFR-activating mutations in advanced lung cancer seem to benefit more from afatinib than gefitinib as first-line treatment, researchers report at the first ESMO Asia 2015 Congress in Singapore.

21 Dec 2015

Many patients continue working after metastatic cancer diagnosis, study finds

A new analysis indicates that many patients continue working after being diagnosed with metastatic cancer, but a heavy burden of symptoms may prevent them from doing so. Published early online in CANCER, a peer-reviewed journal of the American Cancer Society, the study illustrates the need to treat difficult symptoms so that patients can maintain their employment.

21 Dec 2015

Nuvo Research announces topline results from WF10 Phase 2 trial for treatment of allergic rhinitis

Nuvo Research Inc., a life sciences company with growing revenues and a diverse portfolio of topical products, today announced the results of its investigational Phase 2 clinical trial of WF10 (Trial) for the treatment of allergic rhinitis.

21 Dec 2015

Aquinnah secures $5 million private equity investment from Takeda

Aquinnah Pharmaceuticals announced today that it has received a $5 Million investment from Takeda Pharmaceutical Company, Limited, in it's first private equity financing. The company has assembled a world-class team of drug developers and an exceptional Scientific Advisory Board in the fields of Amyotrophic Lateral Sclerosis (ALS), protein and RNA regulation, and neurodegenerative diseases.

21 Dec 2015

Halozyme Therapeutics, Lilly sign global collaboration and license agreement

Halozyme Therapeutics, Inc. today announced a global collaboration and license agreement with Eli Lilly and Company to develop and commercialize products combining proprietary Lilly compounds with Halozyme's ENHANZE platform.

21 Dec 2015

New study improves understanding of metal-based chemotherapy drugs

What is the mechanism of action of metal-based chemotherapy drugs (the most widely used for treating common cancers like testicular or ovarian cancer)? How can we improve their effect and reduce their toxicity? A new study combining experiments and theory has broadened our knowledge of the molecular mechanisms of these active drugs to help experimentalists devising increasingly effective drugs with fewer side effects.

21 Dec 2015

Targeted alpha therapy has potential to reduce HIV-infected cells from central nervous system

Targeted alpha therapy has the potential to selectively eliminate HIV infected cells from the central nervous system, according to a recent study co-authored by the JRC. The study shows that a specific human antibody labelled with the alpha emitter bismuth-213 can penetrate the blood brain barrier and selectively target and destroy HIV-infected cells while sparing non-infected healthy cells.

21 Dec 2015

Heidelberg neurobiologists identify Dnmt3a2 protein that boosts memory performance

Increasing the level of a certain DNA-modified enzyme in the brain significantly improves cognitive ability. The discovery was made by the research team led by Prof. Dr. Hilmar Bading at the Interdisciplinary Center for Neurosciences of Heidelberg University. Mouse experiments showed that the Dnmt3a2 protein can boost memory performance in the animals.

21 Dec 2015

New Griffith University study focuses on improving perinatal mental health in women

Addressing the barriers that can prevent midwives helping mothers overcome a fear of childbirth is the focus of a new study at Griffith University.

21 Dec 2015

Periodontal disease may increase breast cancer risk

Postmenopausal women with periodontal disease were more likely to develop breast cancer than women who did not have the chronic inflammatory disease. A history of smoking significantly affected the women's risk.

21 Dec 2015

Univercells awarded grant to reduce cost of vaccine manufacturing in the Walloon region

Univercells SA, a company that designs single-use cost-efficient bioprocess solutions for the next generation of biomanufacturing, today announces that it has received a grant from the Walloon region.

21 Dec 2015

Regulus begins RG-125(AZD4076) Phase I study for treatment of NASH in patients with type 2 diabetes/pre-diabetes

Regulus Therapeutics Inc., a biopharmaceutical company leading the discovery and development of innovative medicines targeting microRNAs, announced today that dosing has begun in a first-in-human Phase I clinical study of RG-125(AZD4076), by its collaboration partner AstraZeneca.

21 Dec 2015

Certain gut bacteria linked to type 2 diabetes, reveal Russian scientists

A group of Russian scientists, including Dr Elena Kostryukova, the Head of the Laboratory of Postgenomic Research in Biology of the Scientific Research Institute of Physical-Chemical Medicine and a researcher at MIPT (Moscow Institute of Physics and Technology), and Maria Vakhitova, an MIPT postgraduate student, has discovered that the presence of certain bacteria in the gut may be linked to the development of type 2 diabetes.

21 Dec 2015

Harley Street Fertility Clinic encourages couples to have more sex to increase chances of conception

Today, one of the UK’s leading fertility experts warns that couples with busy lives are not engaging in enough sexual intercourse and this is therefore impacting the nations fertility.

21 Dec 2015

Researchers invited to showcase latest advances in surgical robot technologies at Surgical Robot Challenge

The world’s pioneering researchers in robotic surgery are invited to showcase their innovative work by taking part in the Surgical Robot Challenge 2016. The Surgical Robot Challenge is open for entry from today, and the competition finals will be held from 20 – 27 June 2016 at the Hamlyn Symposium on Medical Robotics in London, as part of the first ever UK Robotics Week.

21 Dec 2015

Flu vaccine: the facts. An interview with Dr Lisa Maragakis

There are different formulations of the flu vaccine but in general they all do the same thing, which is to stimulate our body's immune system to recognize and fight against the influenza virus.

21 Dec 2015

TeleHealth Services, UbiCare partner to provide unique patient education and engagement solution

TeleHealth Services and UbiCare announce an exclusive business partnership that provides a unique, proven patient education and engagement solution for hospitals, healthcare systems, clinics and ambulatory centers.

21 Dec 2015

TSRI-led study finds potential new therapeutic approach for hard-to-treat breast cancers

Findings from a new study led by scientists from the Florida campus of The Scripps Research Institute (TSRI) suggest a potent new therapeutic approach for a number of hard-to-treat breast cancers.

21 Dec 2015

MorphoSys implements Dotmatics’ Vortex to improve antibody research

Dotmatics, a leading provider of scientific informatics solutions and services, announced MorphoSys will implement Vortex to analyse and visualise their screening data enabling rapid, informed decision making. MorphoSys choose Vortex because of the intuitive nature of the product and its extensive drug discovery capabilities.

21 Dec 2015

Research News and Research

Researchers outline novel molecular interactions affecting key cancer pathway in humans

Patients with EGFR-mutated lung cancer benefit more from afatinib as first-line treatment

Many patients continue working after metastatic cancer diagnosis, study finds

Nuvo Research announces topline results from WF10 Phase 2 trial for treatment of allergic rhinitis

Aquinnah secures $5 million private equity investment from Takeda

Halozyme Therapeutics, Lilly sign global collaboration and license agreement

New study improves understanding of metal-based chemotherapy drugs

Targeted alpha therapy has potential to reduce HIV-infected cells from central nervous system

Heidelberg neurobiologists identify Dnmt3a2 protein that boosts memory performance

New Griffith University study focuses on improving perinatal mental health in women

Periodontal disease may increase breast cancer risk

Univercells awarded grant to reduce cost of vaccine manufacturing in the Walloon region

Regulus begins RG-125(AZD4076) Phase I study for treatment of NASH in patients with type 2 diabetes/pre-diabetes

Certain gut bacteria linked to type 2 diabetes, reveal Russian scientists

Harley Street Fertility Clinic encourages couples to have more sex to increase chances of conception

Researchers invited to showcase latest advances in surgical robot technologies at Surgical Robot Challenge

Flu vaccine: the facts. An interview with Dr Lisa Maragakis

TeleHealth Services, UbiCare partner to provide unique patient education and engagement solution

TSRI-led study finds potential new therapeutic approach for hard-to-treat breast cancers

MorphoSys implements Dotmatics’ Vortex to improve antibody research

eBook: Advancing neurodegenerative research with iPSC-derived microglia models eBook

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