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New therapeutic strategy can prevent dental decay in children

The combination of a carb-heavy diet and poor oral hygiene can leave children with early childhood caries (ECC), a severe form of dental decay that can have a lasting impact on their oral and overall health.

19 May 2021

Connecticut's MAT programs have higher-than-average patient retention rates

Medication-assisted treatment, or MAT, is an important tool in the ongoing fight against opioid use dependence in the United States.

19 May 2021

Scientists develop experimental direct-acting antiviral therapy to treat COVID-19

An international team of scientists from the Menzies Health Institute Queensland (MHIQ) at Griffith University and from City of Hope, a research and treatment center for cancer, diabetes and other life-threatening diseases in the U.S., have developed an experimental direct-acting antiviral therapy to treat COVID-19.

18 May 2021

Researchers report promising biotherapeutics for obesity and related medical complications

The research teams at the University of Hong Kong led by Professor Xuechen LI from the Research Division for Chemistry and Department of Chemistry, and Professor Yu WANG from the Department of Pharmacology and Pharmacy, reported a synthetic biotherapeutics with promising anti-tumor, insulin sensitising and hepatoprotective activities in the Journal of the American Chemical Society.

18 May 2021

Researchers investigate immune molecule that helps protect transplanted kidneys

Looking to improve organ transplant success, researchers are working to learn more about how an immune molecule, which also protects a fetus, helps protect some transplanted kidneys, and to develop a synthetic version of that molecule that could help more patients.

18 May 2021

Omecamtiv mecarbil significantly reduces hospitalizations among patients with severe heart failure

The experimental heart failure drug omecamtiv mecarbil reduced heart failure hospitalizations by a greater margin among patients with more severely reduced ejection fraction, a measure indicating severe impairment in the heart's pumping ability, compared with those who had moderately reduced ejection fraction, according to research presented at the American College of Cardiology's 70th Annual Scientific Session.

18 May 2021

New technology tricks tumors to eliminate itself through the production of anti-cancer agents

Scientists at the University of Zurich have modified a common respiratory virus, called adenovirus, to act like a Trojan horse to deliver genes for cancer therapeutics directly into tumor cells. Unlike chemotherapy or radiotherapy, this approach does no harm to normal healthy cells.

18 May 2021

New cardiac rehabilitation intervention improves quality of life in hospitalized heart failure patients

An innovative cardiac rehabilitation intervention started earlier and more custom-tailored to the individual improved physical function, frailty, quality-of-life, and depression in hospitalized heart failure patients, compared to traditional rehabilitation programs.

17 May 2021

‘Kicking you when you’re down’: Many cancer patients pay dearly for parking

For cancer patients, the road from diagnosis to survivorship feels like a never-ending parade of medical appointments: surgeries, bloodwork, chemotherapy, radiation treatments, scans.

17 May 2021

Sphere Fluidics announces enhanced Cyto-Mine capability and performance

Sphere Fluidics, a company developing single-cell analysis systems, today announced it has enhanced the performance of its Cyto-Mine® System.

From Fluidic Sciences and Sphere Bio 17 May 2021

Rivaroxaban reduces the occurrence of severe ischemic events in patients with peripheral artery disease

Rivaroxaban, in addition to low-dose aspirin, significantly reduced the occurrence of total severe events of the heart, limb or brain and issues related to other vascular complications in patients with symptomatic peripheral artery disease (PAD) who underwent lower extremity revascularization, a procedure to open blocked arteries in the leg.

17 May 2021

UNSW researchers find novel way to attack the 'fortress' surrounding pancreatic tumors

Tackling the scar tissue that shields pancreatic tumors from effective drug access is a promising advance in a notoriously hard-to-treat cancer.

17 May 2021

Nanotechnology and COVID-19 diagnosis and treatment

The development of nano-biosensors and nanoparticle-based vaccines and medicines has opened a new path toward better management of the coronavirus disease 2019 (COVID-19) pandemic. In a recently published article in the journal ACS Biomaterials Science & Engineering, scientists have reviewed recent advancements in nanotechnology-based diagnostic and therapeutic interventions against human coronaviruses.

17 May 2021

Investigational drug reduced triglycerides in patients with severe hypertriglyceridemia, acute pancreatitis

The investigational drug evinacumab reduced triglycerides in patients with severe hypertriglyceridemia (sHTG) and a history of hospitalizations for acute pancreatitis in a phase 2 global study led by Mount Sinai.

17 May 2021

Brief pulses of ultrasound delivered to nerves in renal arteries reduce drug-resistant blood pressure

Brief pulses of ultrasound delivered to nerves near the kidney produced a clinically meaningful drop in blood pressure in people whose hypertension did not respond to a triple cocktail of medications, reports a new study led by researchers at Columbia University Vagelos College of Physicians and Surgeons and NewYork-Presbyterian.

17 May 2021

Older heart failure patients significantly benefit from tailored cardiac rehab program

Older patients hospitalized with acute heart failure who participated in a novel 12-week physical rehabilitation (rehab) program tailored to address their specific physical impairments had significant gains not only in physical functioning but also quality of life and depression compared with those receiving usual care, regardless of their heart's ejection fraction, according to a new study presented at the American College of Cardiology's 70th Annual Scientific Session.

17 May 2021

Sacubitril/valsartan drug did not significantly reduce cardiovascular death after heart attack

The heart failure drug sacubitril/valsartan did not significantly reduce the rate of heart failure or cardiovascular death following a heart attack compared to ramipril, an angiotensin-converting enzyme (ACE) inhibitor proven effective in improving survival following heart attacks.

17 May 2021

Unique pre-clinical model enables study of HIV infection and testing of new therapies

A team led by researchers at Weill Cornell Medicine and Children's National Hospital has developed a unique pre-clinical model that enables the study of long-term HIV infection, and the testing of new therapies aimed at curing the disease.

14 May 2021

Farxiga approved in the US for the treatment of chronic kidney disease in patients at risk of progression with and without type-2 diabetes

Approval is the most significant advancement in the treatment of chronic kidney disease in more than 20 years. In DAPA-CKD Phase III trial, Farxiga demonstrated unprecedented reduction in the risk of the composite of worsening of renal function, end-stage kidney disease and cardiovascular or renal death.

From AstraZeneca 14 May 2021

Researchers evaluate diagnostic criteria for anti-NMDA receptor encephalitis in Japanese children

Anti-NMDA receptor (NMDAR) encephalitis was first reported to develop in female young adults with ovarian teratoma.

13 May 2021

Therapy News and Research

New therapeutic strategy can prevent dental decay in children

Connecticut's MAT programs have higher-than-average patient retention rates

Scientists develop experimental direct-acting antiviral therapy to treat COVID-19

Researchers report promising biotherapeutics for obesity and related medical complications

Researchers investigate immune molecule that helps protect transplanted kidneys

Omecamtiv mecarbil significantly reduces hospitalizations among patients with severe heart failure

New technology tricks tumors to eliminate itself through the production of anti-cancer agents

New cardiac rehabilitation intervention improves quality of life in hospitalized heart failure patients

‘Kicking you when you’re down’: Many cancer patients pay dearly for parking

Sphere Fluidics announces enhanced Cyto-Mine capability and performance

Rivaroxaban reduces the occurrence of severe ischemic events in patients with peripheral artery disease

UNSW researchers find novel way to attack the 'fortress' surrounding pancreatic tumors

Nanotechnology and COVID-19 diagnosis and treatment

Investigational drug reduced triglycerides in patients with severe hypertriglyceridemia, acute pancreatitis

Brief pulses of ultrasound delivered to nerves in renal arteries reduce drug-resistant blood pressure

Older heart failure patients significantly benefit from tailored cardiac rehab program

Sacubitril/valsartan drug did not significantly reduce cardiovascular death after heart attack

Unique pre-clinical model enables study of HIV infection and testing of new therapies

Farxiga approved in the US for the treatment of chronic kidney disease in patients at risk of progression with and without type-2 diabetes

Researchers evaluate diagnostic criteria for anti-NMDA receptor encephalitis in Japanese children

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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