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Occupational therapy holds potential to provide clinical benefits to dementia patients

A French observational study in real life showed that dementia patients benefiting from occupational therapy sessions report relevant clinical benefits over the intervention period, according to a research study published in the Journal of Alzheimer's Disease this month.

22 Dec 2016

Generative AAE can be radically new way to discover drugs on demand

Scientists at the Pharmaceutical Artificial Intelligence group of Insilico Medicine, Inc, today announced the publication of a seminal paper demonstrating the application of generative adversarial autoencoders (AAEs) to generating new molecular fingerprints on demand.

22 Dec 2016

OPERA study evaluates patient perceptions of pain treatment with use of transdermal formulations

Clarity, a global international scientific research company, based in Austin, Texas, announces the latest results of its IRB-approved OPERA study.

21 Dec 2016

UT Southwestern researchers find new way to combat multidrug-resistant bacteria in burn injuries

A new way to fight multidrug-resistant bacteria by blinding them rather than killing them proved highly effective in a model of burn injuries, UT Southwestern Medical Center research shows.

21 Dec 2016

Clinical study tests adult stem cell therapy for infants with congenital HLHS

In a first-in-children randomized clinical study, medical researchers at the University of Maryland School of Medicine and the Interdisciplinary Stem Cell Institute at the University of Miami Miller School of Medicine have begun testing to see whether adult stem cells derived from bone marrow benefit children with the congenital heart defect hypoplastic left heart syndrome (HLHS).

21 Dec 2016

First large-scale clinical study of long-acting injectable HIV drug begins

The first large-scale clinical trial of a long-acting injectable drug for HIV prevention began today.

21 Dec 2016

Study compares medications for treatment of persons with recurrent genital herpes

In a study appearing in the December 20 issue of JAMA, Anna Wald, M.D., M.P.H., of the University of Washington & Fred Hutchinson Cancer Research Center, Seattle, and colleagues compared the medications pritelivir and valacyclovir for reducing genital herpes simplex virus shedding and lesions in persons with recurrent genital herpes.

20 Dec 2016

$New review explores approaches for prevention of hip fracture in very high risk patients$

New review explores approaches for prevention of hip fracture in very high risk patients

Hip fractures are of great concern as they are the most severe type of fracture in osteoporotic patients, associated with premature death, and commonly leading to long-term physical disability, impaired capacity to perform daily activities and live independently, and reduced quality of life.

20 Dec 2016

FDA awards accelerated approval to new ovarian cancer drug

The U.S. Food and Drug Administration today granted accelerated approval to Rubraca (rucaparib) to treat women with a certain type of ovarian cancer.

19 Dec 2016

Novel approach can regenerate dental pulp-like tissues in animal model

When a tooth is damaged, either by severe decay or trauma, the living tissues that comprise the sensitive inner dental pulp become exposed and vulnerable to harmful bacteria.

19 Dec 2016

New guidelines highlight safety, efficacy of surgical ablation for treating atrial fibrillation

New clinical practice guidelines have been issued by The Society of Thoracic Surgeons that include major recommendations for the use of surgical ablation when treating atrial fibrillation (Afib), the most common type of irregular heartbeat.

19 Dec 2016

Study addresses cost-effectiveness of checkpoint inhibitors for advanced melanoma in Hong Kong

Immunotherapy with pembrolizumab has been deemed a cost-effective first line treatment for advanced melanoma patients in Hong Kong, researchers report at the ESMO Asia 2016 Congress in Singapore.

17 Dec 2016

Combined endocrine and targeted therapy could be effective in treating Asian breast cancer patients

Ribociclib significantly improves progression-free survival in Asian women with advanced breast cancer, according to a sub-analysis of the MONALEESA-2 trial presented at the ESMO Asia 2016 Congress in Singapore.

17 Dec 2016

New clinical study for children with AML aims to kill leukemia cells and minimize cardiac damage

Imagine conquering childhood cancer, only to find out that years down the road your heart may fail.

17 Dec 2016

Common heartburn medications could decrease effects of chemotherapy in cancer patients

Something as seemingly harmless as a heartburn pill could lead cancer patients to take a turn for the worse.

16 Dec 2016

Novel computer tool predicts impact of short-course treatment regimen against MDR-TB

Johns Hopkins researchers have developed a computer simulation that helps predict under which circumstances a new short-course treatment regimen for drug-resistant tuberculosis could substantially reduce the global incidence and spread of the disease.

16 Dec 2016

Researchers develop promising therapeutic antibodies against tumor-promoting MMPs

Researchers at the University of California, Riverside have camels and llamas to thank for their development of a new cancer treatment that is highly selective in blocking the action of faulty matrix metalloproteinases (MMPs).

16 Dec 2016

Researchers identify attractive drug candidate to target glioma tumors

In a paper published today in Cancer Research, researchers: 1) identify a biomarker enzyme associated with aggressive glioma brain tumors, 2) reveal the regulatory mechanism for that enzyme, and 3) demonstrate potent efficacy, using a mouse model of glioma, for a small molecule inhibitor they have developed.

16 Dec 2016

FDA approves new treatment option for patients dealing with mild to moderate eczema

The U.S. Food and Drug Administration today approved Eucrisa (crisaborole) ointment to treat mild to moderate eczema (atopic dermatitis) in patients two years of age and older.

14 Dec 2016

Phenotypic Personalized Medicine could surmount treatment challenges for acute lymphoblastic leukemia

A team of UCLA bioengineers has demonstrated that its technology may go a long way toward overcoming the challenges of treatment for acute lymphoblastic leukemia, among the most common types of cancer in children, and has the potential to help doctors personalize drug doses.

14 Dec 2016

Efficacy News and Research

Occupational therapy holds potential to provide clinical benefits to dementia patients

Generative AAE can be radically new way to discover drugs on demand

OPERA study evaluates patient perceptions of pain treatment with use of transdermal formulations

UT Southwestern researchers find new way to combat multidrug-resistant bacteria in burn injuries

Clinical study tests adult stem cell therapy for infants with congenital HLHS

First large-scale clinical study of long-acting injectable HIV drug begins

Study compares medications for treatment of persons with recurrent genital herpes

New review explores approaches for prevention of hip fracture in very high risk patients

FDA awards accelerated approval to new ovarian cancer drug

Novel approach can regenerate dental pulp-like tissues in animal model

New guidelines highlight safety, efficacy of surgical ablation for treating atrial fibrillation

Study addresses cost-effectiveness of checkpoint inhibitors for advanced melanoma in Hong Kong

Combined endocrine and targeted therapy could be effective in treating Asian breast cancer patients

New clinical study for children with AML aims to kill leukemia cells and minimize cardiac damage

Common heartburn medications could decrease effects of chemotherapy in cancer patients

Novel computer tool predicts impact of short-course treatment regimen against MDR-TB

Researchers develop promising therapeutic antibodies against tumor-promoting MMPs

Researchers identify attractive drug candidate to target glioma tumors

FDA approves new treatment option for patients dealing with mild to moderate eczema

Phenotypic Personalized Medicine could surmount treatment challenges for acute lymphoblastic leukemia

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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