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Experimental gene therapy successfully treats children born without an immune system

An experimental form of gene therapy developed by a team of researchers from UCLA and Great Ormond Street Hospital in London has successfully treated 48 of 50 children born with a rare and deadly inherited disorder that leaves them without an immune system.

11 May 2021

New tool may safely block gene linked to factors that cause heart disease

Looking to safely block a gene linked to factors known to cause heart disease, scientists at the University of Colorado Anschutz Medical Campus may have found a new tool - light.

11 May 2021

Experts discuss the synergistic effects of acoustics-based therapy and cancer immunotherapy

Announcing a new article publication for BIO Integration journal. In this review the authors Yuheng Bao, Jifan Chen, Pintong Huang and Weijun Tong from Zhejiang University, Hangzhou, China discuss the synergistic effects of acoustics-based therapy and immunotherapy in cancer treatment.

11 May 2021

Severe COVID-19 linked to genetic clotting predisposition

Thus, the need to stratify the risk of severe or critical disease in patients presenting with SARS-CoV-2 infection remains a crying necessity. A new preprint research paper posted to the medRxiv server discusses the relationship between severe disease and pre-existing susceptibility to clots and other diseases of the cardiovascular system.

11 May 2021

Reversible pharmacological treatment can improvise stuttering in humans

Speech problems such as stammering or stuttering plague millions of people worldwide, including 3 million Americans.

11 May 2021

Natural products a rich source for novel antiviral compounds

In a recent review in the journal Viruses, researchers look at natural products that can be identified as potential alternative antiviral agents. The reviewers discussed the antiviral activities of several natural products towards DNA and RNA viruses with an analytical approach. The researchers detailed the cellular/viral targets of the active molecules and their impact on the infection and viral replication cycle.

10 May 2021

Key protein helps bacteria that causes Legionnaires' disease to set up house in host cells

Scientists at UT Southwestern have discovered a key protein that helps the bacteria that causes Legionnaires' disease to set up house in the cells of humans and other hosts.

10 May 2021

CDK inhibitors may boost the effectiveness of immune therapy in metastatic breast cancer

A class of drugs that inhibits breast cancer progression when used with hormonal therapy might also boost the effectiveness of immune therapy in cases of recurrent, metastatic breast cancer, according to a new study led by researchers at The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute.

10 May 2021

Cognitive problems caused by repetitive and mild blows to the head could be treated, study suggests

A neurologic pathway by which non-damaging but high frequency brain impact blunts normal brain function and causes long-term problems with learning and memory has been identified.

10 May 2021

Grand Challenge research integrates AI to streamline clinical assessment of breast cancer

Breast cancer has recently overtaken lung cancer to become the most common cancer globally, according to the World Health Organization.

10 May 2021

New filling method to treat cerebral aneurysms

Cerebral aneurysms are malformations caused by abnormalities on the walls of blood vessels in the brain. When these blood vessels rupture, about 30% of the sufferers die on the spot, giving these the rightful label of 'ticking bombs in the head'.

10 May 2021

New technique can help to non-invasively assess progression of sickle cell retinopathy

Ophthalmologists at New York Eye and Ear Infirmary of Mount Sinai have created a new technique to evaluate patients with sickle cell retinopathy and assess the disease before it progresses and leads to permanent vision loss.

10 May 2021

Novel approach to immunotherapy design could pave the way for new brain cancer treatments

A novel approach to immunotherapy design could pave the way for new treatments for people with an aggressive form of brain cancer called glioblastoma.

10 May 2021

Researchers identify first biomarker to predict severity of COVID-19

Severe cases of COVID-19 can now be detected at an early stage. Researchers at the University of Zurich have identified the first biomarker that can reliably predict which patients will develop severe symptoms.

10 May 2021

New nanoimmunoassay can detect anti–SARS-CoV-2 antibodies in ultralow-volume blood samples

In a recent study, researchers developed and validated a nanoimmunoassay (NIA) that analyzes 1,024 samples in parallel on a single microfluidic device the size of a USB stick. They detected anti-SARS-CoV-2 IgG antibodies, achieving a sensitivity of 98% and specificity of 100% based on an analysis of 134 pre-pandemic sera (collected in 2013/2014 and 2018) and 155 sera from reverse transcription-polymerase chain reaction (RT-PCR) positive individuals.

10 May 2021

Researchers examine how neighborhood and social network affect binge drinking among adults

For some people, social gatherings can be a time to imbibe. And for some, that can turn into a time to overindulge. But how do your neighborhood and your social network affect binge drinking?

7 May 2021

Absence of key gene causes severe hearing loss

A gene called GAS2 plays a key role in normal hearing, and its absence causes severe hearing loss, according to a study led by researchers in the Perelman School of Medicine at the University of Pennsylvania.

7 May 2021

Using ultrasound and RNA-loaded nanoparticles to deliver potent medicine to brain tumors

RNA-based drugs have the potential to change the standard of care for many diseases, making personalized medicine a reality. This rapidly expanding class of therapeutics are cost-effective, fairly easy to manufacture, and able to go where no drug has gone before, reaching previously undruggable pathways.

7 May 2021

CFTR modulator can be safe, well-tolerated for younger children with common form of cystic fibrosis

Children ages two to five who have the most common form of cystic fibrosis (CF), caused by two copies of the F508 gene mutation, have not had any modulator treatments available to them until recently.

7 May 2021

Supervised rehabilitation program can help patients with lasting symptoms of COVID-19

Patients with lasting symptoms of COVID-19 who completed a six week, supervised rehabilitation programme demonstrated significant improvements in exercise capacity, respiratory symptoms, fatigue and cognition, according to researchers at the National Institute for Health Research Leicester Biomedical Research Centre - a partnership between Leicester's Hospitals, the University of Leicester and Loughborough University.

7 May 2021

Therapy News and Research

Experimental gene therapy successfully treats children born without an immune system

New tool may safely block gene linked to factors that cause heart disease

Experts discuss the synergistic effects of acoustics-based therapy and cancer immunotherapy

Severe COVID-19 linked to genetic clotting predisposition

Reversible pharmacological treatment can improvise stuttering in humans

Natural products a rich source for novel antiviral compounds

Key protein helps bacteria that causes Legionnaires' disease to set up house in host cells

CDK inhibitors may boost the effectiveness of immune therapy in metastatic breast cancer

Cognitive problems caused by repetitive and mild blows to the head could be treated, study suggests

Grand Challenge research integrates AI to streamline clinical assessment of breast cancer

New filling method to treat cerebral aneurysms

New technique can help to non-invasively assess progression of sickle cell retinopathy

Novel approach to immunotherapy design could pave the way for new brain cancer treatments

Researchers identify first biomarker to predict severity of COVID-19

New nanoimmunoassay can detect anti–SARS-CoV-2 antibodies in ultralow-volume blood samples

Researchers examine how neighborhood and social network affect binge drinking among adults

Absence of key gene causes severe hearing loss

Using ultrasound and RNA-loaded nanoparticles to deliver potent medicine to brain tumors

CFTR modulator can be safe, well-tolerated for younger children with common form of cystic fibrosis

Supervised rehabilitation program can help patients with lasting symptoms of COVID-19

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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