Amino Acid News and Research

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Amino Acid is one of several molecules that join together to form proteins. There are 20 common amino acids found in proteins.

A study on the evolution of avian coronavirus escape mutants in vitro

A recent study included an in vitro assessment of the effect of antibody titers and vaccine combinations on the emergence of escape mutants of AvCoV.

28 Feb 2022

Study finds Omicron sublineage BA.2 is less pathogenic in rodent models than prior SARS-CoV-2 variants

Researchers evaluated the pathogenicity and replication potential of SARS-CoV-2 VOC Omicron lineage, BA.2 in immunocompetent mice and hamsters.

28 Feb 2022

Altered microbiomes in SARS-CoV-2 infection pose threat of antibiotic resistance

A new study discusses changes in the microbiota of various parts of the body with SARS-CoV-2 infection.

27 Feb 2022

Unexpected discovery could open the door to new treatment for small-cell lung cancer

An unexpected discovery at UVA Cancer Center has allowed scientists to halt the development of small-cell lung cancer in lab mice, and the surprise finding could open the door to a new treatment approach in people.

25 Feb 2022

Should SARS-CoV-2 Omicron be considered a serotype?

A recent article provides evidence for and against the hypothesis of SARS-CoV-2 serotypes.

24 Feb 2022

MIT chemists develop a novel way to synthesize himastatin

Chemists at MIT have developed a novel way to synthesize himastatin, a natural compound that has shown potential as an antibiotic.

24 Feb 2022

Exploring the potential of mosaic RBD nanoparticles to fight SARS-CoV-2

Researchers explore the potential of mosaic receptor-binding domain nanoparticles in protective immunity against SARS-CoV-2

22 Feb 2022

New approach for extensive screening of monoclonal antibody clones against multiple myeloma cells

Multiple myeloma (MM) is a largely incurable cancer of plasma cells with an extremely poor prognosis. However, investigators from Japan have recently found that a common component of amino acid transporters, CD98 heavy chain, represents an effective monoclonal antibody target in treating MM.

22 Feb 2022

Discovery could lead to new treatment approach for people with alcohol-associated liver disease

Investigators at Cedars-Sinai have uncovered a new pathway that helps explain how consuming too much alcohol causes damage to the liver, specifically mitochondrial dysfunction in alcohol-associated liver disease.

22 Feb 2022

Research shows the impact of accessory genes deletion in SARS-CoV-2 evolution

In a recent study published in the journal PLoS ONE, researchers investigated the effect of genetic variability based on accessory gene deletions on severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission and the clinical severity of coronavirus disease 2019 (COVID-19).

22 Feb 2022

Study explores efficacy of mRNA vaccine booster doses during the SARS-CoV-2 Omicron wave

Researchers evaluated the efficacy of an mRNA vaccine booster dose against severe acute respiratory syndrome coronavirus-2 during the Omicron surge.

18 Feb 2022

Impact of several ACE2 coding missense variants and their effect on ACE2 protein subcellular localization and trafficking

Researchers investigated the connecting link between viral genetic variability and clinical heterogeneity of COVID-19 by analyzing the effect of several missense mutations on the ACE2 receptor coding sequence.

18 Feb 2022

Novel blood biomarkers can potentially predict melanoma patients' response to immunotherapy

Melanoma, a type of skin cancer, is often curable when detected and treated in its early stages. However, the disease can rapidly spread to other organs in the body and become deadly. According to the American Cancer Society, more than 7,600 people die of the disease each year in the United States.

17 Feb 2022

Ensitrelvir, a novel SARS-CoV-2 antiviral

S-217622 reduces the viral load and help alleviate the severity of SARS-CoV-2 in infected hamsters.

17 Feb 2022

Research shows alterations in transfer RNAs at the epigenetic level in cancer

A recently published paper in the journal Molecular Cancer by the group of Dr. Manel Esteller, Director of the Josep Carreras Leukaemia Research Institute, ICREA Research Professor and Genetics Chairman at the University of Barcelona, shows that transfer RNAs for certain amino acids are altered at the epigenetic level in some types of cancer, expressing it in an exaggerated manner in some cases and being deficient in others.

17 Feb 2022

A novel consensus-based computational pipeline that reliably predicts hACE2-RBD binding affinity

Researchers developed a novel computational model to predict the binding affinity between the hACE2 receptor and the RBD of S protein of SARS-CoV-2.

17 Feb 2022

Study suggests tea polyphenols may modulate COVID-19 via intestinal microbiota

A new study discusses the state of current knowledge about the potential use of tea polyphenols in the prevention and treatment of COVID-19.

16 Feb 2022

Prediction of SARS-CoV-2 epitope candidates for future vaccines

Researchers identify and investigate the presence and evolution of the SARS-CoV-2 N and S glycoprotein proteins.

15 Feb 2022

Antiviral activity assessment of remdesivir against 10 current and former SARS-CoV-2 variant clinical isolates

A new study published demonstrated the in vitro potencies of RDV and GS-441524 through PRA, and nucleoprotein ELISA against SARS-CoV-2 and other VOC/VOIs isolates with specific substitutions in Nsp12.

15 Feb 2022

Study explores the generation of SARS-CoV-2 Omicron Spike DNA construct using multiple site-targeted mutagenesis

In a new study, a team of researchers demonstrated multiple site-directed mutagenesis as an efficient, easy, and more economically viable alternative to commercial gene synthesis to highlight how specific residues can contribute to the molecular structure and functioning of proteins.

15 Feb 2022

Amino Acid News and Research

Further Reading

A study on the evolution of avian coronavirus escape mutants in vitro

Study finds Omicron sublineage BA.2 is less pathogenic in rodent models than prior SARS-CoV-2 variants

Altered microbiomes in SARS-CoV-2 infection pose threat of antibiotic resistance

Unexpected discovery could open the door to new treatment for small-cell lung cancer

Should SARS-CoV-2 Omicron be considered a serotype?

MIT chemists develop a novel way to synthesize himastatin

Exploring the potential of mosaic RBD nanoparticles to fight SARS-CoV-2

New approach for extensive screening of monoclonal antibody clones against multiple myeloma cells

Discovery could lead to new treatment approach for people with alcohol-associated liver disease

Research shows the impact of accessory genes deletion in SARS-CoV-2 evolution

Study explores efficacy of mRNA vaccine booster doses during the SARS-CoV-2 Omicron wave

Impact of several ACE2 coding missense variants and their effect on ACE2 protein subcellular localization and trafficking

Novel blood biomarkers can potentially predict melanoma patients' response to immunotherapy

Ensitrelvir, a novel SARS-CoV-2 antiviral

Research shows alterations in transfer RNAs at the epigenetic level in cancer

A novel consensus-based computational pipeline that reliably predicts hACE2-RBD binding affinity

Study suggests tea polyphenols may modulate COVID-19 via intestinal microbiota

Prediction of SARS-CoV-2 epitope candidates for future vaccines

Antiviral activity assessment of remdesivir against 10 current and former SARS-CoV-2 variant clinical isolates

Study explores the generation of SARS-CoV-2 Omicron Spike DNA construct using multiple site-targeted mutagenesis

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Industry Focus eBook - Analytical Chemistry (3rd edition)

Industry Focus eBook - Microbiome (1st edition)

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