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West African countries must increase COVID-19 vaccination rates to achieve population-level immunity

West African nations need to drastically ramp up their COVID-19 vaccination programmes by factor of 10 if they are to reach at least 60% coverage by 2022 and achieve the population level immunity needed to bring the pandemic under control in Africa and elsewhere, indicates an analysis published in the open access journal BMJ Global Health.

15 Dec 2021

Severity of SARS-CoV-2 compared to other human coronaviruses in children

Researchers observed that symptom presentation of SARS-CoV-2 infections at the community level was very similar to that of endemic human coronavirus infections.

14 Dec 2021

Novel breathalyzer relies on viral RNA detection to diagnose SARS-CoV-2

In a new study in The Journal of Molecular Diagnostics, published by Elsevier, investigators report on the design and testing of a breathalyzer, known as the Bubbler, that relies on viral RNA detection to diagnose SARS-CoV-2.

13 Dec 2021

Impact of tumor environments on susceptibility and course of disease in those infected with SARS-CoV-2

A review assessed the impact of "hot" vs. "cold" immune/tumor environments (and associated therapies) on susceptibility and disease course in subjects with these two types of tumors and infected with SARS-CoV-2 to decipher the mechanisms that drive these adverse outcomes in COVID-19 infected cancer patients.

13 Dec 2021

Study suggests pre-existing human common cold coronavirus antibodies hinder SARS-CoV-2 immunity

In this study cohort, SARS-CoV-2 infections were confirmed via the RT-PCR test.

13 Dec 2021

Seasonal coronaviruses may help estimate SARS-CoV-2 reinfection risk

New research suggests that common human coronaviruses, such as those that cause the common cold, could also shed light on the patterns of SARS-CoV-2 reinfection.

13 Dec 2021

UCLA research points the way towards a longer-lasting COVID vaccine

Researchers at the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA have identified rare, naturally occurring T cells that are capable of targeting a protein found in SARS-CoV-2 and a range of other coronaviruses.

11 Dec 2021

Positive results from Phase 3 study of Medicago’s plant-based COVID-19 vaccine candidate announced

Medicago, a biopharmaceutical company headquartered in Quebec City, and GlaxoSmithKline today announce positive efficacy and safety results from the global Phase 3 placebo-controlled efficacy study of Medicago’s plant-based COVID-19 vaccine candidate in combination with GSK’s pandemic adjuvant, conducted in over 24,000 subjects, adults 18 years and above, across six countries.

9 Dec 2021

Community mask usage reduces symptomatic COVID seroprevalence in Bangladesh

A new Science preprint explores the effectiveness of universal masking in reducing the incidence of symptomatic disease.

7 Dec 2021

SARS-CoV-2 S2 immunization as a pan-coronavirus vaccine approach

A new mouse model suggests that prior HCoV-OC43 S immunity primes neutralising antibody responses to otherwise subimmunogenic SARS-CoV-2 S exposure as well as promotes S2-targeting antibody responses.

6 Dec 2021

A tale of two Medicaid expansions: Oklahoma jumps in, while Missouri lags

Temp worker James Dickerson applied for Medicaid because it will be cheaper than his current health plan. Home health aide Sharon Coleman looks forward to having coverage that will cover a hospital stay. Incoming medical student Danielle Gaddis no longer worries a trip to the doctor will leave her in debt.

3 Dec 2021

Special collection of articles highlights China's response to covid-19

Today, The BMJ is launching a special collection of articles on China's response to covid-19 - what it was, how it worked, why traditional public health measures played such a vital role, and how other countries can learn from this experience to protect their populations, in particular in future pandemics.

2 Dec 2021

Freeze-dried liposomes could be used in potential COVID-19 vaccines

Things that are freeze-dried: Astronaut food. Emergency rations. And, just maybe, some future COVID-19 vaccines.

1 Dec 2021

Deactivating the cancer-causing protein by cutting off other proteins that activate it

In a line of dominos, if you take out a single piece, the last one will never fall. Similarly, a lot of pieces have to line up and be pushed at the same time in a cell to result in cancer.

1 Dec 2021

Impact of partial lockdown on breaking COVID-19 fourth wave in Bavaria

An agent-based simulator was used to determine the historical course of COVID-19 and to analyze the effectiveness of lockdown.

1 Dec 2021

Review highlights oncolytic viruses with remarkable ability to destroy cancer cells

With the world still in the grip of a devastating pandemic, it's hard to imagine viruses as something other than hostile enemies to be vanquished.

30 Nov 2021

Northwestern researchers continue to tackle every facet of COVID-19 pandemic

As the COVID-19 pandemic nears the two-year mark, Northwestern Medicine scientists continue to tackle every facet of the disease, from investigating coronavirus vaccines' potential for providing immunity against similar coronaviruses to developing novel rapid antigen-based tests and examining disparities in COVID-19 case and mortality rates in Chicago.

30 Nov 2021

With federal covid sick leave gone, workers feel pressure to show up at work

Economists and public health experts alike say paid sick leave is an essential tool — like testing, masks and vaccines — in the effort to prevent covid-19 infection and keep workplaces safe.

30 Nov 2021

Cytomegalovirus herpesvirus can accelerate the decline of the immune system, study finds

A research team at the University of Córdoba is studying the alterations that occur in the immune system's T lymphocytes with respect to age and in relation to the cytomegalovirus herpesvirus.

29 Nov 2021

AVAT, Africa CDC and COVAX release statement regarding donations of COVID-19 vaccines to Africa

Building on lessons learned from our collective experience with dose donations over the past several months, the African Vaccine Acquisition Trust, the Africa Centres for Disease Control and Prevention and COVAX wish to draw the attention of the international community to the situation of donations of COVID-19 vaccines to Africa, and other COVAX participating economies, particularly those supported by the Gavi COVAX Advance Market Commitment.

29 Nov 2021

Cold News and Research

West African countries must increase COVID-19 vaccination rates to achieve population-level immunity

Severity of SARS-CoV-2 compared to other human coronaviruses in children

Novel breathalyzer relies on viral RNA detection to diagnose SARS-CoV-2

Impact of tumor environments on susceptibility and course of disease in those infected with SARS-CoV-2

Study suggests pre-existing human common cold coronavirus antibodies hinder SARS-CoV-2 immunity

Seasonal coronaviruses may help estimate SARS-CoV-2 reinfection risk

UCLA research points the way towards a longer-lasting COVID vaccine

Positive results from Phase 3 study of Medicago’s plant-based COVID-19 vaccine candidate announced

Community mask usage reduces symptomatic COVID seroprevalence in Bangladesh

SARS-CoV-2 S2 immunization as a pan-coronavirus vaccine approach

A tale of two Medicaid expansions: Oklahoma jumps in, while Missouri lags

Special collection of articles highlights China's response to covid-19

Freeze-dried liposomes could be used in potential COVID-19 vaccines

Deactivating the cancer-causing protein by cutting off other proteins that activate it

Impact of partial lockdown on breaking COVID-19 fourth wave in Bavaria

Review highlights oncolytic viruses with remarkable ability to destroy cancer cells

Northwestern researchers continue to tackle every facet of COVID-19 pandemic

With federal covid sick leave gone, workers feel pressure to show up at work

Cytomegalovirus herpesvirus can accelerate the decline of the immune system, study finds

AVAT, Africa CDC and COVAX release statement regarding donations of COVID-19 vaccines to Africa

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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