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Study finds dramatic increase in nonmedical use of prescription opioids in the U.S.

Nonmedical use of prescription opioids more than doubled among adults in the United States from 2001-2002 to 2012-2013, based on a study from the National Institute on Alcohol Abuse and Alcoholism, part of the National Institutes of Health. Nearly 10 million Americans, or 4.1 percent of the adult population, used opioid medications in 2012-2013 a class of drugs that includes OxyContin and Vicodin, without a prescription or not as prescribed (in greater amounts, more often, or longer than prescribed) in the past year.

23 Jun 2016

Study captures interactions of HIV-infected immune cells in living animal

By watching brightly glowing HIV-infected immune cells move within mice, researchers at the Icahn School of Medicine at Mount Sinai have shown how infected immune cells latch onto an uninfected sister cell to directly transmit newly minted viral particles.

10 Jun 2016

Study sheds new light on the brain’s decision-making processes

Netflix binge-watching versus a hike in the woods. A cheeseburger versus kale salad. Fentanyl versus Tylenol. New UC research from the University California, Berkeley, suggests our brain activity could be influenced to make the healthier choice.

10 Jun 2016

U-M study compares early-use and longer-duration stimulant medication with nonstimulant therapy for ADHD

Youth who take Ritalin, Adderall or other stimulant medications for ADHD over an extended period of time early in life are no more at risk for substance abuse in later adolescence than teens without ADHD, according to a University of Michigan study.

9 Jun 2016

Chronic marijuana use can interrupt the brain's natural reward processes

Chronic marijuana use disrupts the brain's natural reward processes, according to researchers at the Center for BrainHealth at The University of Texas at Dallas.

8 Jun 2016

Short-term use of opioids implicated in protracted pain, new study finds

Painkillers such as morphine, oxycodone and methadone could actually prolong and increase pain even after only a few days’ use, according to research conducted on rats by scientists at the University of Colorado Boulder in the US.

31 May 2016

Brief opioid exposure can cause increase in chronic pain

The dark side of painkillers - their dramatic increase in use and ability to trigger abuse, addiction and thousands of fatal overdoses annually in the United States is in the news virtually every day.

31 May 2016

First buprenorphine implant for opioid dependence treatment gets FDA approval

The U.S. Food and Drug Administration today approved Probuphine, the first buprenorphine implant for the maintenance treatment of opioid dependence. Probuphine is designed to provide a constant, low-level dose of buprenorphine for six months in patients who are already stable on low-to-moderate doses of other forms of buprenorphine, as part of a complete treatment program.

27 May 2016

Parenting stress in women may affect sexual satisfaction of both partners

First-time parents are only somewhat satisfied with their sex lives according to Penn State health researchers who checked in with parents regularly after their baby was born. And one factor that appears to be reducing their sexual satisfaction is mothers' stress as a new parent.

27 May 2016

Marijuana use among teens declines despite widespread legalization

A survey of more than 216,000 adolescents from all 50 states indicates the number of teens with marijuana-related problems is declining. Similarly, the rates of marijuana use by young people are falling despite the fact more U.S. states are legalizing or decriminalizing marijuana use and the number of adults using the drug has increased.

25 May 2016

Closely related molecule can mimic effect of PKMzeta in mice

New research led by SUNY Downstate Medical Center shows that mice devoid of PKMzeta, a molecule previously identified by SUNY Downstate scientists as essential to memory formation and storage, recruit a closely related molecule, PKCiota/lambda, to make up for the missing PKMzeta.

18 May 2016

Specific gene links impulsive behavior to binge drinking in teens

From minor acts of rebellion such as bunking off school, to the more serious experimentation with illicit substances, the teenage years can be a stressful time for parents.

12 May 2016

Two statistically significant genetic variants may be linked to increased PTSD risk in veterans

In a massive analysis of DNA samples from more than 13,000 U.S. soldiers, scientists have identified two statistically significant genetic variants that may be associated with an increased risk of post-traumatic stress disorder (PTSD), an often serious mental illness linked to earlier exposure to a traumatic event, such as combat and an act of violence.

12 May 2016

Children of depressed parents more likely to have recurrent episodes of depression, poor outcomes in adulthood

The latest report from a 30-year study of families at high- and low-risk for depression reveals that the offspring of depressed parents have a higher risk for depression, morbidity and mortality that persists into middle age.

12 May 2016

Researchers find link between BPD and risk of STI/HIV in male inmates

Sexually transmitted infections (STI), including HIV, disproportionately affect incarcerated populations. In 2010, over 90% of the inmates living with HIV in U.S. prisons were men and the prevalence of STIs such as chlamydia, gonorrhea, and syphilis, continues to be much higher among male inmates as compared to the U.S. population at large.

11 May 2016

Majority of patients who misuse drugs and alcohol have chronic pain

With opioid addiction and prescription drug abuse considered one of the biggest public health threats of our time in the U.S., many are asking why so many Americans are struggling with addiction to illegal drugs and prescription medications. New research suggests that chronic pain may be part of the answer.

10 May 2016

Increasing ghrelin levels during hunger can negatively affect decision making capabilities

Never make a decision when you are hungry. The hormone ghrelin - that is released before meals and known to increase appetite - has a negative effect on both decision making and impulse control. Such were the results of a recently conducted study at Sahlgrenska University.

10 May 2016

Researchers examine role of neural circuit in making decisions

Choosing what shirt to buy, what to order for lunch or whether to go with the hearty red wine or the lighter white all involve assigning values to the options. A small brain structure plays a central role in the many decisions like this we make each day. But it hasn't been clear how a limited number of neurons in this small part of the brain can support an unlimited number of choices.

10 May 2016

High prevalence of depression alongside COPD can impact overall health, treatment effectiveness

Although there have been discussions about chronic obstructive pulmonary disease (COPD), a condition impacting 24 million Americans, and depression, there has been little research showing the impact depression has on patients with COPD. Two studies published in the April issue of the journal CHEST found one in four patients with COPD suffer from depressive symptoms, and if not treated, those symptoms can have a negative effect on their overall health and treatment effectiveness.

4 May 2016

Depression, anxiety co-occur in bipolar disorder patients following mania

Adults with bipolar disorder are just as likely to develop anxiety as depression following an episode of mania, according to data from a national survey of more than 34,000 adults. This finding, published today in Molecular Psychiatry, may expand our understanding of bipolar disorder to include anxiety.

4 May 2016