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UBC discovery may offer new treatment possibility for women with rare form of ovarian cancer

A recent finding by researchers at the BC Cancer Research Institute and the University of British Columbia may offer a new treatment possibility for people diagnosed with a rare and aggressive form of ovarian cancer.

26 Aug 2020

Advances in Virus Epigenetics

Growing evidence shows viruses exploit epigenetic processes to control their life cycles but epigentic regulation of viral infections is not fully understood.

From Chromatrap® - Porvair Sciences Ltd 25 Aug 2020

Researchers discover new mechanism for anticancer drug resistance in gastric cancer

A joint project led by Kumamoto University (Japan) has discovered a new mechanism for anticancer drug resistance in gastric cancer.

21 Aug 2020

Study identifies a novel regulatory pathway in bladder cancer

Researchers from Johns Hopkins University in collaboration with Insilico Medicine announce the publication of a new research paper titled "GULP1 regulates the NRF2-KEAP1 signaling axis in urothelial carcinoma" in Science Signaling.

20 Aug 2020

A metabolic enzyme shows great potential as target for immunotherapies

The metabolic enzyme IL4I1 (Interleukin-4-Induced-1) promotes the spread of tumor cells and suppresses the immune system.

20 Aug 2020

Acidic niche within lymph nodes plays integral role in regulating T cell activation

In the fight against cancer, the immune system is the first line of defense. The lymphatic system specifically is essential to protecting the body against foreign invaders.

19 Aug 2020

Multiplication of ecDNA genes present in many cancer types, drives poor patients outcomes

The multiplication of genes located in extrachromosomal DNA that have the potential to cause cancer drives poor patient outcomes across many cancer types, according to a Nature Genetics study published Aug. 17, 2020 by a team of researchers including Professors Vineet Bafna and Dr.Paul Mischel of the University of California San Diego and Professor Roel Verhaak of Jackson Laboratories.

17 Aug 2020

Genome analysis helps detect 568 genes that drive cancer

Analysis of the genomes of 28,000 tumors from 66 types of cancer has led to the identification of 568 cancer driver genes

17 Aug 2020

Targeting SARS-CoV-2 with off-the-shelf CAR-NK cells

The current COVID-19 pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continues to spread and cause disease and death in many countries even today. At present, there is no effective treatment. A recent study published on the preprint server bioRxiv in August 2020 reports the potential of a new class of drugs called CAR NK cells, which could be used off-the-shelf to treat this disease.

17 Aug 2020

Researchers develop implantable hydrogels based on plant polysaccharides

Far Eastern Federal University (FEFU) scientists have developed implantable hydrogels based on plant polysaccharides (pectins). They can play the role of an artificial extracellular matrix, a special network of molecules that fills the space between body cells.

14 Aug 2020

Researchers identify new mechanism that causes leukemia

Every year, 1.1 million new cases of blood cancers are diagnosed worldwide. Presently, chemotherapy remains the most common and effective course of treatment.

13 Aug 2020

Cardiovascular disease in COVID-19

The current COVID-19 pandemic is a primarily respiratory illness, manifesting with severe hypoxia and often progressing to acute respiratory distress syndrome (ARDS) and death. However, it is also known to be linked to a wide range of cardiovascular (CV) manifestations that are associated with a very poor prognosis.

13 Aug 2020

Fluorescent molecules in urine can help monitor malignant melanoma

What if you could simply provide a urine sample rather than undergo a painful surgical procedure to find out if your cancer was responding to treatment? It may seem too good to be true, but researchers at Pavol Jozef Šafárik University in Košice, Slovakia, have identified fluorescent molecules in urine that may allow patients with malignant melanoma to do just that.

11 Aug 2020

NSD2 enzyme protects against cellular senescence

Researchers from Kumamoto University in Japan have used comprehensive genetic analysis to find that the enzyme NSD2, which is known to regulate the actions of many genes, also works to block cell aging.

7 Aug 2020

New type of immunotherapy shows promise for advanced skin cancer

A new type of immunotherapy for the skin cancer malignant melanoma shows promising results. Three severely ill patients are now long-term survivors.

7 Aug 2020

Enzyme could play key role in treating cancer, autoimmune diseases in the airway

Findings from a research study, led by scientists at Henry Ford, published in the latest issue of Nature Communications suggest an enzyme could play an important role in the treatment of cancer and autoimmune diseases in the airway.

5 Aug 2020

Researchers identify targeted treatment strategy for malignant pleural mesothelioma

The reactivation of telomerase is a key mechanism in the unrestricted growth of cancer cells. Malignant pleural mesothelioma (MPM) is a form of cancer originating from the mesothelium, a cell layer covering the lungs and the inside of the chest wall.

30 Jul 2020

Combination of certain drugs can do more harm than good, shows study

A team of researchers at the Norwegian University of Science and Technology (NTNU) investigating how a certain type of drugs can kill cells has discovered that these drugs can do more harm than good when used in combination with other cancer treatments.

29 Jul 2020

Cancer-related care has decreased since the start of COVID-19

Research from the Sidney Kimmel Cancer Center - Jefferson Health (SKCC) found significant decreases nationwide in the number of patients being seen for cancer-related care as the COVID-19 pandemic progressed during the few first months of 2020.

28 Jul 2020

AI Therapeutics announces start of Phase II clinical trial of potential COVID-19 treatment

AI Therapeutics announced the start of Phase II clinical trial for the treatment of newly diagnosed COVID-19 patients in collaboration with Yale University.

27 Jul 2020

Malignant News and Research

UBC discovery may offer new treatment possibility for women with rare form of ovarian cancer

Advances in Virus Epigenetics

Researchers discover new mechanism for anticancer drug resistance in gastric cancer

Study identifies a novel regulatory pathway in bladder cancer

A metabolic enzyme shows great potential as target for immunotherapies

Acidic niche within lymph nodes plays integral role in regulating T cell activation

Multiplication of ecDNA genes present in many cancer types, drives poor patients outcomes

Genome analysis helps detect 568 genes that drive cancer

Targeting SARS-CoV-2 with off-the-shelf CAR-NK cells

Researchers develop implantable hydrogels based on plant polysaccharides

Researchers identify new mechanism that causes leukemia

Cardiovascular disease in COVID-19

Fluorescent molecules in urine can help monitor malignant melanoma

NSD2 enzyme protects against cellular senescence

New type of immunotherapy shows promise for advanced skin cancer

Enzyme could play key role in treating cancer, autoimmune diseases in the airway

Researchers identify targeted treatment strategy for malignant pleural mesothelioma

Combination of certain drugs can do more harm than good, shows study

Cancer-related care has decreased since the start of COVID-19

AI Therapeutics announces start of Phase II clinical trial of potential COVID-19 treatment

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How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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