Malignant News and Research

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Researchers develop breakthrough blood test for brain tumors

Genetic mutations that promote the growth of the most common type of adult brain tumors can be accurately detected and monitored in blood samples using an enhanced form of liquid biopsy developed by researchers at Massachusetts General Hospital.

14 Oct 2020

Study uncovers the mechanism behind bone marrow failure in Fanconi anemia

Fanconi anaemia (FA) is a genetic disease affecting small children characterized by bone-marrow failure, developmental abnormalities and predisposition to multiple forms of cancer.

14 Oct 2020

3D structural model of BAF complex modifies DNA architecture, provides clues on cancer

Scientists have created an unprecedented 3-dimensional structural model of a key molecular "machine" known as the BAF complex, which modifies DNA architecture and is frequently mutated in cancer and some other diseases.

14 Oct 2020

Researchers are developing a new class of compounds against various cancers

Researchers at The Wistar Institute and collaborators from the University of Notre Dame are developing anticancer compounds targeting a pathway of the endoplasmic reticulum (ER) stress response implicated in the development of multiple myeloma (MM), chronic lymphocytic leukemia (CLL) and lymphoma.

14 Oct 2020

Study shows how mutations in VAV1 gene may promote T-cell tumors in experimental mice

Life is an exquisite orchestration of growth and change, with checks and balances that fine-tune complex entwined interactions, both intrinsic and external.

12 Oct 2020

Developing a precision 'Trojan Horse' nanotherapy to treat breast cancer

With a nearly $2.6 million grant from the National Institutes of Health, Michigan State University researchers are using nanoscopic particles to turn the body's own cells into weapons that cancer won't see coming.

9 Oct 2020

Hypoxic exosomes promote stemness in EWS sarcoma, indicates study

The cover for issue 40 of Oncotarget features Figure 5, "miR-210 silences the proapoptosis member CASP8AP2," by Kling, et al. which reported that hypoxic Ewing's sarcoma cells release exosomes that promote sphere formation, a stem-like phenotype, in EWS cells by enhancing survival.

9 Oct 2020

Study: Thymoquinone selectively kills prostate cancer cells at advanced stages

The compound thymoquinone (TQ) selectively kills prostate cancer cells at advanced stages, according to a new study published in Oncogene.

8 Oct 2020

UM associate professor wins multiple awards for ear, skin science

University of Montana scientist Monica Serban is on a research roll. In recent months the UM associate professor and her team have earned three awards totaling $3.9 million in funding to study preventing hearing loss among U.S. troops, combating ear infections and creating a synthetic skin product.

6 Oct 2020

Survival probabilities are higher in patients who underwent complex pancreatic surgery

For certain surgical procedures, can a correlation be shown between the volume of services provided per hospital and the quality of treatment results?

6 Oct 2020

Direction and type of the force acting on a cell can alter gene expression

Tissues and cells in the human body are subjected to a constant push and pull - strained by other cells, blood pressure and fluid flow, to name a few.

1 Oct 2020

Researchers unravel new mechanism of cell survival in chronic lymphocytic leukemia

Researchers at The Wistar Institute unraveled a mechanism employed by chronic lymphocytic leukemia (CLL) cells for their survival.

30 Sep 2020

Skoltech researchers identify new panel of potential biomarkers for liver cancer diagnosis

A group of Skoltech scientists led by a Skoltech and MSU professor Olga Dontsova discovered a novel liver-specific non-coding RNA.

30 Sep 2020

New FLASH technique could revolutionize radiation therapy for cancer patients

For the first time, researchers at the Centre for Proton Therapy at the Paul Scherrer Institute PSI in Switzerland have tested ultrafast, high-dose irradiation with protons.

28 Sep 2020

Researchers decipher how the immune system memorizes pathogens after an infection

The immune system will memorize the pathogen after an infection and can therefore react promptly after reinfection with the same pathogen. Now, scientists at the University of Würzburg have deciphered new details of this process.

28 Sep 2020

Interdisciplinary team wins NIH grant to develop a device for early oral cancer detection

Mouth lesions are among the main early indicators of oral cancer, but determining whether a sore is actually malignant typically involves painful, costly biopsies.

28 Sep 2020

Biomarker candidates could aid in earlier diagnosis of mesothelioma

Mesothelioma is a deadly cancer mainly caused by exposure to asbestos fibers. Unfortunately, mesothelioma is generally diagnosed at an already advanced stage and none of the therapeutic strategies tried so far is able to eradicate the disease.

24 Sep 2020

Discovery could help enhance the effectiveness of immunotherapy against melanoma

Researchers at the University of Bern have discovered a mechanism in the body’s own immune system which is responsible for the maturation and activation of immune cells.

19 Sep 2020

Hannover and Rostock team up to develop non-invasive optical melanoma diagnostics

Leibniz University Hannover and Rostock University Medical Center receive funding for the development of non-invasive optical melanoma diagnostics.

17 Sep 2020

PET/MRI reduces radiation exposure, improves lesion detectability in select cancers

A single-center observational study of more than 1,000 oncological examinations has demonstrated that positron emission tomography/magnetic resonance imaging (PET/MRI) facilitates cancer staging as well as PET/computed tomography (PET/CT) and improves lesion detectability in select cancers, potentially helping to promote fast, efficient local and whole-body staging in one step.

17 Sep 2020

Malignant News and Research

Researchers develop breakthrough blood test for brain tumors

Study uncovers the mechanism behind bone marrow failure in Fanconi anemia

3D structural model of BAF complex modifies DNA architecture, provides clues on cancer

Researchers are developing a new class of compounds against various cancers

Study shows how mutations in VAV1 gene may promote T-cell tumors in experimental mice

Developing a precision 'Trojan Horse' nanotherapy to treat breast cancer

Hypoxic exosomes promote stemness in EWS sarcoma, indicates study

Study: Thymoquinone selectively kills prostate cancer cells at advanced stages

UM associate professor wins multiple awards for ear, skin science

Survival probabilities are higher in patients who underwent complex pancreatic surgery

Direction and type of the force acting on a cell can alter gene expression

Researchers unravel new mechanism of cell survival in chronic lymphocytic leukemia

Skoltech researchers identify new panel of potential biomarkers for liver cancer diagnosis

New FLASH technique could revolutionize radiation therapy for cancer patients

Researchers decipher how the immune system memorizes pathogens after an infection

Interdisciplinary team wins NIH grant to develop a device for early oral cancer detection

Biomarker candidates could aid in earlier diagnosis of mesothelioma

Discovery could help enhance the effectiveness of immunotherapy against melanoma

Hannover and Rostock team up to develop non-invasive optical melanoma diagnostics

PET/MRI reduces radiation exposure, improves lesion detectability in select cancers

Event guide: 4th Extra-Hepatic Lipid-Based Nanoparticles Delivery Summit eBook

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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