Proliferation News and Research

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What role do dietary lipids play in the gut-brain axis in type 2 diabetes mellitus?

Researchers examined the significance of dietary lipids in the gut-brain axis of individuals with T2DM.

4 Apr 2023

Endothelial deletion of the Wt1 gene affects coronary vessel formation and myocardial development

How is the mammals' heart formed? What role do endothelial cells play? Do the same pathways and genes involved in the formation of the embryonic heart also play a role in repair processes?

4 Apr 2023

Study assesses the cellular and molecular immunopathology of post-COVID lung disease

Researchers assessed the cellular and molecular level immunopathology of PCLD.

4 Apr 2023

Can the Mediterranean diet and physical exercise improve the quality of life for cancer patients?

Researchers reviewed existing literature on the benefits of adopting Mediterranean diets against inflammatory conditions and cancer.

3 Apr 2023

New review examines link between HDLC and different types of cancer

Researchers summarized studies on the association between high-density lipoprotein cholesterol and different types of cancer

29 Mar 2023

Diverse subset of T-cell clones plays a role in the antitumor effects of immune checkpoint inhibitors

Immune checkpoint inhibitors (ICIs) are widely sought after for the treatment of different types of cancers. Unfortunately, only 20–30% patients with cancer respond to ICI treatment.

29 Mar 2023

Study investigates how loss of angulin-1/LSR affects the malignancy of lung adenocarcinoma

A new research paper was published in Oncotarget's Volume 14 on March 24, 2023, entitled, "Downregulation of angulin-1/LSR induces malignancy via upregulation of EGF-dependent claudin-2 and TGF-β-dependent cell metabolism in human lung adenocarcinoma A549 cells."

29 Mar 2023

Study finds correlations between how and which organ systems are affected in individuals with new epileptic disorder

A recent study from Texas Children's Hospital and Baylor College of Medicine has expanded the clinical spectrum of a new epileptic disorder called Intellectual Developmental Disorder with Macrocephaly, Seizures, and Speech Delay (IDDMSSD) with the identification of the first recurrently affected residue identified in the protein kinase domain of PAK1 protein.

29 Mar 2023

Mouse avatars could help design more effective and personalized therapies for multiple myeloma

An international group of researchers, led by Dr. José Ángel Martínez-Climent at the Cima University of Navarra, has created mouse avatars of patients with multiple myeloma to study and develop personalized treatments against this blood cancer, the second most frequent hematological cancer and incurable in most cases.

29 Mar 2023

Clockwork in cancer: the importance of the circadian rhythm in the formation and progression of tumors

Researchers reviewed the importance of the circadian rhythm in the formation and progression of tumors.

29 Mar 2023

The connection between gut microbiota, the gut–brain axis, and brain aging: can polyphenols have an impact?

A review published in the Antioxidants journal aimed to understand the impact of gut microbiota on brain aging.

28 Mar 2023

CD9-positive exosomes inhibit the growth of malignant melanoma, study suggests

Malignant melanoma is a relatively aggressive type of skin cancer. When detected early, it is usually treatable by surgical resection only, but metastases develop often spreading to distant areas.

28 Mar 2023

Circadian rhythms govern cancer progression and metastasis

Your circadian rhythm doesn't just govern your sleeping schedule; it can also impact cancer development, diagnosis, and treatment.

24 Mar 2023

Candida auris escapes innate immunity through metabolic reprogramming

A team of scientists from Australia and Israel demonstrates that Candida auris, a fungus associated with life-threatening and drug-resistant infections, escapes the host's innate immune response by destroying macrophages through metabolic reprogramming. The fungus is also capable of escaping antimicrobial inflammatory response.

23 Mar 2023

A lot of thought, little action: Proposals about mental health go unheeded

Thousands of people struggle to access mental health services in Florida. The treatment system is disjointed and complex.

22 Mar 2023

Tetravalent COVID vaccine provides broad antibody responses against SARS-CoV-2 variants in animal model

In a recent study posted to the bioRxiv* preprint server, researchers in Italy and the United States evaluated the efficacy and immunogenicity of an adjuvanted tetravalent severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S) protein subunit 1 (S1) COVID-19 vaccine.

21 Mar 2023

Researchers identify the cellular glitches underlying a rare genetic disorder

The cellular glitches underlying a rare genetic disorder called activated PI3K Delta syndrome 2 (APDS2) have been identified by researchers at the Garvan Institute of Medical Research. The disorder is caused by genetic variations that disrupt immune cell signaling through a protein called PI3K.

21 Mar 2023

Proliferation News and Research

What role do dietary lipids play in the gut-brain axis in type 2 diabetes mellitus?

Endothelial deletion of the Wt1 gene affects coronary vessel formation and myocardial development

Study assesses the cellular and molecular immunopathology of post-COVID lung disease

Can the Mediterranean diet and physical exercise improve the quality of life for cancer patients?

New review examines link between HDLC and different types of cancer

Diverse subset of T-cell clones plays a role in the antitumor effects of immune checkpoint inhibitors

Study investigates how loss of angulin-1/LSR affects the malignancy of lung adenocarcinoma

Study finds correlations between how and which organ systems are affected in individuals with new epileptic disorder

Mouse avatars could help design more effective and personalized therapies for multiple myeloma

Clockwork in cancer: the importance of the circadian rhythm in the formation and progression of tumors

The connection between gut microbiota, the gut–brain axis, and brain aging: can polyphenols have an impact?

CD9-positive exosomes inhibit the growth of malignant melanoma, study suggests

Circadian rhythms govern cancer progression and metastasis

Candida auris escapes innate immunity through metabolic reprogramming

A lot of thought, little action: Proposals about mental health go unheeded

Tetravalent COVID vaccine provides broad antibody responses against SARS-CoV-2 variants in animal model

Researchers identify the cellular glitches underlying a rare genetic disorder

Review explores trehalose's effects on metabolism and gut microflora

Ipsilateral vaccination improves response to second dose of COVID-19 vaccine

Study sheds new insight into the dynamics of neural stem cell niche

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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