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Durata Therapeutics completes dalbavancin Phase 3 trials on ABSSSI

Durata Therapeutics today announced results from its QT study of the company's lead product candidate, dalbavancin. Dalbavancin is currently under investigation in two ongoing, global, Phase 3 clinical trials for the treatment of acute bacterial skin and skin structure infections (ABSSSI).

11 Sep 2012

Methodist Hospital develops new technology to rapidly detect drug-resistant TB

Technology developed by scientists at The Methodist Hospital Research Institute could halve the time it takes to diagnose tuberculosis infection, and also tell doctors in a day or two whether the bacteria are drug resistant -- a process that currently takes weeks. Initial tests of the device were recently described in Scientific Reports, a Nature online journal.

11 Sep 2012

Eaton plans to begin development of transdermal patch delivery system for Tropine 3

Eaton Scientific Systems, Ltd. a wholly-owned subsidiary of Pristine Solutions, Inc. is pleased to announce that the Company plans to begin development of a transdermal patch delivery system for Tropine 3, a patent pending novel indication of homatropine for non-hormonal treatment of hot flashes in pre-menopausal, peri-menopausal, and post-menopausal women.

11 Sep 2012

'No malignancy risk' with biologic response modifiers

Rheumatoid arthritis patients treated with biologic response modifiers for at least 6 months do not have a greater risk for malignancy than those given other disease-modifying drugs or placebo, conclude US and Spanish researchers.

10 Sep 2012

Atox Bio AB103 for Necrotizing Soft Tissue Infections granted FDA Fast Track designation

Atox Bio, a clinical stage biotechnology company engaged in the development of novel immunemodulators for severe infections in critically ill patients, announced today that the U.S. Food and Drug Administration has granted Fast Track designation to AB103, its lead product, currently in development for the treatment of Necrotizing Soft Tissue Infections (NSTI).

10 Sep 2012

Surprising new roles for angiotensin converting enzyme

At the 1st ECRC "Franz-Volhard" Symposium on September 7, 2012 at the Max Delbr-ck Center for Molecular Medicine (MDC) in Berlin-Buch, Professor Ken Bernstein reported that in mice an excess of ACE led to a much stronger immune response than usual.

10 Sep 2012

Skin, immune system play an important role in regulating sodium balance and hypertension

High blood pressure is responsible for many cardiovascular diseases that are the leading cause of death in industrialized countries. High salt intake has long been considered a risk factor, but not every type of high blood pressure is associated with high salt intake. This has puzzled scientists for a long time. However, new findings by Professor Jens Titze (Vanderbilt University, Nashville, Tennessee, USA and the University of Erlangen) now point to previously unknown mechanisms.

10 Sep 2012

Novel surgical technique removes invasive facial tumor, recreates functional lower jaw and mouth

Using a novel surgical approach, it's possible to rebuild a functional lower jaw and mouth, and preserve a patient's ability to eat and speak after removing an invasive facial tumor, according to a new report from Henry Ford Hospital in Detroit.

10 Sep 2012

Scientists report first comprehensive genetic analysis of lung squamous cell carcinoma

A nationwide consortium of scientists has reported the first comprehensive genetic analysis of squamous cell carcinoma of the lung, a common type of lung cancer responsible for about 400,000 deaths each year.

10 Sep 2012

Nano biosensor measures and analyzes glucose without needle pricks

Pricking a finger everyday is just part of everyday life for many diabetes patients. A non-invasive measurement approach could release them from the constant pain of pin pricks. The linchpin is a biosensor engineered by Fraunhofer researchers: A tiny chip combines measurement and digital analysis - and can be radioed to a mobile device.

7 Sep 2012

Therapeutic targets for pemphigus vulgaris discovered

Researchers have identified the primary target of the autoantibodies found in the serum of patients with the blistering skin disorder pemphigus vulgaris.

7 Sep 2012

Germline BAP1 mutations associated with novel cancer syndrome

University of Hawai'i Cancer Center researchers have discovered germline BAP1 mutations are associated with a novel cancer syndrome characterized by malignant mesothelioma, uveal melanoma, cutaneous melanoma and atypical melanocytic tumors. Germline mutations are hereditary gene defects that are present in every cell.

7 Sep 2012

Parents' concern about melanoma does not make them keep their kids indoors

Pick your poison: sun exposure that leads to skin cancer or low physical activity that leads to obesity? In fact, a University of Colorado Cancer Center study published this week in the journal Preventing Chronic Disease shows that parents' concern about skin cancer doesn't make them keep their kids indoors.

7 Sep 2012

Melanoma manifests differently in children than in adults

Melanoma, newly diagnosed in more than 76,000 Americans in 2011, is the most common and dangerous form of skin cancer. Melanoma is rare in children, accounting for 1 to 4 percent of all melanoma cases and just 3 percent of pediatric cancers. Just as adult cases of melanoma are increasing, pediatric melanoma is rising at the rate of 1 to 4 percent per year.

7 Sep 2012

Hebrew University researcher develops anti-inflammatory and anti-allergic family of drugs

A synthetic, anti-inflammatory and anti-allergic family of drugs to combat a variety of illnesses while avoiding detrimental side effects has been developed by a Hebrew University of Jerusalem researcher.

7 Sep 2012

Researchers turn skin cells into embryonic Sertoli-like cells

Using a stepwise trans-differentiation process, Whitehead Institute researchers have turned skin cells into embryonic Sertoli-like cells.

7 Sep 2012

Durata completes target enrollment in dalbavancin Phase 3 trials for abSSSI

Durata Therapeutics today announced that it has completed its target enrollment for DISCOVER 1 ("Dalbavancin for Infections of the Skin COmpared to Vancomycin at an Early Response"), one of two ongoing, global, Phase 3 clinical trials of Durata's lead product candidate, dalbavancin, under investigation for the treatment of acute bacterial skin and skin structure infections (abSSSI).

7 Sep 2012

Study sheds light on why women gain fat following menopause

A high-fat diet triggers chemical reactions in female mice that could explain why women are more likely than men to gain fat in the abdomen after eating excess saturated fat, new research suggests. The study also sheds light on why women gain fat following menopause.

6 Sep 2012

Exposure to phthalates increases risk of asthma-related airway inflammation in children

Children exposed to diethyl phthalate (DEP) and butylbenzyl phthalate (BBzP)-phthalate chemicals commonly found in personal care and plastic products-have elevated risk of asthma-related airway inflammation, according to researchers at Columbia Center for Children's Environmental Health (CCCEH) at the Mailman School of Public Health.

6 Sep 2012

Antibiotics: facts and fictions: an interview with Dr Philippa Binns, clinical adviser at NPS MedicineWise

Antibiotics are medicines used to treat infections or diseases caused by bacteria, such as some respiratory tract infections (including pneumonia and whooping cough), urinary tract infections, skin infections and infected wounds.

6 Sep 2012

Skin News and Research

Durata Therapeutics completes dalbavancin Phase 3 trials on ABSSSI

Methodist Hospital develops new technology to rapidly detect drug-resistant TB

Eaton plans to begin development of transdermal patch delivery system for Tropine 3

'No malignancy risk' with biologic response modifiers

Atox Bio AB103 for Necrotizing Soft Tissue Infections granted FDA Fast Track designation

Surprising new roles for angiotensin converting enzyme

Skin, immune system play an important role in regulating sodium balance and hypertension

Novel surgical technique removes invasive facial tumor, recreates functional lower jaw and mouth

Scientists report first comprehensive genetic analysis of lung squamous cell carcinoma

Nano biosensor measures and analyzes glucose without needle pricks

Therapeutic targets for pemphigus vulgaris discovered

Germline BAP1 mutations associated with novel cancer syndrome

Parents' concern about melanoma does not make them keep their kids indoors

Melanoma manifests differently in children than in adults

Hebrew University researcher develops anti-inflammatory and anti-allergic family of drugs

Researchers turn skin cells into embryonic Sertoli-like cells

Durata completes target enrollment in dalbavancin Phase 3 trials for abSSSI

Study sheds light on why women gain fat following menopause

Exposure to phthalates increases risk of asthma-related airway inflammation in children

Antibiotics: facts and fictions: an interview with Dr Philippa Binns, clinical adviser at NPS MedicineWise

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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