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Designing effective multidrug-resistant-TB treatments based on DNA sequencing

Globally, tuberculosis is the most common bacterial infectious disease leading to death. The pathogen causing tuberculosis, Mycobacterium tuberculosis, has a number of peculiarities. One is that it is growing very slowly.

3 May 2021

Chemotherapy drugs delivered via nanoparticles could improve bowel cancer survival rates

Bowel cancer survival rates could be improved if chemotherapy drugs were delivered via tiny nanoparticles to the diseased organs rather than oral treatment.

3 May 2021

New gene therapy restores dystrophin protein in patients with Duchenne muscular dystrophy

UT Southwestern scientists successfully employed a new type of gene therapy to treat mice with Duchenne muscular dystrophy (DMD), uniquely utilizing CRISPR-Cas9-based tools to restore a large section of the dystrophin protein that is missing in many DMD patients.

3 May 2021

Pulmonary endarterectomy improves outcomes in patients with segmental disease

A new study, presented today at the AATS 101st Annual Meeting, found that patients treated surgically for segmental Chronic Thromboembolic Pulmonary Hypertension (CTEPH) had excellent outcomes with the vast majority doing very well in the long term without any additional treatment other than surgery.

3 May 2021

New approach could revolutionize the treatment of liver diseases

Researchers from Niigata University , the University of Tokyo, Osaka University and Tokyo Medical University, Japan have developed a new approach that could revolutionize the treatment, prevention, and possibly reversal of the damages caused by liver diseases.

3 May 2021

CGH and SUTD develop lightweight monitoring device to detect real-time bleeding from wounds

Changi General Hospital and the Singapore University of Technology and Design have developed the Blood WArning Technology with Continuous Haemoglobin (BWATCH) sensor, a lightweight monitoring device placed over a patient's bandage that detects real-time bleeding from wound sites following invasive medical procedures.

30 Apr 2021

Antiviral T cells safe, effective as off-the-shelf therapy for painful complication after stem cell transplants

A Phase II trial led by researchers at The University of Texas MD Anderson Cancer Center found that BK virus (BKV)-specific T cells from healthy donors were safe and effective as an off-the-shelf therapy for BKV-associated hemorrhagic cystitis (BKV-HC), a painful complication common after allogeneic stem cell transplants for patients with leukemia or lymphoma.

30 Apr 2021

Arresting tumor growth for a variety of cancers through T cell engineering

Through T cell engineering, researchers at Virginia Commonwealth University Massey Cancer Center show that it's possible to arrest tumor growth for a variety of cancers and squash the spread of cancer to other tissues.

30 Apr 2021

Correcting mutations in muscle stem cells using new gene-editing technology

A new gene-editing technique can be used to correct mutations in muscle stem cells, paving the way for the first potential cell therapy for genetic muscle disorders.

30 Apr 2021

FDA approves new drug for treatment of adults with chronic kidney disease

Today, the U.S. Food and Drug Administration approved Farxiga (dapagliflozin) oral tablets to reduce the risk of kidney function decline, kidney failure, cardiovascular death and hospitalization for heart failure in adults with chronic kidney disease who are at risk of disease progression.

30 Apr 2021

Study aims to refine delivery of tobacco treatment to people with HIV

Researchers at MUSC Hollings Cancer Center have received more than $2 million from the National Cancer Institute (NCI) to evaluate the impact of a proactive opt-out approach to smoking cessation on the health outcomes of people living with HIV.

30 Apr 2021

Applications of nanoparticles in combating COVID-19

Researchers review the various properties and use of nanoparticles in targeting SARS-CoV-2 and how they could be used to develop new therapeutics and diagnostics for SARS-CoV-2.

30 Apr 2021

Hepatitis C antivirals synergize with remdesivir to inhibit SARS-CoV-2 in vitro

A new study sheds light on the potential of drug combinations to stem viral transmission and treat patients with COVID-19. It also shows that four drugs used to treat hepatitis C synergize with remdesivir to make it up to ten times more effective at inhibiting SARS-CoV-2 in cell cultures.

30 Apr 2021

E-cigarette starter packs for smoking cessation to be given in hospitals

A new trial from the University of East Anglia will see smokers attending hospital emergency departments given e-cigarette starter packs to help them quit.

30 Apr 2021

The Christie NHS Foundation Trust first to offer treatment in cancer patients’ homes

One of Europe’s largest cancer centres, The Christie NHS Foundation Trust, has become the first in the country to provide a treatment called Phesgo for breast cancer patients in their own homes. Phesgo is a combination of Herceptin

30 Apr 2021

Evidence on effectiveness of digital mental health interventions for adolescents remains inconclusive

An increasing number of digital mental health interventions are designed for adolescents and young people with a range of mental health issues, but the evidence on their effectiveness is mixed, according to research by Columbia University Mailman School of Public Health and Spark Street Advisors.

30 Apr 2021

Therapy News and Research

Designing effective multidrug-resistant-TB treatments based on DNA sequencing

Chemotherapy drugs delivered via nanoparticles could improve bowel cancer survival rates

New gene therapy restores dystrophin protein in patients with Duchenne muscular dystrophy

Pulmonary endarterectomy improves outcomes in patients with segmental disease

New approach could revolutionize the treatment of liver diseases

CGH and SUTD develop lightweight monitoring device to detect real-time bleeding from wounds

Antiviral T cells safe, effective as off-the-shelf therapy for painful complication after stem cell transplants

Arresting tumor growth for a variety of cancers through T cell engineering

Correcting mutations in muscle stem cells using new gene-editing technology

FDA approves new drug for treatment of adults with chronic kidney disease

Study aims to refine delivery of tobacco treatment to people with HIV

Applications of nanoparticles in combating COVID-19

Hepatitis C antivirals synergize with remdesivir to inhibit SARS-CoV-2 in vitro

E-cigarette starter packs for smoking cessation to be given in hospitals

The Christie NHS Foundation Trust first to offer treatment in cancer patients’ homes

Evidence on effectiveness of digital mental health interventions for adolescents remains inconclusive

Study shows decline in prostate cancer diagnoses during the pandemic

Novel compound in avocados may offer a route to better leukemia treatment

Primary care practitioners overestimate disease risks leading to over-diagnosis and overtreatment

Study examines risk phenotypes of diabetes and their association with COVID-19 severity

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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