Respiratory News and Research

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FDA issues first emergency use authorization for second COVID-19 vaccine

Today, the U.S. Food and Drug Administration issued an emergency use authorization (EUA) for the second vaccine for the prevention of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

21 Dec 2020

Invirsa signs license agreement with AWRI to expand treatment platform for respiratory diseases

Invirsa, a Columbus-based pharmaceutical company, today announced execution of a license agreement with the Abigail Wexner Research Institute (AWRI) at Nationwide Children's Hospital as Invirsa seeks to broaden its treatment platform to address respiratory diseases.

20 Dec 2020

Study may help explain how COVID-19 increases stroke risk

A UCLA-led study may help explain how COVID-19 increases the risk for stroke. Scientists made the finding by running fluid spiked with a COVID-19-like protein through a 3D-printed model of the arteries of a patient who had suffered a stroke.

18 Dec 2020

Wildfire smoke's microbial content can cause infectious diseases

Wildfire smoke contains microbes, a fact that's often ignored, but one that may have important health repercussions.

18 Dec 2020

Research at Advanced Photon Source laid the groundwork for effective COVID-19 vaccines

There is light at the end of the COVID-19 pandemic tunnel. Several vaccines against the SARS-CoV-2 virus that causes COVID-19 are now in clinical trials, with one -- developed by Pfizer/BioNTech -- already having been approved for emergency use in the United States.

18 Dec 2020

Quantifying SARS-CoV-2 transmission in large urban areas

A team of international researchers used mobility information and socio-demographic data to build a model of SARS-CoV-2 transmission to understand where, when, and how many transmission events occurred in the first wave of the pandemic in the United States.

18 Dec 2020

Novel SARS-CoV-2 neutralizing antibody enters Phase 1/2a clinical study

Cologne University Hospital (UKK), University of Marburg (UMR), the German Center for Infection Research (DZIF) and Boehringer Ingelheim today announced the initiation of Phase 1/2a clinical investigation of BI 767551, a new SARS-CoV-2 neutralizing antibody.

18 Dec 2020

Higher COVID-19 mortality among certain groups in Colombia linked to structural inequalities

Researchers at the Ministry of Health and Social Protection in Bogotá, Colombia, provided evidence of socioeconomic inequalities in COVID-19 deaths in terms of age, sex, ethnicity, type of health insurance regime, and socioeconomic status.

18 Dec 2020

Very few COVID-19-positive children require hospitalization, finds case study

A team of researchers at the Divisions of Infectious Diseases, UPMC Children’s Hospital of Pittsburgh and the University of Pittsburgh, USA, sought to characterize the clinical presentation of children with COVID-19 in Western Pennsylvania.

18 Dec 2020

No more ICU beds at the main public hospital in the nation’s largest county as COVID surges

She lay behind a glass barrier, heavily sedated, kept alive by a machine that blew oxygen into her lungs through a tube taped to her mouth and lodged at the back of her throat. She had deteriorated rapidly since arriving a short time earlier.

18 Dec 2020

Remdesivir inhibits SARS-CoV-2 replication by preventing RdRp-mediated RNA translocation

A new study describes the in vitro mechanism by which remdesivir kinetically inhibits the replication of the virus that causes COVID-19, SARS-CoV-2.

18 Dec 2020

Can online health forums track the effect of COVID-19 on mental health?

A team of researchers at King's College London, UK, and other institutions used publicly accessible sources of real-world data, such as online health forums. They found that authors of COVID-19 related posts most frequently mentioned mental health symptom keywords during the first wave, followed by physical symptoms and intensive care keywords.

18 Dec 2020

Rapid no-frills detection of SARS-CoV-2 in saliva with LAMP-Cas13

A new paper that appeared as a preprint on the medRxiv* server in December 2020 describes a nucleic acid test validated on saliva samples.

18 Dec 2020

Rapid point-of-care lateral flow assay to assess the neutralizing activity of plasma against SARS-CoV-2

A new paper describes the development and validation of a rapid test to measure the neutralizing activity of serum against COVID-19 using a drop of blood.

18 Dec 2020

Study recommends blinded crossover and continued follow-ups to evaluate SARS-CoV-2 vaccine durability

A new multicenter study has shown that blinded crossover and continued follow-up of trial participants can help assess vaccine durability and potential delayed enhancement of disease.

18 Dec 2020

CN Bio and University of Melbourne announce partnership focused on respiratory therapies for recovering COVID-19 patients

CN Bio, a leading cell culture company, that has developed single and multi-organ microphysiological systems (MPS) to improve the accuracy and efficiency of drug discovery, today announced a collaboration with the University of Melbourne, focused on respiratory therapies for recovering COVID-19 patients.

18 Dec 2020

Experts to share the lessons learnt from COVID-19 first wave

The Physiological Society and the Intensive Care Society have come together to host an exciting three-day virtual conference this week, which will review the challenges of understanding the pathophysiological changes occurring throughout the body following COVID-19 infection.

18 Dec 2020

Respiratory News and Research

FDA issues first emergency use authorization for second COVID-19 vaccine

Invirsa signs license agreement with AWRI to expand treatment platform for respiratory diseases

Study may help explain how COVID-19 increases stroke risk

Wildfire smoke's microbial content can cause infectious diseases

Research at Advanced Photon Source laid the groundwork for effective COVID-19 vaccines

Quantifying SARS-CoV-2 transmission in large urban areas

Novel SARS-CoV-2 neutralizing antibody enters Phase 1/2a clinical study

Higher COVID-19 mortality among certain groups in Colombia linked to structural inequalities

Very few COVID-19-positive children require hospitalization, finds case study

No more ICU beds at the main public hospital in the nation’s largest county as COVID surges

Remdesivir inhibits SARS-CoV-2 replication by preventing RdRp-mediated RNA translocation

Can online health forums track the effect of COVID-19 on mental health?

Rapid no-frills detection of SARS-CoV-2 in saliva with LAMP-Cas13

Rapid point-of-care lateral flow assay to assess the neutralizing activity of plasma against SARS-CoV-2

Study recommends blinded crossover and continued follow-ups to evaluate SARS-CoV-2 vaccine durability

CN Bio and University of Melbourne announce partnership focused on respiratory therapies for recovering COVID-19 patients

Experts to share the lessons learnt from COVID-19 first wave

Project explores how carers recognize and manage health deterioration in people with learning disabilities, autism

Research shows that people affected with COVID-19 suffer from cognitive effects

A protein may be responsible for triggering lung scarring in scleroderma patients

Industry Focus eBook - Neurology/Neuroscience - 2nd edition eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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