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B-cell responses to COVID mRNA vaccine are enhanced by a 16-week interval between doses

Researchers assess the impact of extending the interval between primary and booster COVID-19 vaccine doses.

9 Aug 2022

The eyes of mutant zebrafish help understand the role of a protein in preventing cell death

Around 15 years ago, a group of researchers discovered mutant zebrafish. The eyes of these zebrafish did not develop correctly, resulting in them being significantly smaller than the eyes of wild zebrafish.

9 Aug 2022

Researchers create the most bio-realistic and complex computer models of brain cells

Cedars-Sinai investigators have created the most bio-realistic and complex computer models of individual brain cells - in unparalleled quantity.

9 Aug 2022

Aberrant levels of three microRNAs may impair healing in venous ulcers, study shows

The study, which includes the first resource detailing the role of microRNAs in the wound-repair process, shows that aberrant levels of a trio of microRNAs may impair healing in venous ulcers.

9 Aug 2022

Researchers develop a potential way to tackle one of the underlying causes of asthma

A possible way to tackle one of the underlying causes of asthma has been developed by researchers from Aston University and Imperial College London.

9 Aug 2022

Study uncovers how common genetic mutations cause renal cancer

The understanding of the link between common genetic mutations and certain cancers is increasing.

9 Aug 2022

Double mRNA COVID-19 vaccination found to increase SARS-CoV-2 variant recognition

Researchers evaluated the impact of double BNT162b2 messenger ribonucleic acid (mRNA) vaccination in recognition of SARS-CoV-2 variants of concern.

9 Aug 2022

Scientists explore ex utero generation of post-gastrulation synthetic embryos

Researchers showed that post-gastrulation synthetic embryos (sEmbryos) could be synthesized outside the uterus using mouse naive embryonic stem cells (ESCs).

9 Aug 2022

A genome-wide catalog of rare copy-number variant associations for 54 disease phenotypes

A recent study published in Cell illustrated a human genome map with dosage sensitivity across disorders.

9 Aug 2022

The neutralizing activity of a panel of 482 human monoclonal antibodies against Omicron BA.4 and BA.5

Researchers demonstrated differential utilization of the B cell germlines and SARS-CoV-2 spike protein epitopes by cross-neutralizing antibodies in infected, vaccinated and individuals with hybrid immunity.

9 Aug 2022

How does the interval between the 1st and 2nd BNT162b2 doses impact the neutralization breadth and potency against variants of concern?

Scientists explored the influence of SARS-CoV-2 extended gap vaccination on the variants of concern neutralization.

9 Aug 2022

Evaluating vaccine effectiveness against Omicron BA.5 and BA.2 in Portugal

Researchers estimated the vaccine effectiveness (VE) of the primary and booster doses of COVID-19 vaccines against reinfection by Omicron BA.5 and BA.2 lineages and severe post-infection outcomes.

9 Aug 2022

Study suggests BA.5 evolved to induce enhanced inflammation when compared to prior Omicron subvariants

Researchers evaluated the comparative pathogenicity of SARS-CoV-2 Omicron sub-variants BA.1, BA.2, and BA.5, in vitro and in vivo.

9 Aug 2022

Novel AI tools accurately predict the role of DNA’s regulatory elements

Newly developed artificial intelligence (AI) programs accurately predicted the role of DNA's regulatory elements and three-dimensional (3D) structure based solely on its raw sequence, according to two recent studies in Nature Genetics.

9 Aug 2022

Study reveals key similarities between the nervous system of two early-diverging animal lineages

Neurons, the specialized cells of the nervous system, are possibly the most complicated cell type ever to have evolved. In humans, these cells are capable of processing and transmitting vast sums of information. But how such complicated cells first came about remains a long-standing debate.

9 Aug 2022

Powerful injectable gel provides hope for preventing glioblastoma relapse

Like the hardiest weed, glioblastoma almost always springs back - usually within months after a patient's initial brain tumor is surgically removed.

8 Aug 2022

Disruption of the circadian clocks plays a key role in weight gain

Disruption of the circadian clocks that keep the body and its cells entrained to the 24-hour day-night cycle plays a critical role in weight gain, according to a pair of studies by Weill Cornell Medicine investigators.

8 Aug 2022

Proof-of-concept model uses AI to combine multiple types of data to predict cancer outcomes

While it's long been understood that predicting outcomes in patients with cancer requires considering many factors, such as patient history, genes and disease pathology, clinicians struggle with integrating this information to make decisions about patient care.

8 Aug 2022

Higher doses of CAR-T therapy achieve better survival rates for young patients with hard-to-treat B-ALL

Young people who received doses of tisagenlecleucel, a chimeric antigen receptor T cell (CAR-T) therapy, at the higher end of the FDA-approved dosing range had significantly better survival rates at one year compared with those who received lower doses within this range, according to research published today in Blood Advances.

8 Aug 2022

Yale researchers discover molecular mechanism behind growth of the nervous system

Our nervous system is composed of billions of neurons that speak to each other through their axons and dendrites.

8 Aug 2022

B Cell News and Research

B-cell responses to COVID mRNA vaccine are enhanced by a 16-week interval between doses

The eyes of mutant zebrafish help understand the role of a protein in preventing cell death

Researchers create the most bio-realistic and complex computer models of brain cells

Aberrant levels of three microRNAs may impair healing in venous ulcers, study shows

Researchers develop a potential way to tackle one of the underlying causes of asthma

Study uncovers how common genetic mutations cause renal cancer

Double mRNA COVID-19 vaccination found to increase SARS-CoV-2 variant recognition

Scientists explore ex utero generation of post-gastrulation synthetic embryos

A genome-wide catalog of rare copy-number variant associations for 54 disease phenotypes

The neutralizing activity of a panel of 482 human monoclonal antibodies against Omicron BA.4 and BA.5

How does the interval between the 1st and 2nd BNT162b2 doses impact the neutralization breadth and potency against variants of concern?

Evaluating vaccine effectiveness against Omicron BA.5 and BA.2 in Portugal

Study suggests BA.5 evolved to induce enhanced inflammation when compared to prior Omicron subvariants

Novel AI tools accurately predict the role of DNA’s regulatory elements

Study reveals key similarities between the nervous system of two early-diverging animal lineages

Powerful injectable gel provides hope for preventing glioblastoma relapse

Disruption of the circadian clocks plays a key role in weight gain

Proof-of-concept model uses AI to combine multiple types of data to predict cancer outcomes

Higher doses of CAR-T therapy achieve better survival rates for young patients with hard-to-treat B-ALL

Yale researchers discover molecular mechanism behind growth of the nervous system

Industry focus eBook - Cell and gene therapy (2nd edition) eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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