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CarThera receives €5.7 million grant for DOME project from France’s Investments for the Future Program

CarThera, which designs and develops innovative medical devices to treat brain disorders, today announces it has received a grant of €5.7 million ($6.4m) for its DOME project.

13 Oct 2016

Clinical study to determine safety, efficacy of allogeneic CDCs for patients with myocardial infarction

A multi-center team of researchers are planning a clinical trial using cardiosphere-derived cells (CDCs) (a heterogeneous cluster of proliferating cardiac cells that include mesenchymal stem cells) to regenerate the tissue and improve function of the heart in patients who have suffered heart attacks (myocardial infarction, MI).

13 Oct 2016

RT-IMRI guidance improves safety, efficacy of stem cell treatment for Parkinson's disease

In a study using Real-time intraoperative magnetic resonance imaging (RT-IMRI) to guide the transplantation of induced pluripotent stem cell (iPSC)-derived neurons into the brains of non-human primates modeled with Parkinson's disease, researchers found that RT-IMRI guidance not only allows for better visualization and monitoring of the procedure, but also helps cell survival.

13 Oct 2016

Study to investigate clinical impact of new treatment for HFrEF patients

The academic partners in the VerICiguaT GlObal Study in Subjects with Heart Failure with Reduced EjectIon FrAction are pleased to announce that patient enrollment has begun.

12 Oct 2016

Novel biomarkers enhance power to predict therapeutic efficacy in LN prognostic models

Results of preclinical studies by investigators at the Medical University of South Carolina reported in the August 2016 issue of Arthritis & Rheumatology demonstrate for the first time that including novel biomarkers in lupus nephritis (LN) prognostic models significantly increases their power to predict therapeutic efficacy.

12 Oct 2016

An inclusive approach to COPD research: an interview with Dr David Leather

About eight years ago the WHO put out a call saying that we needed data that better represented real world patients. Our ambition was to create evidence earlier in the life cycle of medicine that better represented the population that would...

11 Oct 2016

Study to examine efficacy of orally administered medication in treating stuttering

Stuttering, an interruption in the flow of speech, affects about three million Americans. It begins most often in childhood, affecting four men for every woman. A precise cause of this complex communicative disorder is not known.

8 Oct 2016

PARP inhibitor prolongs progression-free survival in patients with recurrent ovarian cancer

The PARP inhibitor niraparib significantly improves the outcome of platinum-sensitive recurrent ovarian cancer, according to full data from the ENGOT-OV16/NOVA trial presented for the first time at the ESMO 2016 Congress in Copenhagen and published in the New England Journal of Medicine.

8 Oct 2016

Immunotherapy redefines treatment approach for metastatic bladder cancer patients

Immunotherapy has shown promising results in first and second line treatment of metastatic bladder cancer in two phase II trials presented at the ESMO 2016 Congress in Copenhagen.

8 Oct 2016

New study of Phase II Alzheimer's drug pipeline reveals more ways to combat disease

A new analysis of the Phase II Alzheimer's drug pipeline, conducted by ResearchersAgainstAlzheimer's, revealed 57 new Alzheimer's drugs. According to the analysis, nearly twice as many mechanisms of action are being tested in Phase II than in Phase III clinical trials.

7 Oct 2016

RTI extends research support to improve treatment for pelvic floor disorders in women

RTI International will continue supporting research efforts to improve clinical care for women with pelvic floor disorders as part of the Pelvic Floor Disorders Network.

6 Oct 2016

Treatment using PARP inhibitor shrinks tumors in breast cancer patients with BRCA mutations

All 13 newly diagnosed breast cancer patients with BRCA mutations had their tumors shrink significantly when treated with a PARP inhibitor ahead of frontline presurgical chemotherapy in a pilot study at The University of Texas MD Anderson Cancer Center.

5 Oct 2016

JAK inhibitors show promise in restoring hair growth in patients with alopecia areata

Seventy-five percent of patients with moderate to severe alopecia areata--an autoimmune disease that causes patchy, and less frequently, total hair loss--had significant hair regrowth after treatment with ruxolitinib, reported researchers from Columbia University Medical Center. By the end of their treatment, average hair regrowth was 92 percent.

5 Oct 2016

Study evaluates outcomes of hypothermia treatment among patients with in-hospital cardiac arrest

In a study appearing in the October 4 issue of JAMA, Paul S. Chan, M.D., of Saint Luke's Mid America Heart Institute, Kansas City, and colleagues evaluated the association of hypothermia treatment with survival to hospital discharge and with favorable neurological survival at hospital discharge among patients with in-hospital cardiac arrest.

4 Oct 2016

Study shows how common intestinal microbe protects the gut from attack by harmful bacteria

Antibiotics save millions of lives. But their tendency to kill helpful and harmful bacteria alike, coupled with the growing problem of antibiotic resistance, means that they are not without their downside.

4 Oct 2016

$New review shows both types of diabetes increase risk of fragility fractures$

Efficacy News and Research

CarThera receives €5.7 million grant for DOME project from France’s Investments for the Future Program

Clinical study to determine safety, efficacy of allogeneic CDCs for patients with myocardial infarction

RT-IMRI guidance improves safety, efficacy of stem cell treatment for Parkinson's disease

Study to investigate clinical impact of new treatment for HFrEF patients

Novel biomarkers enhance power to predict therapeutic efficacy in LN prognostic models

An inclusive approach to COPD research: an interview with Dr David Leather

Study to examine efficacy of orally administered medication in treating stuttering

PARP inhibitor prolongs progression-free survival in patients with recurrent ovarian cancer

Immunotherapy redefines treatment approach for metastatic bladder cancer patients

New study of Phase II Alzheimer's drug pipeline reveals more ways to combat disease

RTI extends research support to improve treatment for pelvic floor disorders in women

Treatment using PARP inhibitor shrinks tumors in breast cancer patients with BRCA mutations

JAK inhibitors show promise in restoring hair growth in patients with alopecia areata

Study evaluates outcomes of hypothermia treatment among patients with in-hospital cardiac arrest

Study shows how common intestinal microbe protects the gut from attack by harmful bacteria

New review shows both types of diabetes increase risk of fragility fractures

IMRT linked to reduced xerostomia and feeding tube dependency in oropharyngeal cancer patients

Study highlights impact of cognitive functions on oral cancer treatment

Trial evaluates efficacy of chiropractic spinal manipulative therapy for treating migraines

Study examines fecal microbiota transplantation as treatment option for recurrent C. difficile infections

Industry Focus eBook - Neurology/Neuroscience - 2nd edition eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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