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Intratumoral morphological diversity of breast cancer not related to chromosome aberrations

Intratumor morphological heterogeneity (diversity) of breast cancer is not related to chromosome aberrations. This conclusion was made based on the study of one case with aggressive variant of breast cancer - invasive micropapillary carcinoma by researchers from Tomsk State University, Tomsk Cancer Research Institute, and Institute of Medical Genetics.

30 Sep 2015

Study explores how the human brain contributes to success

Discoveries about how the human brain contributes to our success - both as a species and as individuals - are among the first fruit of projects funded under the National Institutes of Health BRAIN Initiative program as well as the Human Connectome Project.

30 Sep 2015

Stroke patients with spatial neglect more likely to fall and have longer stays in hospital

Using the Kessler Foundation Neglect Assessment Process (KF-NAP), Kessler researchers found a high rate of spatial neglect among inpatients with stroke. Affected patients had a higher risk for falls, longer lengths of stay and lesser likelihood of returning home after discharge.

30 Sep 2015

New software programs may help speed up drug discovery process for diabetes and other diseases

Proteins sometimes run amuck. All the good stuff (the useful genetic and biological material) they contain can get distorted. Mutations in specific amino acids can cause long strands of proteins to curl in on themselves (like a ball of wool a cat has played with) and refuse to break apart.

30 Sep 2015

Discrimination leads to dangerous health consequences among transgender Americans

Despite a surge in public attention toward the transgender population, transgender adults continue to face both major and daily discrimination that often directly leads to dangerous health consequences.

30 Sep 2015

Age, race and family history are the biggest risk factors for prostate cancer, new research suggests

New research suggests that age, race and family history are the biggest risk factors for a man to develop prostate cancer, although high blood pressure, high cholesterol, vitamin D deficiency, inflammation of prostate, and vasectomy also add to the risk. In contrast, obesity, alcohol abuse, and smoking show a negative association with the disease.

30 Sep 2015

Risks of developing type 2 diabetes for South Asians begin immediately at birth

New research suggests that the risks of developing type 2 diabetes for South Asians - a group long known to suffer from substantially higher rates of both diabetes and heart disease—begins immediately at birth.

30 Sep 2015

New research identifies genetic variants, causal links associated with polycystic ovary syndrome

In the largest genome wide association study (GWAS) into polycystic ovary syndrome (PCOS) to date, new research conducted by scientists at the University of Cambridge and ten other institutions, including 23andMe, has identified genetic variants and causal links associated with PCOS, some of which might be relevant to informing positive lifestyle and treatment choices for women.

30 Sep 2015

Serologic status and autoimmune cerebellar ataxia type predict treatment response

Patients with autoimmune cerebellar ataxia have better treatment responses and outcomes if they have the nonparaneoplastic form of the condition and are seropositive for neural plasma membrane protein or glutamic acid decarboxylase 65 antibodies, suggests research.

29 Sep 2015

GIOTRIF shows superior survival compared to Tarceva for patients previously treated with advanced squamous cell lung carcinoma

Boehringer Ingelheim today announced at the European Cancer Congress (ECC) in Vienna, Austria, new data from the Phase III LUX-Lung 8 trial which further highlights the benefits of afatinib compared to erlotinib for the treatment of patients with previously treated advanced SCC of the lung

29 Sep 2015

New report implicates five genetic regions that play major roles in CF disease severity

If you have two faulty copies of the CFTR gene, you will have cystic fibrosis. But the severity of your disease will depend on environmental factors and many other genes. Locating these genes and altering their function could lead to new therapies.

29 Sep 2015

Clinical trial initiated to determine feasibility, safety of focused ultrasound to treat depression

The first patient with depression has been treated with focused ultrasound. This procedure marks the beginning of a pilot clinical trial to determine the feasibility and safety of MR-guided focused ultrasound to non-invasively destroy a small volume of tissue deep in the brain - the anterior limb of the internal capsule - a well-established target for treating severe depression.

29 Sep 2015

Current fetal growth standards do not consider racial and ethnic differences

Current standards for ultrasound evaluation of fetal growth may lead to misclassification of up to 15 percent of fetuses of minority mothers as being too small, according to a study by researchers at the National Institutes of Health (NIH) and other institutions.

29 Sep 2015

Vaginal birth preferable in next childbirth for women who have given birth by caesarean section

In many countries, caesarean section is routinely used if the woman previously gave birth by caesarean section. Doctors and midwives in countries with a high rate of vaginal births after caesarean sections have for the first time been asked in a study to give their views on how to increase the percentage of vaginal births.

29 Sep 2015

Academies and DFG point out limitations and risks of new genome editing techniques

More efficient bacteria and yeasts for use in fuel and drug production, new strategies to combat antibiotic-resistant germs, and innovative plant breeding methods - new molecular biology techniques that permit targeted genetic modification are giving rise to many promising new opportunities in research and application.

29 Sep 2015

Study: Bright light therapy reduces depression and agitation in dementia sufferers

Dementia is most often associated with memory loss, but seniors who suffer from the condition also experience depression and agitation. These symptoms are often treated with medication.

29 Sep 2015

Updated review finds continued lack of evidence on best fat grafting procedures

Fat grafting—taking fat from one area of the body and transferring it elsewhere—has become a widely used plastic surgery technique. But what's the best method of processing cells for fat grafting procedures?

29 Sep 2015

New drug may prevent malaria in pregnant women

Researchers at LSTM, working with colleagues of the Centres for Disease Control and Prevention (CDC) in Kenya and USA, and from the Kenya Medical Research Institution have found that a new drug may be more effective at preventing malaria in pregnant woman, especially where there is resistance to the current treatments.

29 Sep 2015

Study examines how active senior travellers use tourism-related information technology

Are you an Adventurous Experimenter, a Meticulous Researcher or a Fumbling Observer? These are the three groups active senior travellers can be divided into on the basis of how they use tourism-related information and communication technology, according to a recent University of Eastern Finland and Jyväskylä University of Applied Sciences study.

29 Sep 2015

Disruption of blood-CSF barrier may negatively affect progression of Alzheimer's disease

More and more data from preclinical and clinical studies strengthen the hypothesis that immune system-mediated actions contribute to and drive pathogenesis in Alzheimer's disease. The team of Roosmarijn Vandenbroucke in the Claude Libert Group (VIB/UGent) combined their knowledge and expertise related to inflammation with the expertise in Alzheimer's disease present in the Bart De Strooper Group (VIB/KU Leuven).

29 Sep 2015

Research News and Research

Intratumoral morphological diversity of breast cancer not related to chromosome aberrations

Study explores how the human brain contributes to success

Stroke patients with spatial neglect more likely to fall and have longer stays in hospital

New software programs may help speed up drug discovery process for diabetes and other diseases

Discrimination leads to dangerous health consequences among transgender Americans

Age, race and family history are the biggest risk factors for prostate cancer, new research suggests

Risks of developing type 2 diabetes for South Asians begin immediately at birth

New research identifies genetic variants, causal links associated with polycystic ovary syndrome

Serologic status and autoimmune cerebellar ataxia type predict treatment response

GIOTRIF shows superior survival compared to Tarceva for patients previously treated with advanced squamous cell lung carcinoma

New report implicates five genetic regions that play major roles in CF disease severity

Clinical trial initiated to determine feasibility, safety of focused ultrasound to treat depression

Current fetal growth standards do not consider racial and ethnic differences

Vaginal birth preferable in next childbirth for women who have given birth by caesarean section

Academies and DFG point out limitations and risks of new genome editing techniques

Study: Bright light therapy reduces depression and agitation in dementia sufferers

Updated review finds continued lack of evidence on best fat grafting procedures

New drug may prevent malaria in pregnant women

Study examines how active senior travellers use tourism-related information technology

Disruption of blood-CSF barrier may negatively affect progression of Alzheimer's disease

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