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Research on patients' immune system may lead to new diagnostic tool for HIV treatment

Mayo Clinic researchers have shown why, in a minority of HIV patients, immune function improves despite a lack of response to standard anti-retroviral treatment. In these cases, researchers say, the virus has lost its ability to kill immune cells. The findings appear in the online journal PLoS Pathogens.

1 Dec 2010

Study finds boosting glucose levels can reduce aggressive behavior

A spoonful of sugar may be enough to cool a hot temper, at least for a short time, according to new research. A study found that people who drank a glass of lemonade sweetened with sugar acted less aggressively toward a stranger a few minutes later than did people who consumed lemonade with a sugar substitute.

1 Dec 2010

New tool to trace metabolism of carotenoids in human body

The University of Illinois scientists who linked eating tomatoes with a reduced risk of prostate cancer have developed a tool that will help them trace the metabolism of tomato carotenoids in the human body. And they've secured funding from the National Institutes of Health to do it.

30 Nov 2010

Ageing reversed in mice: Study

A scientific team at Harvard-affiliated medical centers genetically manipulated mice to age faster. Then they used gene therapy to lengthen telomeres. Telomeres are compounds found at the ends of strands of DNA that are related to age. This lengthening of telomeres reversed age-related problems such as decreased brain function and infertility.

29 Nov 2010

Amarin reports top-line results from AMR101 Phase 3 trial for treatment of high triglycerides

Amarin Corporation plc, a clinical-stage biopharmaceutical company with a focus on cardiovascular disease, today reported positive, statistically significant top-line results from the MARINE study, its first Phase 3 clinical trial of lead drug candidate AMR101.

29 Nov 2010

New strategy to prevent memory deficits in mouse model with AD

Scientists at the Gladstone Institute of Neurological Disease (GIND) in San Francisco have discovered a new strategy to prevent memory deficits in a mouse model of Alzheimer's disease (AD).

28 Nov 2010

GFS solution to Cholera

GFS BioProtect™ Effluent Remediator kills Vibrio cholerae O: 1, serotype Ogawa to Log 3 immediately, and the kill rate for this and several other pathogens continues to improve over time. The product breaks down B Class biomass (latrine and septic tank waste) into A class biomass suitable for reuse.

28 Nov 2010

JAK3 pathway highlighted as leukemia target

An intriguing study published in Expert Review of Anticancer Therapy has revealed that the signaling protein JAK3 represents a viable target in the treatment of a broad range of B-lineage cancers, including acute lymphoblastic leukemia (ALL).

28 Nov 2010

Most 'worried well' groups at risk of liver disease

Growing groups of the so-called "worried well" are putting their lives at risk by shunning visits to their GP over alcoholic health related matters, according to new evidence.

25 Nov 2010

Immunity-enhancing probiotics may be the best line of defense for good health

Good bacteria, bad bacteria, billions of bacteria—sounds downright germy. But the truth is that research in gut health is germinating more insight into the role bacteria, also known as "probiotics," play in our overall health and wellness.

25 Nov 2010

E. coli host bacterium produces antibiotic erythromycin A

Researchers at Tufts University School of Engineering have reported the first successful production of the antibiotic erythromycin A, and two variations, using E. coli as the production host.

24 Nov 2010

A new treatment landscape for triple-negative breast cancer

A concerted R&D effort directed at triple-negative breast cancer patients promises new treatment options in the near future, according to latest research from independent market analyst, Datamonitor.

24 Nov 2010

On Thanksgiving Day never mind conflict with the in-laws; it's cake vs. cranberry, pie vs. wine

If you're lucky, it will all be kisses and hugs around the Thanksgiving dinner table, with friends and family near and dear gathered about, and puppies gathered around your feet waiting for table scraps.

24 Nov 2010

Plant-derived bioscavenger protects against pesticide and nerve agent organophosphate poisoning

The brain is forever chattering to itself, via electrical impulses sent along its hard-wired neuronal "Ethernet." These e-messages are translated into chemical transmissions, allowing communication across the narrow cleft separating one neuron from another or between neurons and their target cells. Of the many kinds of molecules involved in this lively chemical symposium, acetylcholine is among the most critical, performing a host of functions in the central and peripheral nervous system.

24 Nov 2010

Blocking miR-375 microRNA in ERalha-positive breast cancer cells slows down cancer cell growth

Two thirds of breast cancers are ERalpha-positive, i.e., many estrogen receptors of the ERalpha- type are found in their cells. "These molecules can interact with the estrogen hormone and, thus, even lead to cancer," explains Dr. Joerg Hoheisel; molecular biologist at DKFZ. "The connection between the levels of the estrogen receptor alpha and the occurrence of breast cancer has been known for some time now.

24 Nov 2010

Verenium enters agreement with Desmet Ballestra for Purifine enzymatic degumming process

Verenium Corporation, a pioneer in the development and commercialization of high-performance enzymes solutions, today announced an agreement with Desmet Ballestra Group s.a., a leading global solutions provider in the field of engineering and delivery of installations and equipment for the edible oil and fats and biodiesel industries, to jointly market the Purifine enzymatic degumming process, which combines Verenium's Purifine PLC enzyme and Desmet Ballestra's engineering services and equipment.

23 Nov 2010

Vertex submits NDA for telaprevir for treating hepatitis C

Vertex Pharmaceuticals Incorporated announced that it has completed the submission of a New Drug Application (NDA) to the U.S. Food and Drug Administration (FDA) seeking approval for telaprevir, Vertex's investigational treatment for people with hepatitis C.

23 Nov 2010

Rate, direction of axon growth in spinal cord can be controlled, study shows

Both the rate and direction of axon growth in the spinal cord can be controlled, according to new research by USC College's Samantha Butler and her collaborators.

23 Nov 2010

Transparent develops new medium for Cell-able array kit to maintain metabolite activity

Transparent Inc. announced that it has developed a more advanced medium for Cell-able, a human hepatocyte array kit that has the potential to reduce drug development costs and time-to-market for pharmaceutical companies. Transparent first introduced Cell-able in the United States a year ago.

22 Nov 2010

Interim results from H.P. Acthar Gel study in patients with advanced diabetic nephropathy

On November 20 at the American Society of Nephrology 43rd Annual Meeting, interim results presented from an ongoing, randomized prospective study conducted independently by James A. Tumlin, MD, at the University of Tennessee College of Medicine Chattanooga indicated that 9 of 15 patients (60%) with advanced diabetic nephropathy who are currently enrolled in the study and have completed or are still undergoing a six month course of treatment with H.P. Acthar ® Gel have exhibited a clinically significant decrease in proteinuria and achieved stabilized renal function.

22 Nov 2010

Enzyme News and Research

Research on patients' immune system may lead to new diagnostic tool for HIV treatment

Study finds boosting glucose levels can reduce aggressive behavior

New tool to trace metabolism of carotenoids in human body

Ageing reversed in mice: Study

Amarin reports top-line results from AMR101 Phase 3 trial for treatment of high triglycerides

New strategy to prevent memory deficits in mouse model with AD

GFS solution to Cholera

JAK3 pathway highlighted as leukemia target

Most 'worried well' groups at risk of liver disease

Immunity-enhancing probiotics may be the best line of defense for good health

E. coli host bacterium produces antibiotic erythromycin A

A new treatment landscape for triple-negative breast cancer

On Thanksgiving Day never mind conflict with the in-laws; it's cake vs. cranberry, pie vs. wine

Plant-derived bioscavenger protects against pesticide and nerve agent organophosphate poisoning

Blocking miR-375 microRNA in ERalha-positive breast cancer cells slows down cancer cell growth

Verenium enters agreement with Desmet Ballestra for Purifine enzymatic degumming process

Vertex submits NDA for telaprevir for treating hepatitis C

Rate, direction of axon growth in spinal cord can be controlled, study shows

Transparent develops new medium for Cell-able array kit to maintain metabolite activity

Interim results from H.P. Acthar Gel study in patients with advanced diabetic nephropathy

Measuring Drug-Target Residence Times with Biochemical Assays eBook

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