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New biomarker test helps detect autoimmune-induced neuropsychiatric disorders

A research team from the University of Oklahoma Health Sciences Center, led by Madeleine Cunningham, Ph.D., in conjunction with the National Institute of Mental Health, has developed the first-of-its-kind biomarker test to help detect autoimmune-induced neuropsychiatric disorders.

9 Sep 2016

Triptolide molecule can turn into 'cruise missile' against cancer

More than 20 years ago, a billboard in China piqued the interest of a chemical biologist. It endorsed an extract from the plant known as the “thunder god vine” as an immunosuppressant.

9 Sep 2016

Right dose of CAR T cells and lymphodepletion can achieve good response rates for NHL patients

In a paper published today in Science Translational Medicine, researchers from Fred Hutchinson Cancer Research Center shared data from an early-phase study of patients with advanced non-Hodgkin lymphoma (NHL) who received JCAR014, a Chimeric Antigen Receptor (CAR) T cell treatment, and chemotherapy.

9 Sep 2016

Steroids for treating infertility in women may have harmful effects on pregnancy and child

Researchers at the University of Adelaide are urging doctors and patients to refrain from using a specific steroid treatment to treat infertility in women unless clinically indicated, because of its links to miscarriage, preterm birth and birth defects.

9 Sep 2016

Researchers discover how immune cells transition from silent to merciless killing machines

Neutrophils are the superheroes of the body's immune system. Normally mild-mannered, they travel through the bloodstream until they reach an emergency situation, such as a cut or infection, where they switch into battle-mode to engulf and destroy foreign invaders.

9 Sep 2016

UC researchers offer more insights into how lack of gut bacteria influences fat absorption

A study led by University of Cincinnati lipid metabolism researchers lends additional insight into how bacteria in the gut, or lack thereof, influences intestinal mast cells (MMC) activation and perhaps fat absorption.

9 Sep 2016

Novel Trojan Horse antibody strategy may target Ebola's Achilles' heel

In research published online today in Science, a team of scientists describe a new therapeutic strategy to target a hidden Achilles' heel shared by all known types of Ebola virus.

8 Sep 2016

Trial of high-dose flu vaccine aims to better protect heart failure patients

A network of researchers in the United States and Canada will try to spare thousands of patients the dangers of heart attacks and hospitalizations over the next five years in a trial of a high-dose flu vaccine.

8 Sep 2016

New immunotherapy treatment may offer hope for many pancreatic cancer patients

A new immunotherapy treatment has shown dramatic results in treating advanced pancreatic cancer, a deadly cancer that has seen little progress in treatment over the last 20 years.

8 Sep 2016

Early life exposure to antibiotics found to increase allergy risk later in life

An analysis of almost 400,000 people has shown that exposure to antibiotics in early life is linked to an increased risk of developing allergies later in life.

8 Sep 2016

Stealth insulin-producing pig cells may offer solution for treating Type 1 diabetes in humans

University of Alabama at Birmingham researchers are exploring ways to wrap pig tissue with a protective coating to ultimately fight diabetes in humans. The nano-thin bilayers of protective material are meant to deter or prevent immune rejection.

8 Sep 2016

Patients with noninfectious uveitis can get effective treatment from corticosteroid alternative

Patients suffering from noninfectious uveitis, a group of diseases that causes eye inflammation, can get effective treatment from a corticosteroid alternative that has previously been approved for treatment of arthritis and Crohn's disease, according to a study led by a Duke Health researcher.

8 Sep 2016

New blood test helps identify bacterial infection in infants with fever

A blood test used to measure patterns of ribonucleic acid (RNA) expression can help determine if fever in infants under 2 months old is caused by bacterial or viral infection, according to a preliminary study recently published in the Journal of the American Medical Association.

8 Sep 2016

Intestinal microbiota may play role in food allergies

Countless microorganisms live in the intestinal tract. Researchers at the Technical University of Munich have been able to demonstrate that intestinal bacteria also play a role in determining the strength of anaphylactic reactions to food allergens.

7 Sep 2016

Researchers find genomic material from Zika virus in tears

Researchers have found that Zika virus can live in eyes and have identified genetic material from the virus in tears, according to a study from Washington University School of Medicine in St. Louis.

7 Sep 2016

Children exposed to e-cigarette ads underestimate occasional tobacco smoking risks

Estimates suggest that among children who try smoking, between one third and one half are likely to become regular smokers within two to three years.

7 Sep 2016

Researchers discover second line of defense in macaques co-infected with Mtb and SIV

Tulane University researchers found some monkeys whose immune systems are depleted by the simian strain of HIV have a second line of defense against tuberculosis.

7 Sep 2016

Fungal communities in chronic wounds can be linked to poor outcomes and slow healing

Researchers in Pennsylvania and Iowa have discovered that fungal communities found in chronic wounds can form mixed bacterial-fungal biofilms and can be associated with poor outcomes and longer healing times.

6 Sep 2016

New drug holds potential for treating advanced mastocytosis

Most people have never heard of mastocytosis. It's a rare, sometimes deadly, immune disorder. Now new research may help those with advanced mastocytosis and possibly many more people, too.

6 Sep 2016

Caltech scientists uncover three-dimensional structure of disease-fighting protein

The polymeric immunoglobulin receptor, or pIgR, is a multitasking protein produced in the lining of mucosal surfaces, such as the intestines. It plays a pivotal role in the body's immune functions by sequestering bacteria and by assisting antibodies—large proteins that can identify and neutralize specific bacteria and viruses.

6 Sep 2016

Immune System News and Research

New biomarker test helps detect autoimmune-induced neuropsychiatric disorders

Triptolide molecule can turn into 'cruise missile' against cancer

Right dose of CAR T cells and lymphodepletion can achieve good response rates for NHL patients

Steroids for treating infertility in women may have harmful effects on pregnancy and child

Researchers discover how immune cells transition from silent to merciless killing machines

UC researchers offer more insights into how lack of gut bacteria influences fat absorption

Novel Trojan Horse antibody strategy may target Ebola's Achilles' heel

Trial of high-dose flu vaccine aims to better protect heart failure patients

New immunotherapy treatment may offer hope for many pancreatic cancer patients

Early life exposure to antibiotics found to increase allergy risk later in life

Stealth insulin-producing pig cells may offer solution for treating Type 1 diabetes in humans

Patients with noninfectious uveitis can get effective treatment from corticosteroid alternative

New blood test helps identify bacterial infection in infants with fever

Intestinal microbiota may play role in food allergies

Researchers find genomic material from Zika virus in tears

Children exposed to e-cigarette ads underestimate occasional tobacco smoking risks

Researchers discover second line of defense in macaques co-infected with Mtb and SIV

Fungal communities in chronic wounds can be linked to poor outcomes and slow healing

New drug holds potential for treating advanced mastocytosis

Caltech scientists uncover three-dimensional structure of disease-fighting protein

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