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Researchers receive $2.1 million NIH grant to study causes of congenital heart defects

Congenital heart defects are the most common type of birth defect, affecting nearly 1% of births in the United States each year, according to the Centers for Disease Control. Doctors have been unable to lower that number due to a lack of knowledge about their source.

5 Jan 2021

Inhibition of blood clotting factor reduces the formation of brain metastases in mice

Brain metastases can only develop if cancer cells first exit the fine blood vessels and enter into the brain tissue.

5 Jan 2021

Repeated ketamine infusions may be a promising treatment for PTSD patients

Repeated intravenous (IV) ketamine infusions significantly reduce symptom severity in individuals with chronic post-traumatic stress disorder (PTSD) and the improvement is rapid and maintained for several weeks afterwards, according to a study conducted by researchers from the Icahn School of Medicine at Mount Sinai.

5 Jan 2021

Increased pollen counts may trigger symptom flares in patients with urologic chronic pelvic pain syndrome

As anyone living with hay fever can attest, days with high pollen counts can bring attacks of sneezing, nasal congestion and other allergy symptoms.

5 Jan 2021

Replacing the RNA strand with DNA may enhance efficacy of ASO-based drugs

Antisense oligonucleotides (ASO) hold great promise for pharmacotherapy. Now, researchers at Tokyo Medical and Dental University (TMDU) and Ionis Pharmaceuticals, advancing their earlier work on a heteroduplex oligonucleotide (HDO) model, have demonstrated augmentation of ASO-based drugs by replacing the RNA strand with DNA.

5 Jan 2021

Novel imaging method reveals in vivo localization of antibiotics in infected lung tissues

Researchers at the Francis Crick Institute and the University of Western Australia have developed a new imaging method to see where antibiotics have reached bacteria within tissues.

5 Jan 2021

Hospital prices just got a lot more transparent. What does this mean for you?

Hospitals face the new year with new requirements to post price information they have long sought to obscure: the actual prices negotiated with insurers and the discounts they offer their cash-paying customers.

5 Jan 2021

Many health plans now must cover full cost of expensive HIV prevention drugs

Ted Howard started taking Truvada a few years ago because he wanted to protect himself against HIV, the virus that causes AIDS. But the daily pill was so pricey he was seriously thinking about giving it up.

5 Jan 2021

Neuroscientists track gene expression to gain insights into drug addiction, Parkinson's disease

Two MIT neuroscientists have received grants from the G. Harold and Leila Y. Mathers Foundation to screen for genes that could help brain cells withstand Parkinson's disease and to map how gene expression changes in the brain in response to drugs of abuse.

4 Jan 2021

Researchers resolve mysteries about the function of key gene-silencing protein

A long-running debate over how an important gene-silencing protein identifies its targets has been resolved by researchers at Massachusetts General Hospital (MGH).

4 Jan 2021

$Prolactin triggers male refractory period, indicates study$

Prolactin triggers male refractory period, indicates study

If you type into a search engine - "why do men have to wait before having sex again?" - you will very quickly come across Prolactin. This little hormone is thought to be involved in hundreds of physiological processes in the body. Among them is the male post-ejaculatory refractory period. This period begins when a male ejaculates and ends when he recovers his sexual capacity.

4 Jan 2021

Research offers clues on why pregnancy may raise risk of organ transplant rejection

A research study at the University of Chicago has found that in pregnancy, while the T cell response to a fetus becomes tolerant to allow for successful pregnancy, the part of the immune system that produces antibodies (known as the humoral response) becomes sensitized, creating memory B cells that can later contribute to the rejection of a transplanted organ.

4 Jan 2021

Drugs News and Research

Researchers receive $2.1 million NIH grant to study causes of congenital heart defects

Inhibition of blood clotting factor reduces the formation of brain metastases in mice

Repeated ketamine infusions may be a promising treatment for PTSD patients

Increased pollen counts may trigger symptom flares in patients with urologic chronic pelvic pain syndrome

Replacing the RNA strand with DNA may enhance efficacy of ASO-based drugs

Novel imaging method reveals in vivo localization of antibiotics in infected lung tissues

Hospital prices just got a lot more transparent. What does this mean for you?

Many health plans now must cover full cost of expensive HIV prevention drugs

Neuroscientists track gene expression to gain insights into drug addiction, Parkinson's disease

Researchers resolve mysteries about the function of key gene-silencing protein

Prolactin triggers male refractory period, indicates study

Research offers clues on why pregnancy may raise risk of organ transplant rejection

USF researchers discover promising new compound to open constricted airways

Epigenetic modulators have a rapid antidepressant-like effect, study shows

Machine-learning method can crunch data to find new uses for existing drugs

Tissue healing after brain injury could spur tumor growth

FDA takes first steps in bringing clarity to emerging area of individualized drug development

Seniors face crushing drug costs as Congress stalls on capping Medicare out-of-pockets

Children’s hospitals are partly to blame as superbugs increasingly attack kids

Biologist receives NIH grant to build software tools to predict cancer drug efficacy

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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