Drugs News and Research

RSS

P2 COVID-19 study shows no material safety differences between opaganib and control arms

Preliminary data from the non-powered U.S. Phase 2 study of 40 hospitalized patients shows that orally-administered opaganib was safe, with no material safety differences between opaganib and control arms.

4 Jan 2021

People who move due to unaffordable housing may not receive medical care

People who move due to unaffordable housing are at increased risk of failing to receive the medical care they need, according to a new study from Cedars-Sinai and the University of California, Los Angeles.

4 Jan 2021

Researchers identify traditional Ghanaian medicines to eradicate neglected tropical diseases

The discovery of new drugs is vital to achieving the eradication of neglected tropical diseases (NTDs) in Africa and around the world.

4 Jan 2021

FDA-approved COVID-19 drug should be used cautiously, says UC researcher

While the world has its eyes on vaccines to stop the spread of coronavirus, therapeutics are still necessary to treat hospitalized patients. One of these treatments, remdesivir, is the first and only antiviral agent of its kind that the U.S. Food and Drug Administration (FDA) has approved so far for COVID-19.

3 Jan 2021

Protein employs twist‐and‐squeeze mechanism to expel chemotherapeutics from cancer cells

In 1986, cellular biochemist Kazumitsu Ueda, currently at Kyoto University's Institute for Integrated Cell-Material Sciences, discovered that a protein called ABCB1 could transport multiple chemotherapeutics out of some cancer cells, making them resistant to treatment. How it did this has remained a mystery for the past 35 years.

29 Dec 2020

Toxic pesticide turned into treatment against antibiotic-resistant bacteria

N-Aryl-C-nitroazoles are an important class of heterocyclic compounds. They are used as pesticides and fungicides. However, these substances could be toxic to humans and cause mutations.

29 Dec 2020

Anesthesia and sleep have surprisingly similar effects on brain activity, finds study

What happens in the brain when our conscious awareness fades during general anesthesia and normal sleep? Finnish scientists studied this question with novel experimental designs and functional brain imaging.

29 Dec 2020

FDA approves first generic glucagon for injection to treat severe hypoglycemia

Today, the U.S. Food and Drug Administration approved the first generic of glucagon for injection USP, 1 mg/vial packaged in an emergency kit, for the treatment of severe hypoglycemia (very low blood sugar), which may occur in patients with diabetes mellitus.

28 Dec 2020

Researchers discover how chromosomal instability allows cancer cells to avoid immune defenses

Cancer cells are known for spreading genetic chaos. As cancer cells divide, DNA segments and even whole chromosomes can be duplicated, mutated, or lost altogether. This is called chromosomal instability, and scientists at Memorial Sloan Kettering have learned that it is associated with cancer's aggressiveness.

28 Dec 2020

Phase 3 trial of Novavax COVID-19 vaccine candidate begins enrolling volunteers

The Phase 3 trial of another investigational coronavirus disease 2019 (COVID-19) vaccine has begun enrolling adult volunteers.

28 Dec 2020

Researchers develop new drug discovery method targeting membrane proteins on live cells

A research team led by Dr Xiaoyu LI from the Research Division for Chemistry, Faculty of Science, in collaboration with Professor Yizhou LI from School of Pharmaceutical Sciences, Chongqing University and Professor Yan CAO from School of Pharmacy, Second Military Medical University in Shanghai has developed a new drug discovery method targeting membrane proteins on live cells.

28 Dec 2020

Study identifies the effects of malnutrition on patient survival after cardiac surgery

Nutrients are the structural components of food that the body needs to function properly. They are divided into macronutrients (proteins, fats, carbohydrates) and micronutrients (vitamins, provitamins, various minerals, and so on). Their shortage is called nutritional deficiency.

28 Dec 2020

Popular glucose-lowering drug may cause rare diabetes complication in COVID-19 patients

Diabetes is a known risk factor for morbidity and mortality related to COVID-19. In diabetes patients, rare but severe complications, like the potentially lethal condition diabetic ketoacidosis (DKA), can arise when illness or certain conditions prevent cells from receiving enough glucose to fuel their functioning.

28 Dec 2020

Kobe University and Sysmex conduct joint research on ELISPOT method for identifying COVID-19

Kobe University and Sysmex Corporation have been engaged in joint research on the ELISPOT method, a new blood test for identifying the novel coronavirus disease (COVID-19).

24 Dec 2020

Study reveals how ecDNA fragments drive gene amplification to generate drug resistance in cancer

Researchers led by Ludwig San Diego Member Don Cleveland and Peter Campbell of the Sanger Center have solved the mystery of how free-floating circular DNA fragments, which are almost exclusively found in cancer cells, drive gene amplification to generate drug resistance in cancer.

24 Dec 2020

Researchers discover how shattered chromosomes make cancer cells more aggressive

Cancer is one of the world's greatest health afflictions because, unlike some diseases, it is a moving target, constantly evolving to evade and resist treatment.

23 Dec 2020

Researchers identify new weapon to battle the rising tide of antibiotic-resistant bacteria

As scientists around the globe wage war against a novel, deadly virus, one University of Colorado Boulder lab is working on new weapons to battle a different microbial threat: a rising tide of antibiotic-resistant bacteria which, if left unchecked, could kill an estimated 10 million people annually by 2050.

23 Dec 2020

New tool may help monitor serotonin transmission with greater fidelity than current methods

Serotonin is a neurochemical that plays a critical role in the way the brain controls our thoughts and feelings.

23 Dec 2020

FDA takes further steps to strengthen REMS program to confront opioid crisis

While our efforts to combat COVID-19 remain at the forefront of our day-to-day activities, the U.S. Food and Drug Administration also continues its work on a number of important public health issues and, in particular, the opioid crisis.

23 Dec 2020

FDA authorizes first device to treat patients with walled-off pancreatic necrosis

Today, the U.S. Food and Drug Administration authorized marketing of the EndoRotor System to resect (cut out) and remove necrotic (dead) tissue for patients with walled-off pancreatic necrosis (WOPN), a potentially deadly condition which can occur several weeks after an episode of severe acute pancreatitis, often requiring tissue removal.

23 Dec 2020

Drugs News and Research

P2 COVID-19 study shows no material safety differences between opaganib and control arms

People who move due to unaffordable housing may not receive medical care

Researchers identify traditional Ghanaian medicines to eradicate neglected tropical diseases

FDA-approved COVID-19 drug should be used cautiously, says UC researcher

Protein employs twist‐and‐squeeze mechanism to expel chemotherapeutics from cancer cells

Toxic pesticide turned into treatment against antibiotic-resistant bacteria

Anesthesia and sleep have surprisingly similar effects on brain activity, finds study

FDA approves first generic glucagon for injection to treat severe hypoglycemia

Researchers discover how chromosomal instability allows cancer cells to avoid immune defenses

Phase 3 trial of Novavax COVID-19 vaccine candidate begins enrolling volunteers

Researchers develop new drug discovery method targeting membrane proteins on live cells

Study identifies the effects of malnutrition on patient survival after cardiac surgery

Popular glucose-lowering drug may cause rare diabetes complication in COVID-19 patients

Kobe University and Sysmex conduct joint research on ELISPOT method for identifying COVID-19

Study reveals how ecDNA fragments drive gene amplification to generate drug resistance in cancer

Researchers discover how shattered chromosomes make cancer cells more aggressive

Researchers identify new weapon to battle the rising tide of antibiotic-resistant bacteria

New tool may help monitor serotonin transmission with greater fidelity than current methods

FDA takes further steps to strengthen REMS program to confront opioid crisis

FDA authorizes first device to treat patients with walled-off pancreatic necrosis

Industry Focus eBook - Cell biology (5th edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Latest News