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Dengue vaccine may worsen infections if used in areas with low rates of disease

The world's only licensed vaccine for dengue may worsen subsequent dengue infections if used in areas with low rates of dengue infection, suggests new research.

6 Sep 2016

Study examines effectiveness of spiritual meditation plus medication intervention for migraines

"Effect of Different Meditation Types on Migraine Headache Medication Use," an article recently published in Behavioral Medicine, examines whether or not, and to what extent, a combination of spiritual meditation and migraine medication affects analgesic medication usage.

2 Sep 2016

New study provides insights into how regulators support accelerated access to new therapies

It can be challenging for regulators to keep up with advances related to medical drugs and devices. A new analysis and editorial published in the British Journal of Clinical Pharmacology provide insights on how officials are working to support accelerated access to new therapies while also ensuring their safety.

2 Sep 2016

Chemists find efficient way to convert organic molecules into new medicines

Opening a broad vista in the search for effective pharmaceuticals, a collaboration of Chinese and U.S. chemists has laid out a highly efficient new method to convert abundant organic molecules into new medicines.

2 Sep 2016

RIT professor receives federal award for research to help combat threat of antibiotic-resistant bacteria

A Rochester Institute of Technology professor has received a federal award for research that could help in the critical battle to develop new drugs to combat the drastic rise in the number of antibiotic-resistant bacteria.

2 Sep 2016

UCR researcher creating first reading intervention program designed for children with ASD

If you can't understand them, the words on this page have no meaning. They can't share a new fact, they can't bring you pleasure and they can't provide the information you need to function in life.

1 Sep 2016

Research findings of protein may form foundation for new approach to antibiotics

Researchers have made the first-ever detailed, atomic-level images of a peroxiredoxin, which has revealed a peculiar characteristic of this protein and might form the foundation for a new approach to antibiotics.

1 Sep 2016

Monoclonal antibody removes brain amyloid plaques in patients with Alzheimer's disease

Scientists at Neurimmune today described results from the Phase 1b PRIME clinical trial of the monoclonal antibody aducanumab.

1 Sep 2016

Simple diagnostic algorithm to assess pulmonary embolism risk can help reduce rate of CTPA imaging

Patients with suspected pulmonary embolism (PE) often undergo computed tomography pulmonary angiography (CTPA) to confirm or exclude the diagnosis.

31 Aug 2016

Transplantation of placenta-derived MSCs can prevent diabetes-related CLI in rats

In an effort to determine if stem cell therapy can prevent or improve a condition called "diabetic foot" caused by poor blood flow in patients with diabetes, a team of researchers in China has found that transplanting human placenta-derived mesenchymal stem cells (MSCs) into rats modeled with diabetes can affect blood vessel growth, potentially improving blood flow and preventing critical limb ischemia (CLI), a condition that results in diabetic foot and frequently leads to amputation.

30 Aug 2016

New anticoagulant treatment safe and effective for AF patients before cardioversion

Patients with atrial fibrillation (AF) who need anticoagulation before undergoing electrical correction of their abnormal heartbeat (cardioversion) may benefit from treatment with edoxoban - a non-vitamin K antagonist (VKA) oral anticoagulant (NOAC), according to results of the ENSURE-AF trial.

30 Aug 2016

Novel drug delivery system may offer new hope for patients with rare fatal genetic disorder

Researchers at Oregon State University and other institutions have discovered a type of drug delivery system that may offer new hope for patients with a rare, ultimately fatal genetic disorder - and make what might become a terrible choice a little easier.

30 Aug 2016

New generation drug eluting stents show lower efficacy than contemporary BMS, study shows

New generation drug eluting stents (new DES) did not outshine contemporary bare metal stents (BMS) as they were expected to, in a surprise finding of the largest randomized stent trial to date.

30 Aug 2016

Novel antidote effective in quickly reversing acute anticoagulant-related bleeding

A specially designed antidote to reverse acute, potentially life-threatening anticoagulant-related bleeding worked quickly, and was well-tolerated according to interim results of the ongoing ANNEXA-4 study.

30 Aug 2016

Physicians vary greatly in their responses to patients about e-cigarettes, study reveals

If you ask two different doctors about e-cigarettes, you might get two different answers.

30 Aug 2016

NCATS scientists identify promising compounds effective in inhibiting Zika virus replication

Researchers at the National Center for Advancing Translational Sciences recently identified compounds that potentially can be used to inhibit Zika virus replication and reduce its ability to kill brain cells.

29 Aug 2016

Novel drug-dispensing contact lens effective in providing better pressure reduction in glaucoma model

A contact lens designed to deliver medication gradually to the eye could improve outcomes for patients with conditions requiring treatment with eye drops, which are often imprecise and difficult to self-administer.

29 Aug 2016

Less invasive infusion strategy not linked to cardiac functional improvements but enhances health status

A single dose of mesenchymal stem cells delivered intravenously to patients with chronic non-ischemic cardiomyopathy was not associated with significant cardiac structural or functional improvements, but did result in several clinically relevant benefits, according to results from a phase II-a randomized trial.

29 Aug 2016

Large cardiopoietic regenerative therapy trial for patients with congestive heart failure reveals new insights

A therapy that uses bone-marrow stem cells to promote heart repair did not significantly improve the primary outcome over a sham procedure among patients with congestive heart failure.

29 Aug 2016

Leading Chikungunya vaccine in clinical trial phase 2

With the first patient vaccinated, a Phase 2 clinical trial of a promising prophylactic vaccine candidate against Chikungunya fever has now commenced. The product is the most advanced Chikungunya vaccine candidate globally and is developed by the Austrian biotech company Themis Bioscience GmbH.

29 Aug 2016

Efficacy News and Research

Dengue vaccine may worsen infections if used in areas with low rates of disease

Study examines effectiveness of spiritual meditation plus medication intervention for migraines

New study provides insights into how regulators support accelerated access to new therapies

Chemists find efficient way to convert organic molecules into new medicines

RIT professor receives federal award for research to help combat threat of antibiotic-resistant bacteria

UCR researcher creating first reading intervention program designed for children with ASD

Research findings of protein may form foundation for new approach to antibiotics

Monoclonal antibody removes brain amyloid plaques in patients with Alzheimer's disease

Simple diagnostic algorithm to assess pulmonary embolism risk can help reduce rate of CTPA imaging

Transplantation of placenta-derived MSCs can prevent diabetes-related CLI in rats

New anticoagulant treatment safe and effective for AF patients before cardioversion

Novel drug delivery system may offer new hope for patients with rare fatal genetic disorder

New generation drug eluting stents show lower efficacy than contemporary BMS, study shows

Novel antidote effective in quickly reversing acute anticoagulant-related bleeding

Physicians vary greatly in their responses to patients about e-cigarettes, study reveals

NCATS scientists identify promising compounds effective in inhibiting Zika virus replication

Novel drug-dispensing contact lens effective in providing better pressure reduction in glaucoma model

Less invasive infusion strategy not linked to cardiac functional improvements but enhances health status

Large cardiopoietic regenerative therapy trial for patients with congestive heart failure reveals new insights

Leading Chikungunya vaccine in clinical trial phase 2

Industry Focus eBook - Neurology/Neuroscience - 2nd edition eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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