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Major anti-cancer protein released by neutrophils selectively kills tumor cells

A study published in the June 10, 2021 issue of Cell describes a remarkable new mechanism by which the body's own immune system can eliminate cancer cells without damaging host cells.

10 Jun 2021

$Middle-aged men with cerebral palsy more likely to suffer fractures, study finds$

Middle-aged men with cerebral palsy more likely to suffer fractures, study finds

Researchers at Michigan Medicine found a subset of middle-aged men with cerebral palsy are up to 5.6 times more likely to suffer fractures than men without the disorder.

10 Jun 2021

ACTG launches phase 1 HIV cure study evaluating two promising therapies

The AIDS Clinical Trials Group, the largest global HIV research network, today announced the launch of A5386, a phase 1 HIV cure study evaluating two promising therapies.

10 Jun 2021

CPAP use by sleep apnea patients associated with lower cardiovascular risk

Findings from a recent study show that patients with untreated, moderate to severe obstructive sleep apnea had a higher risk of experiencing a cardiovascular event, but the risk of incident heart problems was decreased in those who used CPAP therapy.

10 Jun 2021

LIM domain only 1 gene contributes to the tumorigenesis of multiple cancers

Humans have been plagued by a myriad of deadly cancers since ages. Parallelly, they have also been attempting different permutations and combinations of treatments to cure the disease. Part of these attempts involving biomolecular targets have come to the fore in recent years.

10 Jun 2021

Social support, age associated with remission from alcohol dependence and optimal mental health

New research published online in the journal Substance Use & Misuse is good news for those struggling with alcohol dependence: the possibility of ending this dependency gets easier with age.

10 Jun 2021

Common antidepressant drugs help the immune system to attack tumors in mice

A class of drug called monoamine oxidase inhibitors is commonly prescribed to treat depression; the medications work by boosting levels of serotonin, the brain's "happiness hormone."

10 Jun 2021

Can a subscription model fix primary care in the US?

In April, San Francisco-based primary care company One Medical revealed an eye-popping compensation package for its chief executive and chairman, Amir Dan Rubin. His $199 million payday, particularly noteworthy at a company that has yet to turn a profit, made Rubin the second-highest-paid CEO in the United States last year — but only on paper.

10 Jun 2021

Local anesthetic procaine inhibits SARS-CoV-2 in vitro

Research has shown that procaine and procaine-hydrochloride can reduce replication of SARS-CoV-2 and influenza A viruses in infected cells and reduce the production of cytokines by the viruses, making them potentially useful for treating COVID-19.

10 Jun 2021

Nose-to-brain: Nasal delivery of biopharmaceuticals to the brain

Placing medications as close as possible to the site of the disease: This sounds completely believable in theory, but is unfortunately not so simple in practice. While this works well for many drugs via the bloodstream or the digestive tract, it does not apply to the brain.

9 Jun 2021

Study: COVID-19 vaccines safe for IBD patients

Patients with inflammatory bowel diseases (IBD) do not appear to have increased risk of side effects from the Pfizer or Moderna COVID-19 vaccines, according to a recent Cedars-Sinai study published online and upcoming in print in the American Journal of Gastroenterology.

9 Jun 2021

FDA releases draft guidance on measuring patient-reported outcomes in cancer clinical trials

The following quote is attributed to Richard Pazdur, M.D., director of the FDA's Oncology Center of Excellence and acting director of the Office of Oncologic Diseases in the FDA's Center for Drug Evaluation and Research.

9 Jun 2021

Researchers identify a common mechanism underlying diverse brain disorders

Researchers at Vanderbilt University Medical Center have identified a common mechanism underlying a spectrum of epilepsy syndromes and neurodevelopmental disorders, including autism, that are caused by variations in a gene encoding a vital transporter protein in the brain.

9 Jun 2021

Clinical trial investigates effectiveness of delivering HIV, substance use care through mobile clinics

A clinical trial is underway in five U.S. cities to determine whether delivering integrated health services through mobile clinics can improve HIV and substance use outcomes among people with opioid use disorder who inject drugs.

9 Jun 2021

Pathogenic airway neutrophilia drives ARDS in Black patients with severe COVID-19 in case study

Researchers from the US used a systems immunology approach where they combined high-dimensional flow cytometry and multi-omics single-cell sequencing analyses of immune profiles taken from the airways and matching blood samples of Black/AA patients.

9 Jun 2021

Nintendo Wii therapy can help improve balance in children with cerebral palsy

Therapy based on the Nintendo® Wii Balance Board can help improve balance in children with cerebral palsy, according to an analysis published in Developmental Medicine & Child Neurology.

9 Jun 2021

QurAlis gears up for clinical development of therapeutic candidate, QRL-101

(BUSINESS WIRE)--QurAlis Corporation, a biotech company developing breakthrough precision medicines for ALS and other genetically validated neurodegenerative diseases, today announced the publication of an article in Cell Reports.

9 Jun 2021

Vascular preservation therapy eliminates the varicose vein problem

Rather than destroying or removing defective veins, it is possible to repair them by using a sheath. They are thus saved for later use as a bypass.

8 Jun 2021

Researchers clarify cellular processes related to radiation resistance of pancreatic cancer cells

Pancreatic cancer is one of the deadliest cancer subtypes not just because it is difficult to diagnose early, but because it is inherently resistant to chemotherapy and radiotherapy.

8 Jun 2021

Researchers uncover new gene mutation responsible for cerebral cavernous malformation

Researchers from the Hong Kong University of Science and Technology and Beijing Tiantan Hospital have recently uncovered a new gene mutation responsible for the non-familial patients of cerebral cavernous malformation (CCM) - a brain vascular disorder which inflicted about 10~30 million people in the world.

8 Jun 2021

Therapy News and Research

Major anti-cancer protein released by neutrophils selectively kills tumor cells

Middle-aged men with cerebral palsy more likely to suffer fractures, study finds

ACTG launches phase 1 HIV cure study evaluating two promising therapies

CPAP use by sleep apnea patients associated with lower cardiovascular risk

LIM domain only 1 gene contributes to the tumorigenesis of multiple cancers

Social support, age associated with remission from alcohol dependence and optimal mental health

Common antidepressant drugs help the immune system to attack tumors in mice

Can a subscription model fix primary care in the US?

Local anesthetic procaine inhibits SARS-CoV-2 in vitro

Nose-to-brain: Nasal delivery of biopharmaceuticals to the brain

Study: COVID-19 vaccines safe for IBD patients

FDA releases draft guidance on measuring patient-reported outcomes in cancer clinical trials

Researchers identify a common mechanism underlying diverse brain disorders

Clinical trial investigates effectiveness of delivering HIV, substance use care through mobile clinics

Pathogenic airway neutrophilia drives ARDS in Black patients with severe COVID-19 in case study

Nintendo Wii therapy can help improve balance in children with cerebral palsy

QurAlis gears up for clinical development of therapeutic candidate, QRL-101

Vascular preservation therapy eliminates the varicose vein problem

Researchers clarify cellular processes related to radiation resistance of pancreatic cancer cells

Researchers uncover new gene mutation responsible for cerebral cavernous malformation

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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