B Cell News and Research

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Study defines how cannabis cells make cannabinoids

For the first time, plant biologists have defined the high-efficiency "hacks" that cannabis cells use to make cannabinoids (THC/CBD). Although many biotechnology companies are currently trying to engineer THC/CBD outside the plant in yeast or cell cultures, it is largely unknown how the plant does it naturally.

3 Aug 2022

Drugs with antiviral activity against monkeypox virus

In a recent study posted as an accepted manuscript in the journal Clinical Infectious Diseases, researchers from the University of Oklahoma described three drugs with antiviral activity against the monkeypox virus (MPXV).

2 Aug 2022

Experiments and mathematical modeling help study the role of morphogens in tissue patterning

Morphogens are molecules that travel from biological cell to cell to pattern tissues in the embryo. These molecules are important not only for the embryo during development, but also for the adult during tissue repair.

2 Aug 2022

Novel algorithm provides rich, detailed information on protein location and function within a cell

Humans are good at looking at images and finding patterns or making comparisons. Look at a collection of dog photos, for example, and you can sort them by color, by ear size, by face shape, and so on. But could you compare them quantitatively? And perhaps more intriguingly, could a machine extract meaningful information from images that humans can't?

2 Aug 2022

Neurons show rhythmic activity at different frequencies in the desynchronized state

In the 17th century, the Dutch scientist Christiaan Huygens hanged two of his recently invented pendulum clocks on a wooden beam and observed that as time passed, the clocks aligned their beats.

2 Aug 2022

Jianhua Zhao secures $2.4 million NIGMS grant to study the molecular machinery of proteolysis

Assistant Professor Jianhua Zhao, Ph.D., has been awarded a unique and competitive grant from the National Institute of General Medical Sciences, part of the National Institutes of Health.

2 Aug 2022

Timothy Huang receives $2.8 million to continue research on Alzheimer's disease

Timothy Huang, Ph.D., has been awarded $2.8 million by the National Institute on Aging (NIA) to continue his work on Alzheimer's disease.

2 Aug 2022

New research unravels why breastmilk-fed preemies are healthier than formula-fed infants

Human breastmilk has long been considered "liquid gold" among clinicians treating premature infants in a newborn intensive care unit.

2 Aug 2022

Research could pave the way for therapeutic strategies targeting DCIR to treat colorectal tumors

Colorectal tumors are a common adverse effect of chronic inflammation of the intestine. In a new study, researchers from Japan and China demonstrate that mice models with dendritic cell immunoreceptor (DCIR) protein deficiency are resistant to colonic tumors induced by dextran sodium sulfate and azoxymethane.

2 Aug 2022

Light-activated proteins can help normalize dysfunction within cells, study shows

New research from the University of Cincinnati shows early indications that light can be used as a treatment for certain diseases, including cancer.

2 Aug 2022

IRB Barcelona researchers discover genetic drivers of clonal hematopoiesis

Clonal hematopoiesis is a biological process in which a blood stem cell (the population that gives rise to a variety of blood cell types) acquires an advantageous mutation and outgrows neighboring cells.

2 Aug 2022

ADAR1 mutation sets off biochemical pathways that produce an organ-damaging autoimmune response

A new study shows how mutation of the ADAR1 gene sets off biochemical pathways that produce an autoimmune response that harms the developing brain and other areas of the body.

2 Aug 2022

Shear-thinning biomaterial-based minimally invasive strategy for delivery of targeted immunotherapy

Researchers at the Terasaki Institute for Biomedical Innovation (TIBI) have developed and optimized a minimally invasive method for more targeted, efficient, and sustained delivery of immunotherapeutic treatments for cancer.

2 Aug 2022

TransCode and MD Anderson scientists collaborate to validate therapeutic and diagnostic candidates

The University of Texas MD Anderson Cancer Center and TransCode Therapeutics, Inc. today announced a strategic alliance to advance TransCode's pipeline of RNA-targeted oncology therapeutic and diagnostic candidates.

2 Aug 2022

Study explores differential antibody-mediated effector functions evoked by two mRNA-based COVID-19 vaccines

Researchers evaluated the differential humoral immune response to two COVID-19 vaccines - messenger ribonucleic acid (mRNA)-1273 and BNT162b2.

2 Aug 2022

Pediatric adjuvant formulation offers protection against RSV in newborns

Respiratory syncytial virus (RSV) is the leading global cause of death in children under age 5 and lacks an effective vaccine. In a study from the Precision Vaccines Program at Boston Children's Hospital, a new vaccine formulation protected newborn mice against infection and evoked strong responses in immune cells from human newborns in the laboratory. Results were reported August 2 in Nature Communications.

2 Aug 2022

B Cell News and Research

Study defines how cannabis cells make cannabinoids

Drugs with antiviral activity against monkeypox virus

Experiments and mathematical modeling help study the role of morphogens in tissue patterning

Novel algorithm provides rich, detailed information on protein location and function within a cell

Neurons show rhythmic activity at different frequencies in the desynchronized state

Jianhua Zhao secures $2.4 million NIGMS grant to study the molecular machinery of proteolysis

Timothy Huang receives $2.8 million to continue research on Alzheimer's disease

New research unravels why breastmilk-fed preemies are healthier than formula-fed infants

Research could pave the way for therapeutic strategies targeting DCIR to treat colorectal tumors

Light-activated proteins can help normalize dysfunction within cells, study shows

IRB Barcelona researchers discover genetic drivers of clonal hematopoiesis

ADAR1 mutation sets off biochemical pathways that produce an organ-damaging autoimmune response

Shear-thinning biomaterial-based minimally invasive strategy for delivery of targeted immunotherapy

TransCode and MD Anderson scientists collaborate to validate therapeutic and diagnostic candidates

Study explores differential antibody-mediated effector functions evoked by two mRNA-based COVID-19 vaccines

Pediatric adjuvant formulation offers protection against RSV in newborns

Plasma myosin light chain 9 levels may be better predictor of COVID-19 severity than blood biomarkers

Study suggests peimine may be a potent inhibitor of SARS-CoV-2 variant infection

mRNA vaccines induce faster antibody response against infectious diseases

The efficacy of honokiol in inhibiting SARS-CoV-2 replication in cell culture

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