Immune System News and Research

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Gut may play key role in preventing Parkinson's disease

Your gut may play a pivotal role in preventing the onset of Parkinson's disease. And the reason may be its knack for sleuthing.

5 Oct 2016

JAK inhibitors show promise in restoring hair growth in patients with alopecia areata

Seventy-five percent of patients with moderate to severe alopecia areata--an autoimmune disease that causes patchy, and less frequently, total hair loss--had significant hair regrowth after treatment with ruxolitinib, reported researchers from Columbia University Medical Center. By the end of their treatment, average hair regrowth was 92 percent.

5 Oct 2016

Structural instability in myelin membranes may instigate multiple sclerosis

Multiple sclerosis is one of the most devastating neurodegenerative diseases. It affects some 2.5 million people worldwide. It has no known cure.

5 Oct 2016

Study opens door towards personalized medicine for children with eczema

Atopic dermatitis, or eczema, is a common skin disorder that usually starts by 5 years of age, but virtually all of the studies that have defined the immune changes underlying eczema and are directing new treatment options have been done in adult skin.

5 Oct 2016

Two Zika vaccine candidates protect newborn mice against neurological damage

Two vaccines against Zika virus developed at the University of Pittsburgh School of Medicine have successfully conveyed immunity from female mice to pups conceived weeks after the mother's vaccination.

4 Oct 2016

Study shows how common intestinal microbe protects the gut from attack by harmful bacteria

Antibiotics save millions of lives. But their tendency to kill helpful and harmful bacteria alike, coupled with the growing problem of antibiotic resistance, means that they are not without their downside.

4 Oct 2016

Can vitamin D reduce asthma attacks? An interview with Professor Adrian Martineau

In the past vitamin D was just thought to be important in regulating calcium homeostasis and bone health as vitamin D deficiency is best known for causing rickets in children and osteomalacia in adults.

4 Oct 2016

Discovery of rare flu-thwarting mutation could provide new strategy for live influenza vaccines

A rare and improbable mutation in a protein encoded by an influenza virus renders the virus defenseless against the body's immune system. This University of Rochester Medical Center discovery could provide a new strategy for live influenza vaccines in the future.

4 Oct 2016

Columbia researchers discover genes that may cause gum disease

Researchers at Columbia University College of Dental Medicine Columbia University Medical Center have identified 41 master regulator genes that may cause gum disease, also known as periodontal disease. The study was the first of its kind to employ genome-wide reverse engineering to identify the gene pathways that contribute to periodontitis.

4 Oct 2016

Antibody protection may help control infection caused by TB bacteria

A study led by investigators from the Ragon Institute of MGH, MIT and Harvard finds evidence that antibody protection may help control infection with the bacteria that causes tuberculosis (TB).

4 Oct 2016

Researchers move one step closer to developing effective universal flu vaccine

Researchers at McMaster University and two American universities have taken another step closer to developing a much more effective, "one-punch" universal flu vaccine.

4 Oct 2016

ACMSD enzyme could become key target for new drugs aimed at preventing suicide

An enzyme called ACMSD—part of a chain of biochemical reactions called the kynurenine pathway, activated by inflammation—could become an important target for new drugs aimed at preventing suicide.

3 Oct 2016

New study finds nearly 50% of service members with obesity experience weight stigma

Weight discrimination is a major issue in our society and in the U.S. military, service members are not immune to it. According to a new study published Sept. 26 in the APA journal, Stigma and Health, nearly 50 percent of service members who are overweight or obese have experienced it.

3 Oct 2016

Research identifies potential treatment target for chemoresistant cancer cells

A team of researchers has discovered that chemoresistant lung cancer cells suppress immune functions and strengthen resistance to chemotherapy by producing interleukin-34 (IL-34)—a type of cytokine.

3 Oct 2016

Study suggests targeting UNG enzyme may help treat non-Hodgkin's lymphoma

Researchers have discovered that an enzyme called uracil-DNA glycosylase (UNG) protects the ends of B cell chromosomes to facilitate the proliferation of these antibody-producing cells in response to infection.

3 Oct 2016

Researchers uncover pneumonia causing bacteria as trigger for autoimmune disease GBS

Guillain-Barré syndrome (GBS) is an acute life-threatening disease of the nervous system that leads to sensory disturbances and acute flaccid paralysis.

3 Oct 2016

Household dust exposes people to potentially harmful chemicals, study finds

Household dust exposes people to a wide range of toxic chemicals from everyday products, according to a study led by researchers at Milken Institute School of Public Health at the George Washington University.

3 Oct 2016

Inhibiting single protein could help restore sensitivity to common treatment for breast cancer

A team of investigators led by researchers at Georgetown Lombardi Comprehensive Cancer Center has found, in animal models of human breast cancer, that inhibiting a single protein restores sensitivity to tamoxifen, a commonly used drug for treatment of some breast cancers.

3 Oct 2016

Research shows how new ovarian cancer treatment could help boost anti-tumor immunity

Few effective treatments have been approved to treat ovarian cancer, the deadliest of all cancers affecting the female reproductive system.

3 Oct 2016

New study reveals CAR T cells can function as micro-pharmacies for precise therapeutic delivery

There has been much recent excitement about immunotherapy and the use of genetically engineered chimeric antigen receptor (CAR) T cells.

30 Sep 2016

Immune System News and Research

Gut may play key role in preventing Parkinson's disease

JAK inhibitors show promise in restoring hair growth in patients with alopecia areata

Structural instability in myelin membranes may instigate multiple sclerosis

Study opens door towards personalized medicine for children with eczema

Two Zika vaccine candidates protect newborn mice against neurological damage

Study shows how common intestinal microbe protects the gut from attack by harmful bacteria

Can vitamin D reduce asthma attacks? An interview with Professor Adrian Martineau

Discovery of rare flu-thwarting mutation could provide new strategy for live influenza vaccines

Columbia researchers discover genes that may cause gum disease

Antibody protection may help control infection caused by TB bacteria

Researchers move one step closer to developing effective universal flu vaccine

ACMSD enzyme could become key target for new drugs aimed at preventing suicide

New study finds nearly 50% of service members with obesity experience weight stigma

Research identifies potential treatment target for chemoresistant cancer cells

Study suggests targeting UNG enzyme may help treat non-Hodgkin's lymphoma

Researchers uncover pneumonia causing bacteria as trigger for autoimmune disease GBS

Household dust exposes people to potentially harmful chemicals, study finds

Inhibiting single protein could help restore sensitivity to common treatment for breast cancer

Research shows how new ovarian cancer treatment could help boost anti-tumor immunity

New study reveals CAR T cells can function as micro-pharmacies for precise therapeutic delivery

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