Immune Response News and Research

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Study finds short-term side effects of COVID-19 mRNA vaccines boost long-term antibody response

Short-term adverse effects of COVID-19 mRNA vaccinations are linked to higher and longer-lasting neutralizing antibody responses, indicating robust immune efficacy.

11 Jun 2024

Precision medicine in sepsis care: Identifying and treating the PHES subgroup in children

Sepsis – the leading cause of mortality in children around the world – can present with a wide range of signs and symptoms, making a one-size-fits-all treatment strategy ineffective.

11 Jun 2024

Attenuated virus helps eliminate cancer in mice

Northwestern Medicine scientists have discovered that an attenuated (weakened) virus can help eliminate cancer in mice.

11 Jun 2024

Patient perspectives highlight urgent need for research on smell and taste disorders

Researchers and patient advocates from the Monell Chemical Senses Center, Smell and Taste Association of North America (STANA), and Thomas Jefferson University came together during the COVID-19 pandemic to incorporate patient voices in efforts to prioritize research areas focused on improving care for people with smell and taste disorders.

10 Jun 2024

Understanding Crohn's disease through 'mini-gut' models

Cambridge scientists have grown 'mini-guts' in the lab to help understand Crohn's disease, showing that 'switches' that modify DNA in gut cells play an important role in the disease and how it presents in patients.

10 Jun 2024

Transforming antibody drug discovery with Epitope Binning-seq

Monoclonal antibodies are crucial therapeutics due to their high specificity and binding affinity for epitopes (the precise sites where an antibody attaches itself to an antigen, triggering an immune response).

10 Jun 2024

Transplanted gut microbes from aged mice trigger inflammation in young germ-free mice

When scientists transplanted the gut microbes of aged mice into young "germ-free" mice - raised to have no gut microbes of their own - the recipient mice experienced an increase in inflammation that parallels inflammatory processes associated with aging in humans.

10 Jun 2024

How Epstein-Barr virus shapes immune responses in multiple sclerosis

Study found that EBV-specific immune responses in MS patients showed higher IgG titers and cell-mediated reactions to EBV antigens compared to healthy controls, suggesting a complex role of EBV in MS development.

9 Jun 2024

Microneedle patch holds promise for promoting hair regrowth caused by alopecia areata

Alopecia areata (AA) is an autoimmune disease characterized by hair loss, which occurs when T cells of the immune system mistakenly attack hair follicles.

8 Jun 2024

How increased mTOR activity shortens lifespan and promotes aging-related diseases

The reality of a population who is aging at an accelerated rate makes it a priority to understand what happens in the body over time, on a molecular scale.

7 Jun 2024

Targeting epigenetic enzymes in dendritic cells to improve cancer immunotherapy

Immunotherapy is one of the pillars in the fight against cancer and aims to enable the body's own immune system to fight a tumor.

7 Jun 2024

Innovative microneedle patch shows promise in treating alopecia areata

Alopecia areata (AA) is an autoimmune disease characterized by hair loss, which occurs when T cells of the immune system mistakenly attack hair follicles.

6 Jun 2024

Ultrasound technology breaks blood-brain barrier for glioblastoma treatment

In a major advance for the treatment of the deadly brain cancer glioblastoma, Northwestern Medicine scientists used ultrasound technology to penetrate the blood-brain barrier and provide a small dose of a chemotherapy and immunotherapy drug cocktail.

6 Jun 2024

New bilateral gene therapy shows promising results in treating genetic hearing loss

A novel gene therapy designed to target a form of inherited deafness restored hearing function in five children who were treated in both ears.

5 Jun 2024

Salk researchers unveil SWI/SNF variants' role in macrophage immune responses

Bacteria, parasites, viruses - the immune system tackles them all. At the front line of the human immune response are cells called macrophages, which are responsible for correctly identifying intruders and then directing how the entire immune system responds.

5 Jun 2024

JUN protein could slow prostate cancer growth, study finds

As prostate cancer progresses, it becomes increasingly aggressive and can metastasise. In this form, the tumor is difficult to treat, which is reflected in high mortality rates: Worldwide, the malignant disease of the prostate is the second most common cause of cancer death in men.

5 Jun 2024

Unraveling the role of follicular helper lymphocytes in antibody production against viruses and allergies

The production of antibodies, essential for protecting our body against infections, is very well regulated through the action of a specific subtype of immune system cells, follicular helper lymphocytes.

4 Jun 2024

Proteomic profiling reveals sexual dimorphism and immune system alterations in Werner syndrome

A new research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 10, entitled, "Integrated liver and serum proteomics uncover sexual dimorphism and alteration of several immune response proteins in an aging Werner syndrome mouse model."

4 Jun 2024

New treatment approach could offer longer lasting protection to people with breast cancer

Killing breast cancer cells in a way that trains the immune system to recognize and destroy residual cancer cells could offer longer lasting protection to people with the disease, according to new research funded by Breast Cancer Now.

3 Jun 2024

RNA virus hiding in common human parasite may exacerbate toxoplasmosis

An international team led by researchers at the University of Toronto has found a new RNA virus that they believe is hitching a ride with a common human parasite.

31 May 2024

Immune Response News and Research

Study finds short-term side effects of COVID-19 mRNA vaccines boost long-term antibody response

Precision medicine in sepsis care: Identifying and treating the PHES subgroup in children

Attenuated virus helps eliminate cancer in mice

Patient perspectives highlight urgent need for research on smell and taste disorders

Understanding Crohn's disease through 'mini-gut' models

Transforming antibody drug discovery with Epitope Binning-seq

Transplanted gut microbes from aged mice trigger inflammation in young germ-free mice

How Epstein-Barr virus shapes immune responses in multiple sclerosis

Microneedle patch holds promise for promoting hair regrowth caused by alopecia areata

How increased mTOR activity shortens lifespan and promotes aging-related diseases

Targeting epigenetic enzymes in dendritic cells to improve cancer immunotherapy

Innovative microneedle patch shows promise in treating alopecia areata

Ultrasound technology breaks blood-brain barrier for glioblastoma treatment

New bilateral gene therapy shows promising results in treating genetic hearing loss

Salk researchers unveil SWI/SNF variants' role in macrophage immune responses

JUN protein could slow prostate cancer growth, study finds

Unraveling the role of follicular helper lymphocytes in antibody production against viruses and allergies

Proteomic profiling reveals sexual dimorphism and immune system alterations in Werner syndrome

New treatment approach could offer longer lasting protection to people with breast cancer

RNA virus hiding in common human parasite may exacerbate toxoplasmosis

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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