Molecular Biology News and Research

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Molecular biology is the study of biology at a molecular level. The field overlaps with other areas of biology and chemistry, particularly genetics and biochemistry. Molecular biology chiefly concerns itself with understanding the interactions between the various systems of a cell, including the interactions between DNA, RNA and protein biosynthesis as well as learning how these interactions are regulated.

New machine learning algorithm finds a gene signature characteristic of tumors

How do cancer cells differ from healthy cells? A new machine learning algorithm called "ikarus" knows the answer, reports a team led by MDC bioinformatician Altuna Akalin in the journal Genome Biology. The AI program has found a gene signature characteristic of tumors.

10 Jun 2022

Proteomic analysis of 2002 tumors reveals 11 distinct pan-cancer molecular subtypes

A new study that analyzed protein levels in 2,002 primary tumors from 14 tissue-based cancer types identified 11 distinct molecular subtypes, providing systematic knowledge that greatly expands a searchable online database that has become a go-to platform for cancer data analysis by users worldwide.

10 Jun 2022

Creating CAR T cells without an immune brake

T cells are usually very good at eliminating diseased cells. But they seem to fail when it comes to tumor cells.

10 Jun 2022

Artificial intelligence-based computational program predicts the 3D structure of rotavirus spike protein

Of the three groups of rotavirus that cause gastroenteritis in people, called groups A, B and C, groups A and C affect mostly children and are the best characterized.

9 Jun 2022

Researchers create first comprehensive functional map of genes expressed in human cells

The Human Genome Project was an ambitious initiative to sequence every piece of human DNA. The project drew together collaborators from research institutions around the world, including Whitehead Institute, and was finally completed in 2003.

9 Jun 2022

Metrion Biosciences appoints Dr Benedetta Montagnini as Head of European Business Development

Metrion Biosciences Limited (“Metrion”), the specialist ion channel contract research and drug discovery company, today announced the appointment of Dr Benedetta Montagnini as Head of European Business Development. Driven by the uptake of its ion channel discovery services, the appointment follows the recent creation of a Client Services team as Metrion expands its operations and enhanced drug discovery capabilities, internationally.

From Metrion Biosciences Limited 9 Jun 2022

Pulmonary and primary care experts aim to reduce the time to diagnose interstitial lung diseases

The American College of Chest Physicians (CHEST) and Three Lakes Foundation are announcing a steering committee of experts in the fields of pulmonary medicine and primary care medicine to lead an initiative called Bridging Specialties™: Timely Diagnosis for ILD Patients.

9 Jun 2022

New therapeutic avoids major allergic reactions while maintaining therapeutic activity

Several years ago, a promising therapeutic using stem cell factor (SCF) emerged that could potentially treat a variety of ailments, such as ischemia, heart attack, stroke and radiation exposure.

8 Jun 2022

Irregularities in production of brain cells may lead to autism spectrum disorder, finds study

Analyzing brain stem cells of patients with autism spectrum disorder (ASD), Rutgers scientists have found evidence of irregularities in very early brain development that may contribute to the neuropsychiatric disorder.

8 Jun 2022

Phase separation discovery could lead to new interventions to regulate immune activity

Protein complexes that play a critical role in launching an immune response assemble in droplets that form within the liquid environment in cells much like oil droplets in water, UT Southwestern scientists report in a new study.

6 Jun 2022

MIT researchers identify components of mucus that can inhibit fungal infections

Candida albicans is a yeast that often lives in the human digestive tract and mouth, as well as urinary and reproductive organs.

6 Jun 2022

Neuroscientists study the formation of fear memories in the brain's emotional hub

Experiencing a frightening event is likely something you'll never forget. But why does it stay with you when other kinds of occurrences become increasingly difficult to recall with the passage of time?

1 Jun 2022

Study finds a link between aging and cancer metastases

Spreading cancer cells that escape a primary tumor site can seed in tissues distant from the tumor, but may take several years or decades to grow into full metastatic cancers.

1 Jun 2022

New findings reveal potential mechanisms for cellular defects in human laminopathies

A Northwestern Medicine study has uncovered distinct roles for major nuclear lamin isoforms in maintaining intracellular interactions and cellular mechanics, according to findings published in the Proceedings of the National Academy of Sciences.

1 Jun 2022

Study highlights the positive effects of Humanin G in reducing inflammation in AMD

A new research paper was published in Aging (Aging-US) on the cover of Volume 14, Issue 10, entitled, "Effect of Humanin G (HNG) on inflammation in age-related macular degeneration (AMD)."

31 May 2022

Understanding transposons provides a new starting point to generate more powerful gene editing tools

CRISPR has ushered in the era of genomic medicine. A line of powerful tools has been developed from the popular CRISPR-Cas9 to cure genetic diseases.

27 May 2022

Dr. Paul Brooks is CN Bio's New Chief Business Officer

CN Bio, a leading Organ-on-a-chip Company (OOC) that designs and manufactures single- and multi-organ microphysiological systems (MPS), today announced the appointment of Dr. Paul Brooks as Chief Business Officer.

From CN Bio 25 May 2022

Study unveils the novel driver of cardiomyocyte loss

Researchers from the group of Eva van Rooij used advanced sequencing technology to better understand the heart disease arrhythmogenic cardiomyopathy, in which heart muscle tissue is replaced by fat cells. Using explanted human hearts, they found regions in which heart muscle was actively degenerated and identified a new gene, ZBTB11, that drives heart muscle cell degradation. The results were published in Cardiovascular Research on 17 May 2022.

25 May 2022

Ohio University to launch a summer program focused on diabetes research for undergraduate students

A summer program for undergraduate students who plan to pursue a graduate or medical degree related to diabetes research will be launched at Ohio University in 2023 thanks to support from a prestigious National Institutes of Health Research Education Program (R25) grant.

24 May 2022

Study sheds light on the molecular biology behind genetic epilepsy

Sometimes, even the alteration of a single nucleotide in a gene can cause serious disease. In a young boy with epilepsy, this kind of mutation has not just affected the functioning of the protein in question – it could also curb the functioning of several closely related proteins.

23 May 2022

Molecular Biology News and Research

Further Reading

New machine learning algorithm finds a gene signature characteristic of tumors

Proteomic analysis of 2002 tumors reveals 11 distinct pan-cancer molecular subtypes

Creating CAR T cells without an immune brake

Artificial intelligence-based computational program predicts the 3D structure of rotavirus spike protein

Researchers create first comprehensive functional map of genes expressed in human cells

Metrion Biosciences appoints Dr Benedetta Montagnini as Head of European Business Development

Pulmonary and primary care experts aim to reduce the time to diagnose interstitial lung diseases

New therapeutic avoids major allergic reactions while maintaining therapeutic activity

Irregularities in production of brain cells may lead to autism spectrum disorder, finds study

Phase separation discovery could lead to new interventions to regulate immune activity

MIT researchers identify components of mucus that can inhibit fungal infections

Neuroscientists study the formation of fear memories in the brain's emotional hub

Study finds a link between aging and cancer metastases

New findings reveal potential mechanisms for cellular defects in human laminopathies

Study highlights the positive effects of Humanin G in reducing inflammation in AMD

Understanding transposons provides a new starting point to generate more powerful gene editing tools

Dr. Paul Brooks is CN Bio's New Chief Business Officer

Study unveils the novel driver of cardiomyocyte loss

Ohio University to launch a summer program focused on diabetes research for undergraduate students

Study sheds light on the molecular biology behind genetic epilepsy

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