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Novel lipid nanoparticles enhance tissue-specific drug delivery

Penn Engineers have discovered a novel means of directing lipid nanoparticles (LNPs), the revolutionary molecules that delivered the COVID-19 vaccines, to target specific tissues, presaging a new era in personalized medicine and gene therapy.

1 Oct 2024

Deep brain stimulation shows promise for improving arm and hand function after injury

Deep brain stimulation may provide immediate improvement in arm and hand strength and function weakened by traumatic brain injury or stroke, University of Pittsburgh School of Medicine researchers report today in Nature Communications.

1 Oct 2024

New mechanism uncovered behind immune decline after tuberculosis treatment

Researchers at Baylor College of Medicine and collaborating institutions have discovered a mechanism that drives the long-term decline in immune response that is observed after tuberculosis (TB) has been successfully treated.

1 Oct 2024

Researchers question the use of "cancer" for certain prostate conditions

A new paper in the Journal of the National Cancer Institute, published by Oxford University Press, indicates that patients may benefit if doctors stop calling certain early-stage changes to the prostate "cancer" at all.

1 Oct 2024

Study highlights negative consequences of exclusionary discipline

Suspending or expelling a student is one of the most severe punishments a school can impose on a student – and it can have lifelong, devastating consequences. In an updated policy statement, the American Academy of Pediatrics recommends a trauma-informed approach to supporting students and reducing the need for exclusionary discipline.

1 Oct 2024

COVID-19 vaccine uptake among pregnant women higher than expected

A study of more than 28,000 pregnancies from 2022 has found that the majority of pregnant people received the COVID-19 vaccine during its initial release.

1 Oct 2024

AAP publishes first clinical guideline for opioid use in pediatric care

The American Academy of Pediatrics has published its first clinical guideline for pediatricians on prescribing opioids, including explicit instructions on how and when to prescribe these medications for pain while reducing the long-term risk of addiction.

30 Sep 2024

UCLA Health researchers showcase advances in radiation oncology at ASTRO

UCLA Health Jonsson Comprehensive Cancer Center researchers and physicians who specialize in treating patients with radiation therapies will present data on the latest radiation oncology research and clinical trial results at the 66th annual American Society for Radiation Oncology (ASTRO) meeting in Washington D.C., Sept. 29 to Oct. 2.

27 Sep 2024

Superabsorbent polymer beads linked to increasing cases of bowel obstruction in children

Water-absorbing beads have become increasingly hazardous to children over the past 10 years, as children who swallow the beads can experience life-threatening problems such as bowel obstruction.

27 Sep 2024

Study highlights inequities in emergency care for unintentional ingestions in children

Unintentional injuries like falls, drownings and poisonings are the leading cause of death in patients ages 1-4, and a significant portion of these deaths are linked to unintentional ingestions - such as swallowing a drug or poison.

27 Sep 2024

Children with disabilities in foster care face increased risks

Children with disabilities in foster care are extremely vulnerable, facing risks of maltreatment and removal from their homes and greater need for healthcare services.

27 Sep 2024

Exclusive breastfeeding linked to lower asthma risk in infants

Infants who were exclusively fed breast milk during their hospitalization at birth were 22% less likely to develop asthma in early childhood, according to research presented during the American Academy of Pediatrics 2024 National Conference & Exhibition in Orlando.

27 Sep 2024

Vance rewrites history about Trump and Obamacare

Sen. JD Vance (R-Ohio) on Sept. 15 told viewers of NBC's "Meet the Press" that former President Donald Trump built up the Affordable Care Act, even though Trump could have chosen to do the opposite.

24 Sep 2024

Study highlights urgent need for improved care for schizophrenia

New research finds that adults with schizophrenia spectrum disorders have high rates of comorbid mental and substance use disorders and significant social and economic disadvantages, and only 26% received minimally adequate treatment.

23 Sep 2024

Alarming increase in suicidality among Black youth revealed

Traditionally, Black Americans have faced a significantly lower risk of suicide compared to their white counterparts.

19 Sep 2024

No one wants to talk about racial trauma. Why my family broke our silence.

I wasn't sure if visiting a cotton field was a good idea. Almost everyone in my family was antsy when we pulled up to the sea of white.

13 Sep 2024

Fearing the worst, schools deploy armed police to thwart gun violence

A false alarm that a gunman was roaming one Catholic high school and then another in March 2023 touched off frightening evacuations and a robust police response in the city. It also prompted the diocese to rethink what constitutes a model learning environment.

11 Sep 2024

Advanced imaging techniques offer insights into brain microstructure and disease detection

In a new study, researchers compared the orientations of nerve fibers in a human brainstem using two advanced imaging techniques: diffusion magnetic resonance imaging (dMRI)-based tractography and polarization sensitive optical coherence tomography (PS-OCT).

6 Sep 2024

Weight-loss surgery offers better control of high blood pressure compared to medications

People with obesity who underwent weight-loss surgery were more likely to control their high blood pressure over a 1-to-5 year follow-period compared to those who managed their high blood pressure with medications and lifestyle management, according to preliminary research to be presented at the American Heart Association's Hypertension Scientific Sessions 2024.

5 Sep 2024

Alirocumab reduces dangerous coronary plaque and stabilizes high-risk lesions

Intensive LDL-C lowering with alirocumab significantly reduces high-risk coronary plaque burden, transforming unstable plaques into more stable phenotypes. This lesion-level analysis underscores the enhanced efficacy compared to vessel-level approaches.

4 Sep 2024