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Breakthrough antibiotic targets gum disease without harming microbiome

The ADA Forsyth Institute, a leading oral health research organization, and Flightpath Biosciences Inc. are excited to announce a groundbreaking discovery in the fight against severe gum disease and related systemic conditions.

4 Sep 2024

Rising popularity of nicotine pouches among youth raises concerns

About half of adults can identify cigarettes and e-cigarettes, but just one in four would recognize oral nicotine pouches, and these easily available products are growing increasingly popular among teens and young adults, according to a recent study commissioned by The Ohio State University Comprehensive Cancer Center – Arthur G. James Hospital and Richard J. Solove Research Institute (OSUCCC – James).

4 Sep 2024

Avadel Pharmaceuticals announces publication of RESTORE data highlighting challenges with twice-nightly oxybates and strong patient preference for once-nightly LUMRYZ™ dosing (sodium oxybate) extended-release oral suspension (CIII)

Avadel Pharmaceuticals plc, a biopharmaceutical company focused on transforming medicines to transform lives, today announced the publication of final data from the RESTORE open-label/switch study, demonstrating that people with narcolepsy prefer once-at-bedtime LUMRYZ versus a twice-nightly immediate-release oxybate treatment option.

From Avadel Pharmaceuticals 4 Sep 2024

Wearable heart monitor for AF screening increases diagnoses but not stroke prevention

Screening for atrial fibrillation (AF) using a wearable heart monitor for 2 weeks can identify older adults with this potentially dangerous abnormal heart rhythm, but does not prevent subsequent strokes, according to late breaking research presented in a Hot Line Session at this year's ESC Congress 2024 in London, UK (30 Aug - 2 Sept).

2 Sep 2024

Mass screening for atrial fibrillation with ECG and biomarker fails to prevent stroke in older adults

Mass screening for atrial fibrillation using ECG together with heart failure biomarker does not prevent ischaemic stroke or systemic embolism (blood clot) in older adults aged 75-76 years over 5 years follow-up, according to late breaking research presented in a Hot Line Session at this year's ESC Congress 2024 in London, UK (30 Aug - 2 Sept).

2 Sep 2024

Fermented lingonberry juice shown to reduce inflammation and support gut health in IBD

Fermented lingonberry juice may help manage inflammatory bowel disease (IBD) by modulating both the oral and gut microbiomes, reducing inflammation, and promoting beneficial bacteria.

2 Sep 2024

Study finds wearable monitors effective in diagnosing atrial fibrillation

Wearable, long-term continuous heart monitors helped identify 52% more cases of atrial fibrillation compared to usual care, but that did not lead to a reduction in hospitalizations due to stroke, according to a study led by the Duke Clinical Research Institute.

1 Sep 2024

Edoxaban monotherapy superior to dual therapy in patients with high-risk AF and stable CAD

Edoxaban monotherapy reduced net adverse clinical events compared with edoxaban plus a single antiplatelet agent, when used as long-term antithrombotic therapy, in patients with high-risk atrial fibrillation (AF) and stable coronary artery disease (CAD), according to late-breaking research presented in a Hot Line session today at ESC Congress 2024.

1 Sep 2024

OCEANIC-AF trial reveals inferiority of asundexian to apixaban for stroke prevention

Asundexian 50 mg daily was inferior to apixaban for stroke and systemic embolism prevention in high-risk patients with atrial fibrillation (AF), according to late-breaking research presented in a Hot Line session today at ESC Congress 2024.

1 Sep 2024

Study finds no added benefit to routine potassium supplementation after CABG

For the prevention of new-onset atrial fibrillation (AF) after isolated coronary artery bypass graft (CABG) surgery, giving potassium supplements only when levels dropped below the lower limit of normal was non-inferior to routinely supplementing potassium to the upper limit of normal, according to late-breaking research presented in a Hot Line session today at ESC Congress 2024.

1 Sep 2024

TAVI patients show no benefit from continuing oral anticoagulants

There was no apparent benefit to continuing oral anticoagulants compared with interruption in patients undergoing transcatheter aortic valve implantation (TAVI), according to late-breaking research presented in a Hot Line session today at ESC Congress 2024.

1 Sep 2024

Major surgery complications unaffected by use of renin-angiotensin system inhibitors

There was no difference in major post-operative complications in patients who continued vs. stopped renin-angiotensin system inhibitors (RASIs) before non-cardiac surgery, according to late-breaking research presented in a Hot Line session today at ESC Congress 2024.

30 Aug 2024

New method emulates clinical trial to compare blood thinners for atrial fibrillation

Researchers used real-world clinical data to attempt to emulate a randomized controlled trial testing the effectiveness of two blood thinners, apixaban and warfarin, to prevent stroke in patients with non-valvular atrial fibrillation.

29 Aug 2024

Study shows benefits of taking misoprostol at home during medical abortions after 12 weeks

Pregnant people who took the first dose of misoprostol (a pill given as part of the procedure for medical abortions) at home had a 71% chance of completing their care in hospital within 9 hours with no overnight stay when having an abortion after 12 weeks of pregnancy, compared to 46% of those who took the first dose of misoprostol at hospital, finds a randomized controlled trial published in The Lancet.

29 Aug 2024

Oral News and Research

Breakthrough antibiotic targets gum disease without harming microbiome

Rising popularity of nicotine pouches among youth raises concerns

Avadel Pharmaceuticals announces publication of RESTORE data highlighting challenges with twice-nightly oxybates and strong patient preference for once-nightly LUMRYZ™ dosing (sodium oxybate) extended-release oral suspension (CIII)

Wearable heart monitor for AF screening increases diagnoses but not stroke prevention

Mass screening for atrial fibrillation with ECG and biomarker fails to prevent stroke in older adults

Fermented lingonberry juice shown to reduce inflammation and support gut health in IBD

Study finds wearable monitors effective in diagnosing atrial fibrillation

Edoxaban monotherapy superior to dual therapy in patients with high-risk AF and stable CAD

OCEANIC-AF trial reveals inferiority of asundexian to apixaban for stroke prevention

Study finds no added benefit to routine potassium supplementation after CABG

TAVI patients show no benefit from continuing oral anticoagulants

Major surgery complications unaffected by use of renin-angiotensin system inhibitors

New method emulates clinical trial to compare blood thinners for atrial fibrillation

Study shows benefits of taking misoprostol at home during medical abortions after 12 weeks

New antibacterial compound shows promise for preventing periodontal disease

High-dose psilocybin shows promise for depression treatment

Gut microbiota plays a critical role in rotavirus vaccine efficacy

Understanding the health benefits of polyphenols through bitter taste receptors

Maternal gut bacteria linked to changes in fetal brain metabolism

Risankizumab outperforms ustekinumab in treating moderate-to-severe Crohn’s disease

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