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The effectiveness of molnupiravir and nirmatrelvir/ritonavir in reducing hospitalization and deaths in non-hospitalized COVID-19 patients

Researchers assessed the effectiveness of two orally administered antiviral medications, nirmatrelvir/ritonavir, and molnupiravir, in decreasing hospitalization and deaths among real-world non-hospitalized COVID-19 patients in Hong Kong.

25 May 2022

Gut microbiota linked to immunocompromised people's variable response to SARS-CoV-2 vaccination

In a recent study posted to the Research Square* preprint server, researchers assessed whether disturbances in the gut microbiota weaken the serological response to the coronavirus disease 2019 (COVID-19) vaccine in inflammatory bowel disease (IBD) patients.

25 May 2022

A study on the safety of BNT162b2 COVID vaccine in children under five

In a recent research paper posted to the medRxiv* preprint server, scientists explored the safety of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) BNT162b2 vaccine in children under five years of age.

25 May 2022

Association between reactogenicity and immunogenicity in SARS-CoV-2 mRNA-1273 vaccination

A recent study currently under review at Scientific Reports journal and posted to the Research Square* preprint server demonstrated a potential positive correlation between reactogenicity and immunogenicity of coronavirus disease 2019 (COVID-19) vaccination.

25 May 2022

Immunogenicity of BNT162b2 COVID-19 vaccine in melanoma patients receiving immunotherapy

In a recent study under review at the Scientific Reports journal and posted to the Research Square* preprint server, researchers evaluated the efficacy of messenger ribonucleic acid (mRNA)-based coronavirus disease 2019 (COVID-19) vaccine BNT162b2 in cancer patients under treatment with immune checkpoint inhibitors (ICIs).

25 May 2022

Computational modeling fine tunes RBD-1C aptamer against SARS-CoV-2 S protein

Researchers used the SARS-CoV-2 sequence against aptamers to perform the in silico selection of an aptamer against the SARS-CoV-2 S protein.

24 May 2022

Study explores the substrate selectivity of the SARS-CoV-2 replicase

Researchers explored factors affecting substrate selection by the SARS-CoV-2 replicase.

24 May 2022

Hamster contact exposure challenge model assesses protection conferred by SARS-CoV-2 vaccination or prior infection against reinfection

Researchers assessed the neutralization efficacy of a saRNA vaccine targeting SARS-CoV-2 S protein against reinfection among hamsters with prior vaccination or infection.

24 May 2022

Characterizing spillover dynamics and global transmission patterns of avian influenza A viruses

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24 May 2022

Findings from the CoVaccS study on parental intention to vaccinate children against COVID

In the current preprint posted to the medRxiv* server, the researchers looked at UK parental intention to vaccinate their children during a time of selective pediatric vaccination.

24 May 2022

Vaccinated individuals with SARS-CoV-2 infection develop virus-specific T cells inside their noses

In a recent study posted to the medRxiv* preprint server, investigators in Singapore showed that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) breakthrough infection elicited broadly specific virus-selective nasal resident CD8 and CD4 T cells.

24 May 2022

Omicron vaccine breakthrough infections induce potent cross-reactive antibodies

In a recent study published in the journal Cell, researchers demonstrated that antibodies generated due to breakthrough infection (BTI) by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) new variant of concern (VOC) Omicron in vaccinated individuals could neutralize all VOCs.

24 May 2022

BNT162b2 vaccine induces robust SARS-CoV-2 immunity in children

In a recent study posted to the medRxiv* pre-print server, researchers evaluated coronavirus disease 2019 (COVID-19) vaccine-induced humoral immune response in five to 11-year-old children.

23 May 2022

Anti-SARS-CoV-2 antibodies persist in breast milk, even after gastrointestinal digestion

Researchers evaluate the persistence of anti-SARS-CoV-2 IgA and IgG in breast milk before and after in vitro gastrointestinal digestion.

23 May 2022

SARS-CoV-2 mRNA vaccines do not stimulate interferon stimulatory gene expression in Aicardi Goutières Syndrome patients

A new study aimed to evaluate the immunostimulatory potential of mRNA vaccines in AGS patients.

23 May 2022

Study reports SARS-CoV-2 accessory proteins downregulate MHC-I expression using distinct mechanisms

Researchers observed SARS-CoV-2 downregulates the expression of MHC class I molecules.

23 May 2022

Real-world vaccine effectiveness of mRNA-1273 and BNT1262b2 in immunocompromised adults

Researchers assessed the efficacy of COVID-19 vaccines in immunocompromised adults.

23 May 2022

Repurposed drug clofoctol blocks SARS-CoV-2 replication in mouse study

A new paper presents the results of a mouse study using the repurposed antibacterial drug clofoctol against this virus.

23 May 2022

Pfizer COVID-19 vaccine-associated tinnitus responds to transcranial magnetic stimulation

Pfizer-BioNTech COVID-19 vaccine-associated tinnitus was relieved with a brief course of Transcranial Magnetic Stimulation treatment.

23 May 2022

Largest study to date on the effect of vaccination on long-COVID

In a recent study published in the British Medical Journal, researchers evaluated the association between coronavirus disease 2019 (COVID-19) vaccination and long COVID symptoms among adults residing in United Kingdom (UK) communities with positive COVID-19 history before vaccination.

23 May 2022

Ribonucleic Acid News and Research

The effectiveness of molnupiravir and nirmatrelvir/ritonavir in reducing hospitalization and deaths in non-hospitalized COVID-19 patients

Gut microbiota linked to immunocompromised people's variable response to SARS-CoV-2 vaccination

A study on the safety of BNT162b2 COVID vaccine in children under five

Association between reactogenicity and immunogenicity in SARS-CoV-2 mRNA-1273 vaccination

Immunogenicity of BNT162b2 COVID-19 vaccine in melanoma patients receiving immunotherapy

Computational modeling fine tunes RBD-1C aptamer against SARS-CoV-2 S protein

Study explores the substrate selectivity of the SARS-CoV-2 replicase

Hamster contact exposure challenge model assesses protection conferred by SARS-CoV-2 vaccination or prior infection against reinfection

Characterizing spillover dynamics and global transmission patterns of avian influenza A viruses

Findings from the CoVaccS study on parental intention to vaccinate children against COVID

Vaccinated individuals with SARS-CoV-2 infection develop virus-specific T cells inside their noses

Omicron vaccine breakthrough infections induce potent cross-reactive antibodies

BNT162b2 vaccine induces robust SARS-CoV-2 immunity in children

Anti-SARS-CoV-2 antibodies persist in breast milk, even after gastrointestinal digestion

SARS-CoV-2 mRNA vaccines do not stimulate interferon stimulatory gene expression in Aicardi Goutières Syndrome patients

Study reports SARS-CoV-2 accessory proteins downregulate MHC-I expression using distinct mechanisms

Real-world vaccine effectiveness of mRNA-1273 and BNT1262b2 in immunocompromised adults

Repurposed drug clofoctol blocks SARS-CoV-2 replication in mouse study

Pfizer COVID-19 vaccine-associated tinnitus responds to transcranial magnetic stimulation

Largest study to date on the effect of vaccination on long-COVID

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