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Exploring how stress might be communicated to other animals

Heat-stressed fish embryos release chemical signals that change the appearance, behavior, and development of fish embryos that were not heat stressed, according to a study.

24 May 2023

Mays Cancer Center conducts clinical trial combining two drugs in patients with recurrent, high-grade glioblastoma

The Mays Cancer Center at The University of Texas Health Science Center at San Antonio recently conducted a clinical trial combining two drugs in patients with recurrent, high-grade glioblastoma (GBM).

24 May 2023

Scientists study the structure and function of a transporter involved in cancer, immunity

Scientists at St. Jude Children's Research Hospital and the University of Texas Southwestern Medical Center studied the structure and function of a transporter involved in cancer and immunity.

24 May 2023

Study characterizes how the inflammatory microenvironment of adult mouse prostate changes during aging

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 9, entitled, "Highly multiplexed immune profiling throughout adulthood reveals kinetics of lymphocyte infiltration in the aging mouse prostate."

24 May 2023

bit.bio launches new custom disease model cells offering, advancing disease research & drug discovery

Researchers can now order their mutation of choice in bit.bio’s opti-oxTM powered human-iPSC derived cells, receiving consistent, defined, cryopreserved products that can be immediately incorporated into drug discovery workflows.

From bit.bio 24 May 2023

The adaptive immunity of human endemic viruses

Researchers studied the evolution of the ability of viruses to evade the neutralizing antibodies.

24 May 2023

Investigating the interplay between white blood cell count and incidence of hyper-low-density lipoprotein cholesterolemia

Researchers investigating the association between white blood cell count and LDL hypercholesteremia.

24 May 2023

National-level comprehensive mapping of high-fatality SARS-CoV-2 outbreaks in nursing homes

Researchers analyzed data from three SARS-CoV-2 outbreaks among nursing homes in Belgium.

24 May 2023

New tests based on biomarkers may improve diagnosis and treatment of acute kidney injury

Hospital inpatients who develop an acute kidney injury (AKI) generally fare poorly after being discharged, and have few options for effective treatment.

24 May 2023

Unraveling the Epstein-Barr virus enigma: The puzzling role in multiple sclerosis development

Epstein-Barr virus (EBV) has a significant role in the development of multiple sclerosis (MS), with evidence linking EBV infection to increased MS risk and immune dysregulation. Understanding the mechanisms underlying this connection is crucial for advancing MS therapies and prevention strategies.

24 May 2023

Looking at cancer drugs to help put the brakes on classic indicators of aging

Antiretroviral cocktails can make human immunodeficiency virus, or HIV, undetectable and untransmittable, but both the virus and its treatment can also accelerate aging of bone and muscle.

24 May 2023

The antimicrobial potential of nanoparticles

Nanoparticles have widely been used as advanced tools for the diagnosis, prevention, and treatment of infectious diseases.

23 May 2023

Study provides data to support gene supplementation as a treatment for autosomal dominant retinitis pigmentosa

A new study shows that total RPE65 protein levels in mice with autosomal dominant retinitis pigmentosa were doubled following subretinal delivery of adeno-associated virus (AAV)-RPE65 gene supplementation.

23 May 2023

Study findings offer hope for the development of novel treatments for leishmaniasis

In an article published in the journal Nature Communications, researchers at the University of São Paulo (USP) in Brazil show how protozoans of the genus Leishmania that cause leishmaniasis manipulate a protein that plays an essential role in the organism's defense in order to continue to replicate, preventing the body from vanquishing the disease.

23 May 2023

GPR141 drives breast tumorigenesis by inducing tumor cell properties via the p-mTOR1/p53 axis

A new research paper was published in Oncotarget's Volume 14 on May 19, 2023, entitled, "G-protein-coupled receptor 141 mediates breast cancer proliferation and metastasis by regulating oncogenic mediators and the p-mTOR/p53 axis."

23 May 2023

39th Barcelona BioMed Conference focuses on latest advances in proximity induction-based pharmacology

Targeted protein degradation uses different types of "degrading" drugs (degraders) to force proximity between a target protein (for example, a mutated protein that contributes to the development of a disease) and the cellular machinery that directs protein degradation.

23 May 2023

He returned to the US for his daughter’s wedding. He left with a $42,000 hospital bill.

Last June, Jay Comfort flew to the United States from his home in Switzerland to attend his only daughter's wedding. But the week before the ceremony — on a Friday evening — Comfort said he found himself in "excruciating pain."

23 May 2023

$11.6 million NIDA grant supports the study of cannabis effects on HIV-infected brains

Weill Cornell Medicine has been awarded a five-year, $11.6 million grant from the National Institute on Drug Abuse of the National Institutes of Health to study the effects cannabis, including marijuana and compounds derived from it, may have on the brains of those living with HIV.

23 May 2023

Scientists to discuss the latest cancer therapies, advances in PSMA PET scans and many more at ASCO

Physicians and scientists from the UCLA Jonsson Comprehensive Cancer Center will discuss the latest research and clinical trial results on combination therapies for breast cancer, a potential new treatment for patients with recurrent glioma, and advances in PSMA PET guided radiotherapy for patients with prostate cancer, among other topics, at the American Society of Clinical Oncology's annual meeting.

23 May 2023

Scientists unveil a metabolic Achilles' heel in pancreatic cancer

Research unveils the significance of uridine as a metabolic fuel in pancreatic ductal adenocarcinoma (PDA) cells under glucose-deprived conditions. Uridine utilization, mediated by uridine phosphorylase 1 (UPP1), supports redox balance, survival, and proliferation in PDA, highlighting its potential as a novel therapeutic target in the treatment of this resistant cancer.

23 May 2023

Cell News and Research

Exploring how stress might be communicated to other animals

Mays Cancer Center conducts clinical trial combining two drugs in patients with recurrent, high-grade glioblastoma

Scientists study the structure and function of a transporter involved in cancer, immunity

Study characterizes how the inflammatory microenvironment of adult mouse prostate changes during aging

bit.bio launches new custom disease model cells offering, advancing disease research & drug discovery

The adaptive immunity of human endemic viruses

Investigating the interplay between white blood cell count and incidence of hyper-low-density lipoprotein cholesterolemia

National-level comprehensive mapping of high-fatality SARS-CoV-2 outbreaks in nursing homes

New tests based on biomarkers may improve diagnosis and treatment of acute kidney injury

Unraveling the Epstein-Barr virus enigma: The puzzling role in multiple sclerosis development

Looking at cancer drugs to help put the brakes on classic indicators of aging

The antimicrobial potential of nanoparticles

Study provides data to support gene supplementation as a treatment for autosomal dominant retinitis pigmentosa

Study findings offer hope for the development of novel treatments for leishmaniasis

GPR141 drives breast tumorigenesis by inducing tumor cell properties via the p-mTOR1/p53 axis

39th Barcelona BioMed Conference focuses on latest advances in proximity induction-based pharmacology

He returned to the US for his daughter’s wedding. He left with a $42,000 hospital bill.

$11.6 million NIDA grant supports the study of cannabis effects on HIV-infected brains

Scientists to discuss the latest cancer therapies, advances in PSMA PET scans and many more at ASCO

Scientists unveil a metabolic Achilles' heel in pancreatic cancer

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