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DNA resources coupled to EMR systems hold potential as valuable tools for clinical research

A new study reveals an exciting potential benefit of the rapidly accumulating databases of health care information, the ability to make unprecedented links between genomic data and clinical medicine. The research, published by Cell Press in the April issue of the American Journal of Human Genetics, supports the idea that large scale DNA databanks linked to electronic medical record (EMR) systems provide a valuable platform for discovering, assessing and validating associations between genes and diseases.

2 Apr 2010

SwitchGear Genomics introduces GoClone miRNA research tool

SwitchGear Genomics, Inc., a leading provider of products for studying regulatory elements in the human genome, today announced the launch of a unique research tool for screening for miRNA function in living cells. The new SwitchGear GoClone™ miRNA target sets utilize experimentally-validated luciferase reporter vectors to accurately quantify human 3'UTR activity in response to a number of relevant miRNAs.

2 Apr 2010

Microbes in polluted groundwater have simple genetic structures that help them overcome environmental stress

Microorganisms can indeed live in extreme environments, but the ones that do are highly adapted to survive and little else, according to a collaboration that includes Department of Energy's Oak Ridge National Laboratory and Joint Genome Institute (JGI) and the University of Oklahoma.

2 Apr 2010

Zebra finch genetic sequence decoded: help for speech impaired round the corner say researchers

Finches have been associated with evolution since the time of Darwin. In a new development researchers have successfully decoded the compete genetic make up of the zebra finch commonly known as the "little Aussie battler" (Taeniopygia guttata).

2 Apr 2010

Invalidation of gene patents: ACMG celebrates US District Court ruling

The American College of Medical Genetics (ACMG), one of the original plaintiffs in the anti-gene-patenting lawsuit filed in 2009, celebrated the US District Court ruling yesterday that genes are "unpatentable."

2 Apr 2010

New clues into genomic complexity of Mimivirus

A study published online today in the journal Genome Research offers surprising new clues into the genomic complexity of the giant Mimivirus, the largest known virus in the world. Previous studies have shown that unlike most viruses, the Mimivirus has more genes than many bacteria and performs functions that normally occur only in cellular organisms.

2 Apr 2010

Biotech reports record financial results for 2010 first quarter

Biotech racked up impressive gains for both the month of March and the first quarter of 2010. The Burrill Biotech Select Index posted a 3.7 percent jump in value in March and an 8 percent overall gain for Q1 '10.

2 Apr 2010

Feinstein Institute scientists seek sisters for lupus study

The SisSLE (Sisters of Women with Systemic Lupus Erythematosus) research study is looking for sisters: one with a diagnosis of systemic lupus erythematosus (SLE), an autoimmune disease and one (or more) who does not have lupus.

31 Mar 2010

Plant-based system could help improve lives of hemophilic patients

Hemophilia, a disease linked with legends of European monarchs, frail heirs and one flamboyant charlatan called Rasputin, still afflicts many people today.

31 Mar 2010

BioNanomatrix awarded patent covering nanochannel arrays for high-throughput macromolecular analysis

BioNanomatrix, Inc., a developer of breakthrough single-molecule genomic analysis technology, today announced the issuance of U.S. patent 7,670,770 for nanochannel arrays that enable high-throughput macromolecular analysis. Also disclosed are methods of preparing nanochannel array chips, methods of analyzing macromolecules such as entire strands of genomic DNA, and systems for implementing these methods.

31 Mar 2010

2010 John Dystel Prize for Multiple Sclerosis Research awarded to Yale University researcher

The American Academy of Neurology is awarding the 2010 John Dystel Prize for Multiple Sclerosis Research to David A. Hafler, MD, with Yale University. Hafler will receive the award during the AAN's 62nd Annual Meeting in Toronto, held April 10 through April 17, 2010.

31 Mar 2010

CLC bio signs partnership agreement with Ion Torrent

CLC bio, the world's leading bioinformatics solution provider, today announced a partnership with Ion Torrent, a new sequencing company started by Dr. Jonathan Rothberg, the founder of 454 Life Sciences. The partnership will ensure that data can directly flow off of the Ion Personal Genome Machine sequencer and into CLC bio's solutions, like CLC Genomics Workbench or CLC Genomics Server.

30 Mar 2010

New Prestige Antibodies powered by Atlas Antibodies added to Sigma Life Science's portfolio

Sigma® Life Science, the innovative biological products and services brand of Sigma-Aldrich®, today announced that it has added 2,200 new Prestige Antibodies® powered by Atlas Antibodies to its industry-leading portfolio.

From Atlas Antibodies 29 Mar 2010

New data on EHT 0202 for treatment of patients with AD presented at Geneva/Springfield Symposium

ExonHit Therapeutics announced today that promising new data on EHT 0202, its lead candidate in Alzheimer's disease, were presented at the 11th International Geneva/Springfield Symposium on Advances in Alzheimer Therapy from March 24th to March 27th in Geneva, Switzerland.

29 Mar 2010

Infrafrontier project expands to include six new partners

Helmholtz Zentrum M-nchen today announced that the Infrafrontier project, funded by the European Union, has been expanded to include six partners from Canada, the Czech Republic, Austria, France and Italy. The new partners will join the effort of the other 22 members of Infrafrontier in building up an international research infrastructure to improve open access to high-quality mouse models.

27 Mar 2010

Genome sequencing of tumors biopsied from women with invasive breast cancer

Tumors biopsied from women with invasive breast cancer are having their genomes sequenced in an attempt to develop a DNA profile that one day may identify ahead of time the patients who will most likely respond to chemotherapy with an aromatase inhibitor. Aromatase inhibitors are a class of chemotherapeutic agents that block the production of estrogen in postmenopausal women.

27 Mar 2010

Roche NimbleGen' s microarray technologies help identify genes responsible for CRC

In a recently published study in the journal Genome Research, a team of scientists led by Dr. Shaying Zhao at the University of Georgia have developed a novel cross-species comparative genomics and oncology strategy for cancer driver gene discovery, using microarray technologies from Roche NimbleGen, that differs fundamentally from current approaches which focus on human cancers only.

26 Mar 2010

FIMM to launch cell microarray screening research program utilizing Aushon 2470 Arrayer technology

Aushon BioSystems, Inc., a leading provider of advanced microarray instrumentation and laboratory services for biomarker discovery, development and analysis announced today that the Institute for Molecular Medicine Finland will launch a cell microarray screening research program utilizing the Aushon 2470 Arrayer technology.

26 Mar 2010

New experiments may hold clues for controlling cancer

A protein discovered in fruit fly eyes has brought a Johns Hopkins team closer to understanding how the human heart and other organs automatically "right size" themselves, a piece of information that may hold clues to controlling cancer.

26 Mar 2010

Interim results from ZALBIN Phase 2B trial in chronic hepatitis C patients announced

Human Genome Sciences, Inc. today announced interim results through Week 12 following the end of treatment in a Phase 2b clinical trial conducted by Novartis to evaluate the safety and efficacy of ZALBIN™ (albinterferon alfa-2b), an investigational agent, administered monthly in combination with ribavirin in 391 treatment-naive patients with genotypes 2 and 3 chronic hepatitis C virus. The primary efficacy endpoint is sustained virologic response (SVR) at Week 48 (24 weeks following the end of treatment).

26 Mar 2010

Genome News and Research

DNA resources coupled to EMR systems hold potential as valuable tools for clinical research

SwitchGear Genomics introduces GoClone miRNA research tool

Microbes in polluted groundwater have simple genetic structures that help them overcome environmental stress

Zebra finch genetic sequence decoded: help for speech impaired round the corner say researchers

Invalidation of gene patents: ACMG celebrates US District Court ruling

New clues into genomic complexity of Mimivirus

Biotech reports record financial results for 2010 first quarter

Feinstein Institute scientists seek sisters for lupus study

Plant-based system could help improve lives of hemophilic patients

BioNanomatrix awarded patent covering nanochannel arrays for high-throughput macromolecular analysis

2010 John Dystel Prize for Multiple Sclerosis Research awarded to Yale University researcher

CLC bio signs partnership agreement with Ion Torrent

New Prestige Antibodies powered by Atlas Antibodies added to Sigma Life Science's portfolio

New data on EHT 0202 for treatment of patients with AD presented at Geneva/Springfield Symposium

Infrafrontier project expands to include six new partners

Genome sequencing of tumors biopsied from women with invasive breast cancer

Roche NimbleGen' s microarray technologies help identify genes responsible for CRC

FIMM to launch cell microarray screening research program utilizing Aushon 2470 Arrayer technology

New experiments may hold clues for controlling cancer

Interim results from ZALBIN Phase 2B trial in chronic hepatitis C patients announced

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