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CHLA cardiologists perform rare fetal cardiac intervention procedure

Last August, when Children's Hospital Los Angeles cardiologists confirmed that the heart of a 27-week-old fetus suffered from a critical cardiac condition that prevented blood returning from the fetus's lungs from circulating back into the body, they told the parents that their child faced certain open-heart surgery after birth. Even worse, babies born with this very rare condition—hypoplastic left heart syndrome (HLHS) with restrictive atrial septum—have a 50 percent neonatal mortality rate.

27 Feb 2016

Discovery could lead to better therapies for people with obsessive compulsive disorder

Research led by investigators in veterinary and human medicine has identified genetic pathways that exacerbate severity of canine compulsive disorder in Doberman pinschers, a discovery that could lead to better therapies for obsessive compulsive disorder in people.

27 Feb 2016

New 3-D microscope allows researchers to look at living cancer cells in controlled microenvironment

UT Southwestern Medical Center researchers have designed and built a microscope capable of creating high-resolution, 3-D images of living cancer cells in realistic, controllable microenvironments.

27 Feb 2016

New imaging study shows how exercise affects the brain

People who exercise have better mental fitness, and a new imaging study from UC Davis Health System shows why. Intense exercise increases levels of two common neurotransmitters -- glutamate and gamma-aminobutyric acid, or GABA -- that are responsible for chemical messaging within the brain.

27 Feb 2016

Researchers develop effective technique for studying high-arched palate using mouse model

Researchers from the laboratory of Paul Trainor, Ph.D., at the Stowers Institute of Medical Research have developed an effective and reliable technique for studying high-arched palate using a mouse model. The methodology could expand research into the genetic aspects of this craniofacial abnormality.

27 Feb 2016

3D planning and CAD/CAM techniques have potential for advances in plastic and reconstructive surgery

While used mainly in craniofacial reconstruction so far, 3D planning and CAD/CAM techniques have the potential for advances in practically every area of plastic and reconstructive surgery, according to the review by Drs. Miles J. Pfaff and Derek Steinbacher of Yale University.

27 Feb 2016

New analytical tool may help diagnose cancer faster than conventional methods

Researchers have developed a new analytical tool for medical applications and biological research that might be used to diagnose cancer more rapidly than conventional methods.

26 Feb 2016

Neurosurgeons use laser probe to deliver chemotherapy drugs to patients with glioblastoma

Using a laser probe, neurosurgeons at Washington University School of Medicine in St. Louis have opened the brain's protective cover, enabling them to deliver chemotherapy drugs to patients with a form of deadly brain cancer.

26 Feb 2016

Study provides pathways to understand complex neurological disorders

Scientists have now described the engineering of a bright red fluorescent protein-based voltage indicator, providing pathways to understanding complex neurological disorders. Designated as FlicR1 (fluorescent indicator for voltage imaging red), these indicators enable imaging of the electrical activity of many genetically targeted neurons with high spatial and temporal resolution.

25 Feb 2016

Research: Impaired immune response significantly involved in rare autoimmune diseases

In the context of the multicentre EU project "INTRICATE" under the management of Renate Kain of the Clinical Institute for Pathology of MedUni Vienna, the effects of infections on the generation of rare autoimmune diseases such as granulomatous polyangiitis (GPA), a systemic disease of the vascular system, are examined.

25 Feb 2016

Frontotemporal dementia often misdiagnosed as Alzheimer’s disease in many patients

Many patients showing signs of dementia are quickly diagnosed with Alzheimer's disease when they might actually suffer from frontotemporal dementia, delaying the appropriate treatment for them.

25 Feb 2016

Active mind may delay symptoms of Alzheimer's disease, but not underlying brain changes

Keeping the mind active may delay symptoms of Alzheimer's disease; however, the activity does not change the underlying disease in the brain for most people, according to a study published today in the online edition of Neurology, the medical journal of the American Academy of Neurology.

25 Feb 2016

Gene expression analysis points metastatic CRC patient to successful irbesartan therapy

A patient with recurrent metastatic colorectal cancer has been successfully treated with the angiotensin receptor blocker irbesartan, researchers report.

24 Feb 2016

Does simulated based training bring better value healthcare? An interview with Prof Sir Muir Gray, Former Chief Knowledge Officer of the NHS

We have to think of the world that we are leaving, the world we are moving into. The last fifty years in healthcare, have seen the advent of hip replacement, cardiac bypass, systematic reviews. But at the end of fifty years, every country is facing five problems.

24 Feb 2016

MR Solutions introduces new 3D in vivo confocal microscope for preclinical research

MR Solutions’ new 3D in vivo confocal microscope for use in preclinical research provides a magnification range of up to 1000 times, allowing researchers to examine cellular details within a live small animal eliminating the need for a surgical biopsy - saving time and substantially reducing costs.

From MR Solutions 24 Feb 2016

ONR researcher explores how explosive shock waves contribute to traumatic brain injury

Today's warfighters are outfitted with body armor strong enough to withstand shrapnel from a bomb or other explosive device. One debilitating threat from a blast, however, is a force they can't see--the explosive shock wave itself.

24 Feb 2016

Current DRG-based cost recovery system appears problematic for patients with complex disorders

A new study by researchers from Charité - Universitätsmedizin Berlin compares the true cost of treating patients with chronic inflammatory bowel disease with costs recoverable under the current German DRG-based system.

24 Feb 2016

New TAU study suggests potential therapeutic pathway to keep osteosarcoma lesions dormant

Osteosarcoma is a cancer that develops in the bones of children and adolescents. It is one of the most aggressive cancers, with only a 15 per cent, five-year survival rate when diagnosed in an advanced metastatic stage. There are approximately 800 new cases diagnosed each year in the US, and no viable treatments.

23 Feb 2016

Boston Scientific gets FDA approval for ACUITY X4 Quadripolar Left Ventricular leads

Boston Scientific has received U.S. Food and Drug Administration approval for the ACUITY X4 Quadripolar Left Ventricular (LV) leads. The FDA approval of the quadripolar leads, the wires that connect cardiac resynchronization therapy (CRT) devices to the heart, marks the first time the company will offer a full X4 CRT system – both the device and the leads – to the U.S. market.

23 Feb 2016

Damage to language network structural hubs can affect severity of aphasia following stroke

When brain regions that control speech and reading comprehension are destroyed due to blockage of blood flow, patients are often unable to speak or comprehend spoken or written language. These difficulties with language, or "aphasia," are a common symptom in the aftermath of stroke. However, in a new study published in Restorative Neurology and Neuroscience, researchers report that damage to the underlying connections among different areas of the brain can also affect the severity of aphasia.

23 Feb 2016

Imaging News and Research

CHLA cardiologists perform rare fetal cardiac intervention procedure

Discovery could lead to better therapies for people with obsessive compulsive disorder

New 3-D microscope allows researchers to look at living cancer cells in controlled microenvironment

New imaging study shows how exercise affects the brain

Researchers develop effective technique for studying high-arched palate using mouse model

3D planning and CAD/CAM techniques have potential for advances in plastic and reconstructive surgery

New analytical tool may help diagnose cancer faster than conventional methods

Neurosurgeons use laser probe to deliver chemotherapy drugs to patients with glioblastoma

Study provides pathways to understand complex neurological disorders

Research: Impaired immune response significantly involved in rare autoimmune diseases

Frontotemporal dementia often misdiagnosed as Alzheimer’s disease in many patients

Active mind may delay symptoms of Alzheimer's disease, but not underlying brain changes

Gene expression analysis points metastatic CRC patient to successful irbesartan therapy

Does simulated based training bring better value healthcare? An interview with Prof Sir Muir Gray, Former Chief Knowledge Officer of the NHS

MR Solutions introduces new 3D in vivo confocal microscope for preclinical research

ONR researcher explores how explosive shock waves contribute to traumatic brain injury

Current DRG-based cost recovery system appears problematic for patients with complex disorders

New TAU study suggests potential therapeutic pathway to keep osteosarcoma lesions dormant

Boston Scientific gets FDA approval for ACUITY X4 Quadripolar Left Ventricular leads

Damage to language network structural hubs can affect severity of aphasia following stroke

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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