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Researchers report ‘hybrid immune damping’ following SARS-CoV-2 Omicron infection

Researchers explore the impact of differential immune imprinting patterns in individuals vaccinated against COVID-19 with a history of prior infection.

25 Jul 2022

How SARS-CoV-2 Omicron spike mutations contribute to increased infectivity

Researchers study the functional impact of Omicron mutations.

25 Jul 2022

A VSV-based COVID vaccine effective against SARS-CoV-2 variants

A new study discusses the development of recombinant vesicular stomatitis virus COVID-19 vaccines.

25 Jul 2022

How COVID-19 affects the brain microvasculature

A recent study discusses the effects of COVID-19 on the brain microvascular system.

25 Jul 2022

Why Omicron is more infectious than other SARS-CoV-2 variants

Researchers describe SARS-CoV-2 Omicron mutations and their impact on neutralization and infectivity.

25 Jul 2022

Genome arrangement of tree ferns offers insights into its evolution

Land plants evolved 470 million years ago from algae and have since reshaped our world. Throughout their evolution, ferns have undergone a series of changes that have helped them survive on land.

25 Jul 2022

Insights into molecular folding of AAT protein will help develop new therapies for alpha-1 antitrypsin deficiency

In a major new development in the quest to develop better gene therapies with which to treat a host of diseases, researchers at the University of Massachusetts Amherst and UMass Chan Medical School recently announced that they have mapped the expression and maturation of the protein alpha-1 antitrypsin (AAT) with unprecedented clarity.

25 Jul 2022

Elevated insulin resistance, advanced cell aging associated with childhood poverty

Black adolescents who lived in poverty and were less optimistic about the future showed accelerated aging in their immune cells and were more likely to have elevated insulin resistance at ages 25-29, researchers found.

25 Jul 2022

SARS-CoV-2 hijacks tiny bridges that link infected cells with neurons to gain access to brain cells

COVID-19 often leads to neurological symptoms, such as a loss of taste or smell, or cognitive impairments (including memory loss and concentration difficulties), both during the acute phase of the disease and over the long term with "long COVID" syndrome.

25 Jul 2022

Researchers investigate the feasibility of modifying cholera toxin for targeted delivery to specific organelles

Proteins usually undergo modifications during or after their synthesis in the endoplasmic reticulum (ER) and Golgi apparatus network inside eukaryotic cells.

25 Jul 2022

SARS-CoV-2 spike protein can lead to heart muscle injury through the inflammatory process

Heart damage is common among patients hospitalized with COVID-19, leading many to wonder how the virus affects the heart.

25 Jul 2022

Study provides the crucial antigenic map of SARS-CoV-2 variants of concern

Twenty different COVID-19 variants were effectively identified and neutralized after a third booster, according to the new study for which the University of Surrey provided the crucial antigenic map of variants of concern.

25 Jul 2022

Study suggests a possible treatment approach for cancer and cardiovascular disease

A key molecule for cancer metastasis has been identified as a molecule already known for its involvement in cardiovascular disease, suggesting a possible treatment approach for both diseases simultaneously.

25 Jul 2022

Study identifies risks in the use of CRISPR therapeutics

The researchers caution: "The CRISPR genome editing method is very effective, but not always safe. Sometimes cleaved chromosomes do not recover and genomic stability is compromised - which in the long run might promote cancer."

25 Jul 2022

Research reveals molecular clues associated with traumatic brain injury

New research led by scientists at Arizona State University has revealed some of the first detailed molecular clues associated with one of the leading causes of death and disability, a condition known as traumatic brain injury (TBI).

23 Jul 2022

Defect in a protein causes motor disorders in flies

Researchers at the Universities of Bonn and Osnabrück have discovered a protein whose defect causes motor disorders in flies.

22 Jul 2022

Two UTHSC research teams receive CORNET Awards for novel projects

Two research teams at the University of Tennessee Health Science Center (UTHSC) have been awarded the 2022 UTHSC Collaborative Research Network (CORNET)-Functional Genomics Award. Each team will receive $50,000 to support their novel projects.

22 Jul 2022

Study reveals new mechanism that regulates auditory sensitivity

A new study published in PNAS highlights a newly identified mechanism of how auditory sensitivity is regulated that could temporarily reduce sensitivity of the auditory system to protect itself from loud sounds that can cause irreversible damage.

22 Jul 2022

Lymphatic capillaries act as a signaling hub to control intestinal stem cell activity

To act as a robust barrier against pathogens while also absorbing needed nutrients, the lining of the intestines must regenerate on a daily basis to remain equal to the task.

22 Jul 2022

Study clarifies the role of intestinal white blood cells in colorectal cancer

Colorectal tumors are swarming with white blood cells, but whether these cells help or hinder the cancer is hotly debated.

22 Jul 2022

B Cell News and Research

Researchers report ‘hybrid immune damping’ following SARS-CoV-2 Omicron infection

How SARS-CoV-2 Omicron spike mutations contribute to increased infectivity

A VSV-based COVID vaccine effective against SARS-CoV-2 variants

How COVID-19 affects the brain microvasculature

Why Omicron is more infectious than other SARS-CoV-2 variants

Genome arrangement of tree ferns offers insights into its evolution

Insights into molecular folding of AAT protein will help develop new therapies for alpha-1 antitrypsin deficiency

Elevated insulin resistance, advanced cell aging associated with childhood poverty

SARS-CoV-2 hijacks tiny bridges that link infected cells with neurons to gain access to brain cells

Researchers investigate the feasibility of modifying cholera toxin for targeted delivery to specific organelles

SARS-CoV-2 spike protein can lead to heart muscle injury through the inflammatory process

Study provides the crucial antigenic map of SARS-CoV-2 variants of concern

Study suggests a possible treatment approach for cancer and cardiovascular disease

Study identifies risks in the use of CRISPR therapeutics

Research reveals molecular clues associated with traumatic brain injury

Defect in a protein causes motor disorders in flies

Two UTHSC research teams receive CORNET Awards for novel projects

Study reveals new mechanism that regulates auditory sensitivity

Lymphatic capillaries act as a signaling hub to control intestinal stem cell activity

Study clarifies the role of intestinal white blood cells in colorectal cancer

Industry focus eBook - Cell and gene therapy (2nd edition) eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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