B Cell News and Research

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New vaccine shows promise to fight Lassa virus

Researchers at the University of Texas Medical Branch have achieved success with a new vaccine developed to fight Lassa Virus, a pathogen that causes Lassa fever.

19 Jul 2022

COVID-19 vaccine-boosted neutralizing antibody levels decrease substantially within 3 months

Although COVID-19 booster vaccinations in adults elicit high levels of neutralizing antibodies against the Omicron variant of SARS-CoV-2, antibody levels decrease substantially within 3 months, according to new clinical trial data.

19 Jul 2022

Gut-lung axis: Using commensal bacteria to reinforce mucosal immunity

A recent study discusses the use of commensal bacteria in the gut and/or respiratory tract to deliver viral antigens to the host, thus acting as vaccines

19 Jul 2022

Discovery about how a certain protein is activated in tumor cells could lead to better treatments

Better treatments for some of cancer's deadliest forms could be closer due to a University of California, Irvine-led discovery about how a certain protein is activated in tumor cells.

19 Jul 2022

First-of-its-kind roadmap reveals how stem cells become sensory interneurons

Researchers at the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA have developed a first-of-its-kind roadmap detailing how stem cells become sensory interneurons - the cells that enable sensations like touch, pain and itch.

19 Jul 2022

Study shows how a critical Lassa virus protein drives infection

Lassa fever is a viral illness that is far too common in West Africa. Although it can have a mortality rate of 15 percent in severe cases, up to 90% in pregnant women, and causes deafness in a quarter of survivors, there is no vaccine or antiviral to protect against Lassa virus.

19 Jul 2022

Elephant genes could offer new clues to preventing cancer development

Scientists modeling the cancer-suppressing p53 gene identify how the 20 different molecules unique to elephants get activated for increased sensitivity and response against carcinogenic conditions - with implications for cancer treatments in humans.

19 Jul 2022

Gonorrhea bacteria may have driven the evolution of gene variants that protect older adults against dementia

Researchers at University of California San Diego School of Medicine previously found a set of human gene mutations that protect older adults against cognitive decline and dementia.

19 Jul 2022

Pain control method has revolutionized the experience for bone marrow donors, reduced the need for opioids

Sharing gifts is a favorite way to sustain connection across peoples and cultures worldwide, but with bone marrow donation the gift-giving act is accompanied by uncomfortable side effects to the donor, making it a truly selfless expression of kindness.

19 Jul 2022

Researchers report genomic profiling from more than 110,000 tumors

Researchers analyzed data from the latest public release of the GENIE project of the American Association for Cancer Research.

19 Jul 2022

The known and proposed interactions of SARS-CoV and SARS-CoV-2 with DNA damage response pathways

Researchers reviewed the consequences of infection with sSARS-CoVs on the host DNA damage response.

19 Jul 2022

Tissue nanotransfection technology can serve as a non-viral, topical, gene-editing delivery device, research shows

The Indiana Center for Regenerative Medicine and Engineering (ICRME) at Indiana University School of Medicine is home to tissue nanotransfection (TNT) regenerative medicine technology that achieves functional tissue reprogramming in the live body.

19 Jul 2022

Researchers use high-speed atomic force microscopy to explore the binding mechanism of cadherins

Cell, tissue, and organ structure is maintained by cell-cell adhesion molecules that connect opposing cells. Cadherins are a class of essential cell-cell adhesion molecules for tissue formation and integrity, and defects in cadherin function cause various diseases (e.g., cancer invasion).

19 Jul 2022

Six-country African study highlights the potential dangers of getting COVID-19 during pregnancy

A new study involving hospitalized women in six African countries from the University of Maryland School of Medicine's (UMSOM) Institute of Human Virology (IHV) showed that pregnant women with SARS-CoV-2, the virus that causes COVID-19, had double the risk of being admitted to the intensive care unit (ICU) and four-times the risk of dying in-hospital than pregnant women who did not have COVID-19.

19 Jul 2022

Should siRNA-based antivirals be added to the COVID toolbox?

A recent study reviewed the existing treatment modalities, including vaccines and antivirals, for SARS-CoV-2 infection.

19 Jul 2022

Researchers develop new SERS method for active capture of target molecules

Recently, a team led by Prof. Yang Liangbao from Hefei Institutes of Physical Science, Chinese Academy of Sciences used the nano-capillary pumping action to automatically capture the target molecules into a smaller gap and achieve highly sensitive Surface-Enhanced Raman Spectroscopy (SERS) detection by constructing a multilayer nanoparticle film to form a natural gap of less than 3 nm between the layers.

19 Jul 2022

Sex matters when it comes to immune responses to vaccines and viral infections

A review published in Frontiers in Aging analyzed the sex differences in the safety, effectiveness, and immunogenicity of influenza and COVID-19 vaccines in older individuals. It also analyzed the way sex brings about the modification of the impact of age-related factors on vaccination.

18 Jul 2022

Rice researchers use deactivated Cas9 proteins to synthetically trigger the transcription of genes

Rice University researchers have demonstrated that CRISPR-Cas9, increasingly famous as a gene-editing tool, can be employed in powerful additional ways in human cells.

18 Jul 2022

Researchers find link between brain protein and increased vulnerability to neurodegeneration in epilepsy patients

A team of Florida State University College of Medicine researchers has found a link between a specific protein in the brain and increased vulnerability to neurodegeneration for individuals with temporal lobe epilepsy (TLE).

18 Jul 2022

Research describes one of the ways the SARS-CoV-2 virus recruits cells to replicate

An article published in the journal Frontiers in Cellular and Infection Microbiology reports a study by researchers at the State University of Campinas (UNICAMP) and the University of São Paulo (USP) in Brazil showing how a human protein interacts with a SARS-CoV-2 protein, and describing one of the ways the virus that causes COVID-19 recruits cells to replicate.

18 Jul 2022

B Cell News and Research

New vaccine shows promise to fight Lassa virus

COVID-19 vaccine-boosted neutralizing antibody levels decrease substantially within 3 months

Gut-lung axis: Using commensal bacteria to reinforce mucosal immunity

Discovery about how a certain protein is activated in tumor cells could lead to better treatments

First-of-its-kind roadmap reveals how stem cells become sensory interneurons

Study shows how a critical Lassa virus protein drives infection

Elephant genes could offer new clues to preventing cancer development

Gonorrhea bacteria may have driven the evolution of gene variants that protect older adults against dementia

Pain control method has revolutionized the experience for bone marrow donors, reduced the need for opioids

Researchers report genomic profiling from more than 110,000 tumors

The known and proposed interactions of SARS-CoV and SARS-CoV-2 with DNA damage response pathways

Tissue nanotransfection technology can serve as a non-viral, topical, gene-editing delivery device, research shows

Researchers use high-speed atomic force microscopy to explore the binding mechanism of cadherins

Six-country African study highlights the potential dangers of getting COVID-19 during pregnancy

Should siRNA-based antivirals be added to the COVID toolbox?

Researchers develop new SERS method for active capture of target molecules

Sex matters when it comes to immune responses to vaccines and viral infections

Rice researchers use deactivated Cas9 proteins to synthetically trigger the transcription of genes

Researchers find link between brain protein and increased vulnerability to neurodegeneration in epilepsy patients

Research describes one of the ways the SARS-CoV-2 virus recruits cells to replicate

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