Liver News and Research

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Scientists invent novel low-viscosity gel for regenerating human tissue

University of Delaware scientists have invented a novel biomaterial with surprising antibacterial properties that can be injected as a low-viscosity gel into a wound where it rigidifies nearly on contact--opening the door to the possibility of delivering a targeted payload of cells and antibiotics to repair the damaged tissue.

19 Jul 2007

Plumber protein uses different tools to turn on genes

St. Jude investigators have discovered how a single molecular "on switch" triggers gene activity that might cause effects ranging from learning and memory capabilities to glucose production in the liver.

18 Jul 2007

Mathematical model identifies genes which fight viruses

Joint research by Dr. Leonid Brodsky, of the Institute of Evolution of the University of Haifa, and Dr. Milton Taylor, of Indiana University, led to the discovery of a mathematical method which can identify which genes in our bodies conduct the battle against the various viruses that attack us.

18 Jul 2007

Paracetamol for pain relief after surgical removal of lower wisdom teeth

The commonly used and inexpensive analgesic acetaminophen (Tylenol or paracetamol) is an effective pain reliever after surgical removal of lower wisdom teeth, according to a new systematic review of 21 studies.

18 Jul 2007

Correcting birth defects

Traditionally when a baby was born with a malformation of the lung or esophagus, they had to undergo open surgery involving a large chest incision with risk for serious complications.

18 Jul 2007

Insulin resistance in skeletal muscle can be countered through exercise

Abdominal fat, the spare tire that many of us carry, has long been implicated as a primary suspect in causing the metabolic syndrome, a cluster of conditions that includes the most dangerous heart attack risk factors: prediabetes, diabetes, high blood pressure, and changes in cholesterol.

17 Jul 2007

Scientists discover human genes hover between "on"and "off" in any given cell

Biologists have long thought that a simple on/off switch controls most genes in human cells.

13 Jul 2007

Contaminated toothpaste now in the UK

Contaminated toothpaste has now found it's way into the UK. Fake Sensodyne toothpaste which contains traces of toxic chemicals is being sold in markets, discount shops and car boot sales.

12 Jul 2007

First mouse model of lung transplantation

Lung transplants have been performed successfully for more than 20 years in humans but never before in mice – until now.

12 Jul 2007

New advance in search for effective treatment for human liver cancer

Researchers from the University of Pittsburgh School of Medicine report a significant new advance in the search for an effective treatment for human liver cancer in the July issue of Molecular Cancer Therapeutics.

12 Jul 2007

Researchers measure effect of hepatitis B on patients' quality of life

"Am I going to die? I have no future." "I feel depressed at times, fearful I may not see my children marry or be a grandparent." Such heart-rending statements from patients with chronic hepatitis B reveal the social and mental impact of this disease, which affects 350 million worldwide.

11 Jul 2007

Genetically engineered herpes simplex virus keeps arteries free-flowing

A genetically engineered herpes simplex virus, primarily known for causing cold sores, may help keep arteries "free-flowing" in the weeks following angioplasty or stent placement for patients, according to research published early in the online edition of PNAS (Proceedings of the National Academy of Sciences of the United States of America).

11 Jul 2007

Potential role of milk thistle as an anticancer agent

Milk thistle extract, an herbal remedy since the times of the ancient Greeks and Romans, is today one of the most popular herbal supplements, with U.S. retail sales of nearly nine million dollars.

11 Jul 2007

Adiponectin serves as energy-conserving signal to the brain

A fat-derived protein known for its effects on the liver and skeletal muscle might also serve as an energy-conserving signal to the brain during periods of starvation, suggests a new study in the July issue of Cell Metabolism, a publication of Cell Press.

11 Jul 2007

Discovery of gallstone gene

Scientists at the University of Bonn, together with colleagues from Romania, have discovered a gene variant that significantly increases the risk of developing gallstones (Hepatology No. 46, 11 July 2007, DOI 10.1002/hep.21847).

11 Jul 2007

Uncooked fish linked with liver cancer in Asia

An age old preference for eating uncooked fish dishes like koi-pla puts people in SE Asia at risk of ingesting trematodes that can cause a type of liver cancer called cholangiocarcinoma (cancer of the bile ducts), say researchers in this week's PLoS Medicine.

10 Jul 2007

Gene therapy offers promising approach to tackle pancreatic cancer

A molecularly engineered therapy selectively embeds a gene in pancreatic cancer that shrinks or eradicates tumors, inhibits metastasis, and prolongs survival with virtually no toxicity, researchers from The University of Texas M. D. Anderson Cancer Center report in the July 9 edition of Cancer Cell.

10 Jul 2007

Etravirine reduces HIV viral loads when taken with Prezista

The experimental antiretroviral drug etravirine, made by Johnson & Johnson subsidiary Tibotec Pharmaceuticals, greatly reduces HIV viral loads in people with a history of drug resistance when taken in combination with Tibotec's antiretroviral Prezista, according to two studies published Saturday in the journal The Lancet.

10 Jul 2007