Brain Tumor News and Research

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A Brain Tumor is the growth of abnormal cells in the tissues of the brain. Brain tumors can be benign (not cancer) or malignant (cancer).

New 3D endoscope at UMDNJ-The University Hospital can treat complex neurosurgical diseases

Ana Cores, a 54-year old Hackensack resident, worried about how a sudden loss of peripheral vision would impact the quality of her life. After undergoing MRIs, eye exams and many diagnostic tests, Cores opted to visit UMDNJ-The University Hospital where Dr. James K. Liu, a skull base neurosurgeon, and Dr. Jean Anderson Eloy, an otolaryngologist, used a new three- dimensional endoscope to remove a brain tumor through her nose that was pressing on her optic nerve and causing her to go blind.

20 Sep 2012

Bioengineers design nanoparticles that can safely and predictably infiltrate deep into the brain

The brain is a notoriously difficult organ to treat, but Johns Hopkins researchers report they are one step closer to having a drug-delivery system flexible enough to overcome some key challenges posed by brain cancer and perhaps other maladies affecting that organ.

12 Sep 2012

ImmunoCellular completes enrollment in ICT-107 Phase II trial for glioblastoma

ImmunoCellular Therapeutics, Ltd. announced today that the company has completed enrollment for its Phase II randomized, double-blinded, placebo-controlled, multi-center trial of its dendritic cell-based cancer vaccine ICT-107 for treatment of glioblastoma.

6 Sep 2012

Novartis receives FDA approval for Afinitor Disperz to treat subependymal giant cell astrocytoma

The U.S. Food and Drug Administration today approved Afinitor Disperz (everolimus tablets for oral suspension), a new pediatric dosage form of the anti-cancer drug Afinitor (everolimus) used to treat a rare brain tumor called subependymal giant cell astrocytoma.

30 Aug 2012

People with guanine version of rs55705857 SNP more likely to develop gliomas

People who carry a "G" instead of an "A" at a specific spot in their genetic code have roughly a six-fold higher risk of developing certain types of brain tumors, a Mayo Clinic and University of California, San Francisco study has found. The

27 Aug 2012

Pyruvate kinase M2 fuels tumor growth by influencing H3 histone protein

A metabolic protein that nourishes cancer cells also activates tumor-promoting genes by loosening part of the packaging that entwines DNA to make up chromosomes, a team led by scientists at The University of Texas MD Anderson Cancer Center reports in the Aug. 16 issue of Cell.

17 Aug 2012

Passenger deletions that deactivate essential genes provide new opportunity to strike cancer

Genomic deletions promote cancer by carving up or eliminating tumor-suppressor genes, but now scientists report in the journal Nature that the collateral damage they inflict on neighboring genes exposes cancer cells to vulnerabilities and new avenues for attack.

16 Aug 2012

Cedars-Sinai's ICT-107 doubles median survival of patients with malignant brain tumor

An experimental immune-based therapy more than doubled median survival of patients diagnosed with the most aggressive malignant brain tumor, Cedars-Sinai Medical Center researchers reported in Cancer Immunology, Immunotherapy, published online Aug. 3.

16 Aug 2012

Allergies appear to lower brain tumor risk

Testing positive for immunoglobulin E, a biomarker of allergy, reduces a person’s risk for developing glioma, show study findings.

10 Aug 2012

Work solvent-related brain tumor concerns allayed

There is no consistent evidence for increased risk for glioma or meningioma following occupational exposure to chlorinated solvents, say researchers.

8 Aug 2012

Clinical trial targets breast cancer cells by injecting trastuzumab directly into the spinal fluid

In two to five percent of women with breast cancer, tumor cells migrate into the spinal fluid invading the tissue surrounding the brain and spinal cord called the meninges. While a rare complication, the condition is challenging because there is no agreed-upon standard of treatment, leaving little hope for patients affected. Northwestern Medicine- researchers are currently examining a novel approach to delivering an FDA approved drug that they hope will advance research for this type of cancer and lead to discoveries that may improve outcomes in the future.

7 Aug 2012

Allergies may reduce risk of brain cancer

New research adds to the growing body of evidence suggesting that there's a link between allergies and reduced risk of a serious type of cancer that starts in the brain. This study suggests the reduced risk is stronger among women than men, although men with certain allergy profiles also have a lower tumor risk.

3 Aug 2012

New insight into why glioblastoma multiforme recurs in adults

A study by UT Southwestern Medical Center researchers published online today in Nature reveals new insight into why the most common, deadly kind of brain tumor in adults recurs and identifies a potential target for future therapies.

2 Aug 2012

Fusion of FGFR and TACC gene leads to glioblastoma

Researchers at Columbia University Medical Center (CUMC) have discovered that some cases of glioblastoma, the most common and aggressive form of primary brain cancer, are caused by the fusion of two adjacent genes.

26 Jul 2012

NBTI participates in ICT-107 phase II trial for glioblastoma multiforme

Researchers at Northwestern Brain Tumor Institute (NBTI) are seeking to understand if a vaccine made from a patient's own blood cells may slow the growth of a type of brain tumor.

25 Jul 2012

New tool uses fluorescence to distinguish cancerous tissue from normal one in low-grade tumors

A new probe developed collaboratively at Norris Cotton Cancer Center and Dartmouth College's Thayer School of Engineering uses an innovative fluorescence-reading technology to help brain surgeons distinguish cancerous tissue from normal tissue. The probe tool, now already in use at the Cancer Center for brain surgery, may one day be used for surgeries for a variety of cancers.

25 Jul 2012

Neural precursor cells suppress aggressive tumors

Neural precursor cells (NPC) in the young brain suppress certain brain tumors such as high-grade gliomas, especially glioblastoma (GBM), which are among the most common and most aggressive tumors.

23 Jul 2012

Researchers identify several gene mutations responsible for medulloblastoma

Researchers at the Stanford University School of Medicine and Lucile Packard Children's Hospital have identified several gene mutations responsible for the most common childhood brain tumor, called medulloblastoma, adding evidence to the theory that the diagnosis is a group of genetically distinct cancers with different prognoses. These and accompanying findings are likely to lead to less-toxic, better-targeted treatment approaches over the next two years, the researchers said.

23 Jul 2012

Researchers link specific gene mutations with four recognized subtypes of medulloblastoma

Researchers at Dana-Farber/Children's Hospital Cancer Center (DF/CHCC) and several collaborating institutions have linked mutations in specific genes to each of the four recognized subtypes of medulloblastoma, the most common malignant brain tumor of children. The discovery, reported July in the journal Nature, provides doctors with potential biomarkers for guiding and individualizing treatment and reveals prospective therapeutic opportunities for countering this devastating malignancy.

23 Jul 2012

Study confirms a rare susceptibility variant in glioma

Researchers at Moffitt Cancer Center working with colleagues at three other institutions have validated a link between a rare genetic variant and the risk of glioma, the most common and lethal type of brain tumor.

3 Jul 2012

Brain Tumor News and Research

Further Reading

New 3D endoscope at UMDNJ-The University Hospital can treat complex neurosurgical diseases

Bioengineers design nanoparticles that can safely and predictably infiltrate deep into the brain

ImmunoCellular completes enrollment in ICT-107 Phase II trial for glioblastoma

Novartis receives FDA approval for Afinitor Disperz to treat subependymal giant cell astrocytoma

People with guanine version of rs55705857 SNP more likely to develop gliomas

Pyruvate kinase M2 fuels tumor growth by influencing H3 histone protein

Passenger deletions that deactivate essential genes provide new opportunity to strike cancer

Cedars-Sinai's ICT-107 doubles median survival of patients with malignant brain tumor

Allergies appear to lower brain tumor risk

Work solvent-related brain tumor concerns allayed

Clinical trial targets breast cancer cells by injecting trastuzumab directly into the spinal fluid

Allergies may reduce risk of brain cancer

New insight into why glioblastoma multiforme recurs in adults

Fusion of FGFR and TACC gene leads to glioblastoma

NBTI participates in ICT-107 phase II trial for glioblastoma multiforme

New tool uses fluorescence to distinguish cancerous tissue from normal one in low-grade tumors

Neural precursor cells suppress aggressive tumors

Researchers identify several gene mutations responsible for medulloblastoma

Researchers link specific gene mutations with four recognized subtypes of medulloblastoma

Study confirms a rare susceptibility variant in glioma

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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