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Protein plays important roles in intracellular membrane trafficking in the brain

Our bodies couldn’t operate without the central nervous system - a complex network that coordinates our actions, reflexes, and sensations. Each neuron in your brain has one long cable that snakes away from the main part of the cell.

20 Aug 2019

Loss of cells in the brain found to be associated with stuttering

Researchers believe that stuttering - a potentially lifelong and debilitating speech disorder - stems from problems with the circuits in the brain that control speech, but precisely how and where these problems occur is unknown.

19 Aug 2019

Chlamydia vaccine shows promise after a successful clinical trial

A vaccine against the sexually transmitted infection (STI) chlamydia is now a substantial step closer to reality after successfully passing its Phase 1 clinical trial.

14 Aug 2019

Discovery of molecular mechanism behind spread of leishmania infection

Researchers from the Institut National de la Recherche Scientifique (INRS) have made a breakthrough in understanding the reason behind the virulence of leishmania parasite. The leishmania parasite is responsible for causing leishmaniasis which affects over 12 million people across the globe and is a chronic parasitic disease.

14 Aug 2019

Researchers identify new transmembrane protein as chloride ion channel

In the human body the salt content of cells and their surrounding is regulated by sophisticated transport systems.

14 Aug 2019

Researchers make scientific breakthrough regarding Leishmania virulence strategy

A team from the Institut National de la Recherche Scientifique has made a scientific breakthrough regarding the virulence strategy employed by the Leishmania parasite to infect cells of the immune system.

12 Aug 2019

Research offers new clues into why cognitive functions become impaired with age

Research at the University of Leicester is offering new clues into how and why cognitive functions such as memory and learning become impaired with age. A paper published recently in a specialist neuroscience journal shows that a crucial factor is calcium levels in specific cells in the brain.

9 Aug 2019

Novel therapeutic strategy for treating Lafora Disease shows promise in preclinical study

A team of scientists have designed and tested in mice a novel and promising therapeutic strategy for treating Lafora Disease, a fatal form of childhood epilepsy.

25 Jul 2019

Common feature that makes cancer cells appear bloated could be their potential weak spot

In a study using yeast cells and data from cancer cell lines, Johns Hopkins University scientists report they have found a potential weak spot among cancer cells that have extra sets of chromosomes, the structures that carry genetic material.

23 Jul 2019

Aging nerve cells fail to take out the intracellular "trash"

Researchers at the Perelman School of Medicine at the University of Pennsylvania, have found that with age the neurons or nerve cells fail to perform an activity that they could when they were younger. The team explains that normal cells take out protein and other “trash” or “garbage” through a process of autophagy. This rids the cell of the dysfunctional proteins and aggregates of unused proteins.

22 Jul 2019

New insights into molecular motors could help treat neurological disorders

Nerve cells form the basis of the nervous system in animals, as they transfer information between the various sensory and effector organs of the body and the brain and spinal cord. However, this function relies heavily on the transport of several proteins and other molecules between various parts of the cell.

15 Jul 2019

New study reveals 'clutch' proteins responsible for putting T cell activation 'into gear'

In collaborative research, scientists from three continents were able to discover a crucial bit of information about how T cells move proteins inside them to drive the immune response. This could help evolve specific new treatments centered on T cell selectivity.

12 Jul 2019

Study sheds light on complex caspase-1-induced cell death mechanisms

Most unnecessary or dangerous cells such as virus-infected cells commit suicide by activating an in-built suicide program.

5 Jul 2019

Researchers identify molecular pathway underpinning exercise and improved motor learning

Muscle memory -- it's not just a saying. Repetitive exercise induces improved learning for motor skills, and researchers have now identified the molecular pathway underpinning the process.

4 Jul 2019

Using NMR to Study Protein Structure, Dynamics and Mechanisms

Fábio Almeida describes how NMR can be used to elucidate protein structure and how this data can be applied to human disease.

From Bruker BioSpin Group 4 Jul 2019

Comprehensive gene activity database could significantly reduce animal use

A comprehensive database of gene activity in mice across ten disease models, which could significantly reduce animal use worldwide, has been developed by scientists at the Francis Crick Institute, which gives a full picture of the immune response to different pathogens.

29 Jun 2019

A metabolic intermediate in the uronic acid pathway impairs lung cancer metastasis

In a study published online in Nature on June 26, research teams led by Dr. YANG Weiwei at the Institute of Biochemistry and Cell Biology of the Chinese Academy of Sciences and Dr. LI Guohui from the Dalian Institute of Chemical Physics of CAS reported a new function of uridine diphosphate glucose (UDP-glucose), a metabolic intermediate in the uronic acid pathway: It impairs lung cancer metastasis by accelerating SNAI1 mRNA decay.

27 Jun 2019

Researchers challenge conventional understanding of cause of Parkinson's

An international team of researchers involving members of the University of Basel's Biozentrum challenges the conventional understanding of the cause of Parkinson's disease.

26 Jun 2019

Study shows how bacteria can destroy host cells from the inside

A bacterial pathogen that typically multiplies outside of host cells can enter and induce the destruction of cells called macrophages, according to a study published June 20 in the open-access journal PLOS Pathogens by Anne-Béatrice Blanc-Potard of the Université de Montpellier in France, and colleagues.

From PLOS ONE 24 Jun 2019

Researchers shed light on bacterial fusion linked to Chlamydia’s pathogenicity

Most people know Chlamydia as the venereal disease that can cause infertility if left untreated. But for researchers studying the causative agent, Chlamydia trachomatis, it's a bacteria with intriguing properties.

24 Jun 2019

Intracellular News and Research

Protein plays important roles in intracellular membrane trafficking in the brain

Loss of cells in the brain found to be associated with stuttering

Chlamydia vaccine shows promise after a successful clinical trial

Discovery of molecular mechanism behind spread of leishmania infection

Researchers identify new transmembrane protein as chloride ion channel

Researchers make scientific breakthrough regarding Leishmania virulence strategy

Research offers new clues into why cognitive functions become impaired with age

Novel therapeutic strategy for treating Lafora Disease shows promise in preclinical study

Common feature that makes cancer cells appear bloated could be their potential weak spot

Aging nerve cells fail to take out the intracellular "trash"

New insights into molecular motors could help treat neurological disorders

New study reveals 'clutch' proteins responsible for putting T cell activation 'into gear'

Study sheds light on complex caspase-1-induced cell death mechanisms

Researchers identify molecular pathway underpinning exercise and improved motor learning

Using NMR to Study Protein Structure, Dynamics and Mechanisms

Comprehensive gene activity database could significantly reduce animal use

A metabolic intermediate in the uronic acid pathway impairs lung cancer metastasis

Researchers challenge conventional understanding of cause of Parkinson's

Study shows how bacteria can destroy host cells from the inside

Researchers shed light on bacterial fusion linked to Chlamydia’s pathogenicity

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