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Insight into immune cell communication may pave the way for new cancer vaccines

In the past decade, immunotherapy has helped save the lives of many cancer patients, many with lung cancer, who might have otherwise faced almost certain death sentences.

9 Dec 2021

Study identifies ORF8 protein as a key COVID-19 causing factor

New study suggests that the SARS-CoV-2 ORF8 protein is the underlying cause behind severe COVID-19 infection.

8 Dec 2021

Breastmilk T cell repertoire is enriched for SARS-CoV-2 Spike-specificity after maternal mRNA vaccination

New study demonstrates that it is possible one day that breastmilk samples will be used to characterize broad mucosal immunity after vaccination.

8 Dec 2021

Hypercoagulability of the blood responsible for cardiac thrombosis in COVID-19 patients

Researchers examined autopsy tissue samples of hearts from patients who died early in the COVID-19 pandemic.

7 Dec 2021

Multiplex proteomic panel assay for assessment of disease severity and outcome prediction in COVID-19

According to the authors of a new study, multiplex protein panel assay could support clinical decision-making, guide the development of novel treatments, and expand the risk assessment procedures for COVID-19.

7 Dec 2021

Scientists develop and characterize variant-specific vaccines against SARS-CoV-2

In a recent study conducted at Yale University, USA, scientists have investigated the immunogenicity of mRNA-based coronavirus disease 2019 (COVID-19) vaccine candidates encoding the spike proteins of different severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants. The findings reveal that the vaccines induce robust immune responses against SARS-CoV-2 variants. The study is currently available on the bioRxiv* preprint server.

6 Dec 2021

Equipment-free handheld microfluidic injection provides visible readout of SARS-CoV-2 detection

In this paper, a group of researchers from Harvard Medical School, McGill University, and Tianjin University describes an on-chip diagnostic technology for the direct detection of SARS-CoV-2 N protein in nasal samples that combines the advantages of hydrodynamic microfluidic filtration and sandwich immunoassay.

5 Dec 2021

Impact of engineered ACE2-Fc on SARS-CoV-2 infection

Researchers employ a structure-guided approach for the development of a series of ACE2-Fc variants using human IgG1 or IgG3 backbone.

1 Dec 2021

Safety and immunogenicity of different COVID-19 booster vaccines

New study findings suggest that booster vaccination with an mRNA-based vaccine has the highest immunogenicity against the COVID-19 Delta variant.

1 Dec 2021

Potentially neurotoxic SARS-CoV-2 protein fragments

Researchers investigate potentially amyloidogenic peptide fragments that could be associated with the neurological symptoms of COVID-19 and long-COVID.

30 Nov 2021

Study on molnupiravir precursor NHC antiviral activity against SARS-CoV-2 variants of concern

In a new study, published on the bioRxiv* preprint server, scientists aimed to determine the reaction of the molnupiravir parent drug (NHC) to different SARS-CoV-2 Variants of Concern (VoCs). They also sought to establish the therapeutic window in a human lung cell model.

29 Nov 2021

Error rate of bacterial DNA polymerase is consistently higher under microgravity, study shows

On 22 May 2019, scientists from Queen's University boarded a modified Falcon 20 aircraft at Ottawa airport. Scheduled was a 'vomit comet' flight, where the plane repeatedly climbs to 8km in a steep parabola, alternating with a descent in freefall.

29 Nov 2021

New discovery about tendon and bone attachment reveals strategies for attaching dissimilar materials

Engineers often use nature to inspire new materials and designs. A discovery by a multi-institutional team of researchers and engineers about how tendon and bone attach in the shoulder joint has uncovered previously unsuspected engineering strategies for attaching dissimilar materials.

29 Nov 2021

Efficacy and safety of an RBD-based recombinant protein COVID-19 vaccine

A study developed a protein-based subunit vaccine, PHH-1V, that consisted of a recombinant RBD fusion heterodimer of the alpha) and beta variants of SARS-CoV-2.

26 Nov 2021

Study explores adverse effects of SARS-CoV-2-induced antibody responses

The authors of a research paper published in the journal Frontiers in Immunology used Sandwich ELISA tests to determine the distribution of IgG sub-classes and complement activation levels in plasma from convalescent individuals.

25 Nov 2021

COVID-19 vaccine boosters to prevent breakthrough SARS-CoV-2 infections in healthy adults

Researchers measured anti-RBD IgG and virus neutralization before and after vaccination with boosters.

25 Nov 2021

New, improved organoids shed light on untreatable form of prostate cancer

A multi-institutional team of investigators led by bioengineer Ankur Singh has developed research tools that shed new light on a virtually untreatable form of prostate cancer, opening a pathway that may lead to novel therapeutics and a glimmer of hope for patients.

24 Nov 2021

Combination of iota-carrageenan and xylitol as a potential nasal spray for COVID

Researchers determine the inhibition capacity of iota-carrageenan and xylitol in three different candidate preservative-free formulations.

24 Nov 2021

Similar antibody responses to spike protein in COVID-19 survivors and vaccine recipients

Researchers conducted a study on COVID-19 convalescent patients and post-vaccinated populations to identify the minimal levels of antibody required to protect against SARS-CoV-2 infection.

24 Nov 2021

Mouthwash containing an antiviral phthalocyanine derivative shortens hospitalizations due to COVID-19

In a study published in the journal Scientific Reports, a research group from Brazil showed how antiviral anionic phthalocyanine derivative used in a mouthwash protocol may not only reduce the symptoms of coronavirus disease (COVID-19), but also hamper the spread of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

23 Nov 2021

micro News and Research

Insight into immune cell communication may pave the way for new cancer vaccines

Study identifies ORF8 protein as a key COVID-19 causing factor

Breastmilk T cell repertoire is enriched for SARS-CoV-2 Spike-specificity after maternal mRNA vaccination

Hypercoagulability of the blood responsible for cardiac thrombosis in COVID-19 patients

Multiplex proteomic panel assay for assessment of disease severity and outcome prediction in COVID-19

Scientists develop and characterize variant-specific vaccines against SARS-CoV-2

Equipment-free handheld microfluidic injection provides visible readout of SARS-CoV-2 detection

Impact of engineered ACE2-Fc on SARS-CoV-2 infection

Safety and immunogenicity of different COVID-19 booster vaccines

Potentially neurotoxic SARS-CoV-2 protein fragments

Study on molnupiravir precursor NHC antiviral activity against SARS-CoV-2 variants of concern

Error rate of bacterial DNA polymerase is consistently higher under microgravity, study shows

New discovery about tendon and bone attachment reveals strategies for attaching dissimilar materials

Efficacy and safety of an RBD-based recombinant protein COVID-19 vaccine

Study explores adverse effects of SARS-CoV-2-induced antibody responses

COVID-19 vaccine boosters to prevent breakthrough SARS-CoV-2 infections in healthy adults

New, improved organoids shed light on untreatable form of prostate cancer

Combination of iota-carrageenan and xylitol as a potential nasal spray for COVID

Similar antibody responses to spike protein in COVID-19 survivors and vaccine recipients

Mouthwash containing an antiviral phthalocyanine derivative shortens hospitalizations due to COVID-19

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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