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Government-funded scientists laid the groundwork for billion-dollar vaccines

When he started researching a troublesome childhood infection nearly four decades ago, virologist Dr. Barney Graham, then at Vanderbilt University, had no inkling his federally funded work might be key to deliverance from a global pandemic.

18 Nov 2020

FDA approves first COVID-19 diagnostic test for at-home use

Today, the U.S. Food and Drug Administration issued an emergency use authorization (EUA) for the first COVID-19 diagnostic test for self-testing at home and that provides rapid results.

18 Nov 2020

Study examines financial penalties levied on large pharmaceutical companies for illegal activities

Some pharmaceutical companies have received criticism for engaging in illegal activities, such as providing kickbacks and bribes, knowingly shipping adulterated or contaminated drugs to pharmacies, and marketing drugs for unapproved uses.

18 Nov 2020

Study demonstrates 24-hour rat liver viability in a normothermic machine perfusion system

In a paper published in TECHNOLOGY, a team of researchers from Massachusetts General Hospital (MGH) has demonstrated 24-hour rat liver viability in a normothermic machine perfusion (NMP) system.

18 Nov 2020

LOX plays a number of key roles in promoting skin and organ fibrosis in scleroderma

A team of researchers at the Medical University of South Carolina (MUSC) has found that the molecule lysyl oxidase (LOX) plays a number of important roles in promoting skin and organ fibrosis in scleroderma, a connective tissue disorder.

17 Nov 2020

Study reveals the metabolic signaling mechanisms that regulate function of eTreg cells

Effector regulatory T cells (eTreg cells) are a specialized subset of white blood cells that keep the immune system in check.

17 Nov 2020

Children's DTP vaccine may provide cross-immunity for COVID-19

He found that the viruses subject to pediatric vaccinations do not have cross-reactive epitopes for SARS-CoV-2, showing they cannot provide protection against COVID-19.

17 Nov 2020

New program can remotely improve cardiovascular health for broad population of patients

Despite being known risk factors for poor cardiovascular outcomes, blood pressure and low-density lipoprotein (LDL) cholesterol remain undertreated among a large proportion of patients.

17 Nov 2020

Scientists uncover new method to produce compounds with anti-cancer properties

In the past decades, cancer has surpassed many other diseases to become the current second leading cause of death globally, with one in six people dying from it.

17 Nov 2020

Natural products and herbal medicines show promise in fight against COVID-19

Researchers in China and the United States have called for more research into the potential prophylactic effects of natural products and herbal medicines on severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and subsequent coronavirus disease 2019 (COVID-19).

17 Nov 2020

Novel protein imaging method could lead to the development of new biomaterials

Scientists have established a new method to image proteins that could lead to new discoveries in disease through biological tissue and cell analysis and the development of new biomaterials that can be used for the next generation of drug delivery systems and medical devices.

17 Nov 2020

Combination of ticagrelor and aspirin reduces subsequent stroke risk in patients with heart plaque

Patients with plaque build-up in their arteries, who suffered a transient ischemic attack (TIA) or a minor ischemic stroke, also called a warning stroke, and were treated with the newer blood thinner ticagrelor plus aspirin were 27% less likely to have another stroke within 30 days, according to late-breaking research presented today at the American Heart Association's Scientific Sessions 2020.

17 Nov 2020

Hydrogen therapy may help severely ill COVID-19 patients

Researchers from the Department of Critical Care Medicine, Sichuan Provincial People's Hospital, Chengdu in China, have explored the possibility of using hydrogen therapy on severely ill COVID-19 patients. The team published their study's findings, titled "Hydrogen: A Potential New Adjuvant Therapy for COVID-19 Patients," in the latest issue of the journal Frontiers in Pharmacology.

17 Nov 2020

Novel drug reduces the risk of cardiovascular events for patients with Type 2 diabetes, kidney disease

A novel diabetes medication significantly reduces the risk of hospitalization for heart failure, heart attack and stroke, in patients with Type 2 diabetes and chronic kidney disease, according to late breaking research presented today at the American Heart Association's Scientific Sessions 2020.

17 Nov 2020

Several hepatitis C drugs can inhibit crucial protein in SARS-CoV-2

Experiments led by researchers at the Department of Energy's Oak Ridge National Laboratory have determined that several hepatitis C drugs can inhibit the SARS-CoV-2 main protease, a crucial protein enzyme that enables the novel coronavirus to reproduce.

17 Nov 2020

Discovery of 'Achilles heel' in protein crucial to HIV virulence could lead to new class of drugs

The discovery of a potential "Achilles heel" in Nef, the protein that is crucial to HIV virulence and its capacity to trigger AIDS, paves the way for the development of a new class of drugs against the virus.

17 Nov 2020

Researchers identify two key biomarkers contributing to gastric cancer metastasis

A research team led by Professor Wang Wen-ching of the Institute of Molecular and Cellular Biology, National Tsing Hua University has exploited the power of big data to identify two key biomarkers contributing to the proliferation and metastasis of gastric (stomach) cancer.

17 Nov 2020

Drugs News and Research

Government-funded scientists laid the groundwork for billion-dollar vaccines

FDA approves first COVID-19 diagnostic test for at-home use

Study examines financial penalties levied on large pharmaceutical companies for illegal activities

Study demonstrates 24-hour rat liver viability in a normothermic machine perfusion system

LOX plays a number of key roles in promoting skin and organ fibrosis in scleroderma

Study reveals the metabolic signaling mechanisms that regulate function of eTreg cells

Children's DTP vaccine may provide cross-immunity for COVID-19

New program can remotely improve cardiovascular health for broad population of patients

Scientists uncover new method to produce compounds with anti-cancer properties

Natural products and herbal medicines show promise in fight against COVID-19

Novel protein imaging method could lead to the development of new biomaterials

Combination of ticagrelor and aspirin reduces subsequent stroke risk in patients with heart plaque

Hydrogen therapy may help severely ill COVID-19 patients

Novel drug reduces the risk of cardiovascular events for patients with Type 2 diabetes, kidney disease

Several hepatitis C drugs can inhibit crucial protein in SARS-CoV-2

Discovery of 'Achilles heel' in protein crucial to HIV virulence could lead to new class of drugs

Researchers identify two key biomarkers contributing to gastric cancer metastasis

Study shows favorable impact of medication on cardiac structure and function

First intratumoral injection approved by FDA for treating non-metastatic mast cell tumors in dogs

Targeting BCAP with new drugs could benefit people with inflammatory bowel disease

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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