Hormone News and Research

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A hormone is a chemical released by one or more cells that affects cells in other parts of the organism. Only a small amount of hormone is required to alter cell metabolism. It is essentially a chemical messenger that transports a signal from one cell to another.

Takeda submits NDA for Alogliptin (SYR-322) in the U.S.

Takeda Pharmaceutical Company Limited (Takeda) has announced that Takeda Global Research & Development Center, Inc. submitted a New Drug Application (NDA) to the United States Food and Drug Administration (FDA) for alogliptin (development code: SYR-322), a highly selective dipeptidyl peptidase-4 (DPP-4) inhibitor under investigation for the treatment of type 2 diabetes.

7 Jan 2008

Pregnant women who are overweight/obese set the stage for offspring's obesity risk

The number of overweight and obese Americans continues to grow rapidly. Today, 50 percent of adults are overweight and up to 20 percent are obese. While the number of overweight/obese children is at an all time high, the steady increase of overweight infants -- individuals under 11 months old -- is alarming.

4 Jan 2008

Peptide hormone found in the body prevents obesity and diabetes

A new study finds that a chemical found in the body is capable of promoting weight loss, improving insulin resistance and reversing diabetes in an animal model.

4 Jan 2008

Testosterone therapy and mental function in healthy older men

When we think about the powers of testosterone, we usually do not consider mental processes.

3 Jan 2008

Hormone therapy in younger menopausal women

Could hormone therapy, when begun near the onset of menopause, prevent or delay the onset of atherosclerosis, more commonly called hardening of the arteries.

3 Jan 2008

No excess cardiovascular risk from HRT for most patients

An American Association of Clinical Endocrinologists (AACE) analysis of several studies monitoring the impact of Hormone Replacement Therapy (HRT) shows young women in early menopause may not only have no increased cardiovascular risk from the therapy, but may indeed show benefit in the future.

3 Jan 2008

Testosterone supplementation in older men

Older men with low testosterone levels who received testosterone supplementation increased lean body mass and decreased body fat, but were no stronger and had no improvement in mobility or cognition compared with men who did not use the supplement, according to a study in the January 2 issue of JAMA.

2 Jan 2008

Deep sleep maintains normal glucose control

Suppression of slow-wave sleep in healthy young adults significantly decreases their ability to regulate blood-sugar levels and increases the risk of type 2 diabetes, report researchers at the University of Chicago Medical Center in the "Early Edition" of the Proceedings of the National Academy of Science, available online as soon as Dec. 31, 2007.

2 Jan 2008

New drug target for treatment-resistant prostate cancer

Scientists at Jefferson's Kimmel Cancer Center in Philadelphia have found that a signaling protein that is key to prostate cancer cell growth is turned on in nearly all recurrent prostate cancers that are resistant to hormone therapy.

2 Jan 2008

A happy marriage bolsters a woman's physiological recovery from work

That's the suggestion from a new UCLA study that tracked levels of cortisol, a key stress hormone, among 30 Los Angeles married couples involved in one of our age's trickiest juggling acts - raising kids when both parents work full time.

2 Jan 2008

Children short of sleep three times as likely to be obese

According to new research by scientists in New Zealand children who do not get enough sleep face an increased risk of obesity and behavioral problems.

2 Jan 2008

A happy marriage eases a working woman's stress

According to new gender research, a happy marriage is more likely to reduce a working woman's stress levels than her husband's.

2 Jan 2008

Discovery of potential oral treatment for diabetes

Research in the Department of Biology at the Faculty of Science and Science Education of the University of Haifa has discovered a substance that may become an oral treatment for diabetes and its complications.

28 Dec 2007

Medical myths laid to rest

New research from the United States has revealed that a number of commonly-held medical beliefs are in fact just medical myths.

27 Dec 2007

RNA interference therapy heals growth deficiency disorder in a live animal

A team of Vanderbilt researchers have demonstrated for the first time that a new type of gene therapy, called RNA interference, can heal a genetic disorder in a live animal.

20 Dec 2007

New drug that cuts risk of cardiovascular disease shows promise

The first clinical trial of a new kind of drug to cut the risk of cardiovascular disease has been found safe and effective at dropping levels of "bad" low density lipoprotein (LDL) cholesterol by as much as 40 percent.

18 Dec 2007

Oral diabetes medication - new guidelines

A pair of plain-language guides that outline the latest scientific evidence on the effectiveness and safety of oral medications for adults with type 2 diabetes are now available from HHS' Agency for Healthcare Research and Quality.

18 Dec 2007

Effectiveness and risks of six bisphosphonates for osteoporosis

Many medications reduce the risk of bone fractures in people with osteoporosis, but the most commonly used drugs - bisphosphonates - have not been proven more effective than alternatives, according to a new report funded by the Agency for Healthcare Research and Quality (AHRQ), part of the U.S. Department of Health and Human Services.

18 Dec 2007

How might lack of light cause depression?

People troubled by depression usually experience their dark moods in an on-again, off-again fashion.

18 Dec 2007

Caution on use of Vasopressin in septic shock

Vasopressin should be used with great caution for the treatment of hypotension in septic shock, according to results from an international research team published in the online open access journal Critical Care.

14 Dec 2007