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Molecular target discovery opens new pathways for developing effective anti-angiogenic cancer therapy

Researchers with The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute have identified a new molecular drug target that could result in new cancer drugs with fewer side effects.

20 May 2022

Hyperinsulinemic patients with breast cancer may be responsive to metabolism-targeting treatments

Scientists at Yale Cancer Center have found that patients with breast cancer and high levels of insulin in the blood may be responsive to metabolism-targeting treatments, which in turn may improve the effectiveness of subsequent chemotherapy treatments.

20 May 2022

Clopidogrel monotherapy linked with reduced risk of net adverse clinical events, study finds

Results from a real-world study investigating safety and effectiveness of clopidogrel versus aspirin monotherapy beyond 12 months after PCI in high-risk patients during the chronic maintenance period.

20 May 2022

Low-dose apixaban treatment reduces recurrence of venous thromboembolism compared to anticoagulant discontinuation after negative D-dimer

Patients who have suffered from a first episode of unprovoked venous thromboembolism (VTE) have an eight times higher risk of recurrence if they stop treatment after repeated negative D-dimer tests, instead of continuing with low-dose anticoagulant (apixaban).

20 May 2022

Probiotic supplements accelerate the maturation of microbiome in extremely preterm infants

University of Calgary researchers have shown probiotic supplements can help form a healthy microbiome in the gut of the tiniest infants who are born without a fully formed gut microbiome.

20 May 2022

‘Watch and wait’ approach may improve outcomes for very frail patients than emergency surgery

New research published in Anaesthesia (a journal of the Association of Anaesthetists) shows that for patients who are very frail, it may be better to adopt a 'watch and wait' approach rather than proceeding to emergency surgery for five common medical emergencies.

20 May 2022

Serologic response to SARS-CoV-2 may predict COVID-19 severity

A new study reported that antibody titers against SARS-CoV-2 could serve as a marker for the severity of COVID-19.

20 May 2022

Studies provide insight into how long COVID-19 immunity lasts and nature of immune recall

How does the immune system remember and recognize viral invaders it has encountered in the past? A trio of newly published studies of people infected with SARS-CoV-2, vaccinated against the virus or both, are providing tantalizing new clues about the factors that influence the speed and magnitude of the immune system's response to subsequent infection with variants of SARS-CoV-2.

19 May 2022

New funding boost to combat antibiotic resistance

Antibiotics have saved countless lives since they were introduced in the 1940s, curing infections and making procedures like chemotherapy and surgeries safer. But their effectiveness is waning.

19 May 2022

Novel surface treatment could help improve safety of medical devices, prevent hospital infections

A hospital or medical clinic might be the last place you'd expect to pick up a nasty infection, but approximately 1.7 million Americans do each year, resulting in nearly 100,000 deaths from infection-related complications and roughly $30 billion in direct medical costs.

19 May 2022

Study validates long-term safety and efficacy of Harmony transcatheter pulmonary valve implant

A study of one year outcomes in the largest cohort to date of Harmony transcatheter pulmonary valve (TPV) patients with congenital heart disease (CHD) and severe pulmonary regurgitation (PR) was presented today as late-breaking clinical research at the Society for Cardiovascular Angiography & Interventions 2022 Scientific Sessions.

19 May 2022

Study estimates the global RSV disease burden in children under five in 2019

A new study published in The Lancet estimates that RSV-attributable acute lower respiratory infection was responsible for more than 100,000 deaths in children under five across the globe in 2019.

19 May 2022

SARS-CoV-2 Omicron linked to rise in croup in young children

A recent Pediatrics study assesses the causative relationship between SARS-CoV-2 infection and croup or “barking cough” in children.

19 May 2022

Treating pediatric psychiatric disorders with psychotropic drugs reduces later substance use disorder risk

One half of psychiatric and substance use disorders start by the age of 18; three-quarters by age 24. While these are concerning statistics, a new study from Massachusetts General Hospital finds that treating psychiatric disorders with psychotropic medications in children and adolescents does not increase the risk of developing substance use, misuse, or substance use disorder (SUD).

19 May 2022

Preclinical study may pave the way toward prevention and recovery of neonatal brain injuries

The findings of a new pre-clinical study published in The Journal of Neuroscience are helping pave the way toward better understanding, prevention and recovery of neonatal brain injuries.

19 May 2022

Islet cell transplant program offers an effective treatment for patients with hard-to-control Type 1 diabetes

After 20 years of perfecting their technique, the team behind the largest islet cell transplant program in the world reports the procedure is a safe, reliable and life-changing treatment for people with hard-to-control diabetes.

19 May 2022

Intestinal microbiome may contribute to the pathogenesis of MSI colon cancers, study suggests

Investigators from Rutgers Cancer Institute of New Jersey, New Jersey's only National Cancer Institute- Designated Comprehensive Cancer Center, led a collaborative study to examine the patterns of druggable oncogenic fusions in colon cancer specimens including microsatellite-stable and unstable (MSI) tumors.

19 May 2022

Novel non-invasive method for predicting complications in chronic liver disease

In a recent study, an interdisciplinary research team from MedUni Vienna showed that functional magnetic resonance imaging (fMRI) can be used as a non-invasive method for predicting complications in chronic liver disease.

19 May 2022

Study finds gender-based disparity in life-saving TXA treatment

Injured women are half as likely as men to receive the life-saving drug tranexamic acid (TXA) even though the treatment is equally effective regardless of sex, according to new research in the British Journal of Anaesthesia.

19 May 2022

Using 'off-the-shelf' engineered stem cell based therapy for treating glioblastomas post-surgery

Glioblastomas (GBMs) are highly aggressive cancerous tumors of the brain and spinal cord. Brain cancers like GBM are challenging to treat because many cancer therapeutics cannot pass through the blood-brain barrier, and more than 90 percent of GBM tumors return after being surgically removed, despite surgery and subsequent chemo- and radiation therapy being the most successful way to treat the disease.

19 May 2022

Hospital News and Research

Molecular target discovery opens new pathways for developing effective anti-angiogenic cancer therapy

Hyperinsulinemic patients with breast cancer may be responsive to metabolism-targeting treatments

Clopidogrel monotherapy linked with reduced risk of net adverse clinical events, study finds

Low-dose apixaban treatment reduces recurrence of venous thromboembolism compared to anticoagulant discontinuation after negative D-dimer

Probiotic supplements accelerate the maturation of microbiome in extremely preterm infants

‘Watch and wait’ approach may improve outcomes for very frail patients than emergency surgery

Serologic response to SARS-CoV-2 may predict COVID-19 severity

Studies provide insight into how long COVID-19 immunity lasts and nature of immune recall

New funding boost to combat antibiotic resistance

Novel surface treatment could help improve safety of medical devices, prevent hospital infections

Study validates long-term safety and efficacy of Harmony transcatheter pulmonary valve implant

Study estimates the global RSV disease burden in children under five in 2019

SARS-CoV-2 Omicron linked to rise in croup in young children

Treating pediatric psychiatric disorders with psychotropic drugs reduces later substance use disorder risk

Preclinical study may pave the way toward prevention and recovery of neonatal brain injuries

Islet cell transplant program offers an effective treatment for patients with hard-to-control Type 1 diabetes

Intestinal microbiome may contribute to the pathogenesis of MSI colon cancers, study suggests

Novel non-invasive method for predicting complications in chronic liver disease

Study finds gender-based disparity in life-saving TXA treatment

Using 'off-the-shelf' engineered stem cell based therapy for treating glioblastomas post-surgery

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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