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Plitidepsin in combination with dexamethasone shows top-line results in Phase III multiple myeloma trial

PharmaMar today announced positive top-line results of its Phase III clinical trial -ADMYRE- with Aplidin (plitidepsin) in combination with dexamethasone versus dexamethasone alone in patients with relapsed/refractory multiple myeloma (MM).

2 Apr 2016

GHIT Fund invests in two innovative malaria eradication tools

The Global Health Innovative Technology Fund (GHIT Fund) announced today that it’s investing US$1,383,785 in a pair of innovative malaria eradication tools—a vaccine that could block transmission of two species of the deadly disease and a rapid field test that can reveal a malaria infection in minutes.

1 Apr 2016

FDA approves Defitelio to treat hepatic veno-occlusive disease in adults, children

The U.S. Food and Drug Administration today approved Defitelio (defibrotide sodium) to treat adults and children who develop hepatic veno-occlusive disease (VOD) with additional kidney or lung abnormalities after they receive a stem cell transplant from blood or bone marrow called hematopoietic stem cell transplantation (HSCT).

31 Mar 2016

European Medicines Agency approves first-ever treatment for hereditary factor X deficiency

Bio Products Laboratory, Limited (BPL) today announced that the European Medicines Agency has granted marketing authorisation for Coagadex.

31 Mar 2016

Twitter-based smoking cessation programs twice as successful as traditional methods in helping smokers quit

A new study by researchers from UC Irvine and Stanford University found subjects in one of the first real-time, fully automated, Twitter-based smoking intervention programs - Tweet2Quit -- were twice as successful at kicking the habit as those using traditional methods. The new findings were recently published online in Tobacco Control, an international peer reviewed journal. The print version of the research is forthcoming.

30 Mar 2016

Researchers develop new technique to study blood vessel inflammation

Nanotechnology has led to better diagnostic techniques and more effective treatments for a variety of illnesses. Tiny devices measuring between 1 and 100 micrometers--one micrometer is equal to one millionth of a meter--enable scientists to observe cell activity and deliver drugs to individual cells--a breakthrough that is on the verge of revolutionizing precision medicine for treatment of diseases such as cancer.

30 Mar 2016

Research describes first new mouse model for Zika infection in decades

Efforts to combat the rapid spread of Zika virus got a boost this week as researchers at the University of Texas Medical Branch, Galveston (UTMB) announced the first peer-reviewed publication of a mouse model for Zika infection reported in decades.

30 Mar 2016

New stem cell-based therapies for Parkinson's Disease may be on the horizon

As stem cell-based therapies are moving rapidly towards clinical trials, treatments for Parkinson's Disease (PD), an incurable condition, may be on the horizon. A recent announcement of a Phase I/IIa clinical trial involving transplantation of stem cells into the first human subjects has raised hope among patients and sparked discussions in the research community.

30 Mar 2016

Scientists develop triple-stage 'cluster bomb' system to deliver cisplatin drug through nanoparticles

Scientists have devised a triple-stage "cluster bomb" system for delivering the chemotherapy drug cisplatin, via tiny nanoparticles designed to break up when they reach a tumor.

30 Mar 2016

Concussion-related symptoms improve following initial session of OMT

Two case reports published in The Journal of the American Osteopathic Association document improvements in concussion-related symptoms following an initial session of osteopathic manipulative treatment (OMT).

29 Mar 2016

Oregon's new birth control law could improve access to all forms of contraception

Researchers at Oregon Health & Science University, University of Minnesota School of Public Health and George Mason University applaud Oregon's new birth control law which allows women age 18 or older to obtain some methods of hormonal contraception directly from pharmacies, without having to visit a prescribing clinician, yet note how the law could go even further to improve access to all forms of contraception, according to a viewpoint article published in the Journal of the American Medical Association today.

29 Mar 2016

CCN5 protein reverses cardiac fibrosis in heart failure models

CCN5, a matricellular protein, has been found to reverse established cardiac fibrosis in heart failure models, according to a study led by Roger J. Hajjar, MD, Professor of Medicine and Director of the Cardiovascular Research Center at the Icahn School of Medicine at Mount Sinai, and Woo Jin Park, PhD, Professor of Life Sciences at the Gwangju Institute of Science and Technology, South Korea.

29 Mar 2016

Common genetic defect in beta cells may underlie both known forms of diabetes

New research by Dr. Sylvie Lesage, scientist at Maisonneuve-Rosemont Hospital and associate research Professor at University of Montreal, just published in the prestigious international scientific journal Nature Genetics, has discovered that a common genetic defect in beta cells may underlie both known forms of diabetes.

25 Mar 2016

Cinqair (reslizumab) approved for treatment of severe asthma

The U.S. Food and Drug Administration today approved Cinqair (reslizumab) for use with other asthma medicines for the maintenance treatment of severe asthma in patients aged 18 years and older. Cinqair is approved for patients who have a history of severe asthma attacks (exacerbations) despite receiving their current asthma medicines.

23 Mar 2016

Scientists provide overview of most promising compounds to combat prostate cancer

Scientists from MIPT (Moscow Institute of Physics and Technology), MSU (Moscow State University), and National University of Science and Technology “MISIS” provided an overview of the most promising compounds which can be used as medications for prostate cancer.

23 Mar 2016

Subcutaneous injection of raltegravir can protect against vaginal HIV transmission

Vaginal transmission accounts for the majority of new HIV infections worldwide. Forms of pre-exposure prophylaxis (PrEP) such as vaginal gels and vaginal rings designed to prevent HIV transmission have encountered poor efficacy in human trials due to problems with adherence.

22 Mar 2016

Shigella dysenteriae pathogen probably originated in Europe, genetic study reveals

The largest genetic study on the bacterium responsible for epidemic dysentery has revealed that the Shigella dysenteriae pathogen, which remains a real scourge in Africa and Asia, probably originated in Europe.

22 Mar 2016

Cutting-edge vascular implant technology available at PinnacleHealth for patients with claudication

PinnacleHealth CardioVascular Institute enrolled the first patient in Pennsylvania into the TOBA II clinical on October 19, 2015. This trial is to assess the safety and efficacy of a vascular implant for the treatment of dissections (tearing in the artery wall) that occur following balloon angioplasty (PTA) of the main artery in the leg.

22 Mar 2016

GEMINI LTS study: Patients with active ulcerative colitis report clinical improvements with vedolizumab treatment

Takeda Pharmaceutical Company Limited, (“Takeda”) today announced that the interim findings from the GEMINI Long-Term Safety (LTS) study were presented during the 2016 European Crohn's and Colitis Organisation (ECCO) Annual Scientific Meeting in Amsterdam, The Netherlands.

22 Mar 2016

UGA investigators find viable treatment for prostate cancer

Researchers at the University of Georgia have created a new therapeutic for prostate cancer that has shown great efficacy in mouse models of the disease. They published their findings recently in the journal Nanomedicine: Nanotechnology, Biology and Medicine.

22 Mar 2016

Efficacy News and Research

Plitidepsin in combination with dexamethasone shows top-line results in Phase III multiple myeloma trial

GHIT Fund invests in two innovative malaria eradication tools

FDA approves Defitelio to treat hepatic veno-occlusive disease in adults, children

European Medicines Agency approves first-ever treatment for hereditary factor X deficiency

Twitter-based smoking cessation programs twice as successful as traditional methods in helping smokers quit

Researchers develop new technique to study blood vessel inflammation

Research describes first new mouse model for Zika infection in decades

New stem cell-based therapies for Parkinson's Disease may be on the horizon

Scientists develop triple-stage 'cluster bomb' system to deliver cisplatin drug through nanoparticles

Concussion-related symptoms improve following initial session of OMT

Oregon's new birth control law could improve access to all forms of contraception

CCN5 protein reverses cardiac fibrosis in heart failure models

Common genetic defect in beta cells may underlie both known forms of diabetes

Cinqair (reslizumab) approved for treatment of severe asthma

Scientists provide overview of most promising compounds to combat prostate cancer

Subcutaneous injection of raltegravir can protect against vaginal HIV transmission

Shigella dysenteriae pathogen probably originated in Europe, genetic study reveals

Cutting-edge vascular implant technology available at PinnacleHealth for patients with claudication

GEMINI LTS study: Patients with active ulcerative colitis report clinical improvements with vedolizumab treatment

UGA investigators find viable treatment for prostate cancer

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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