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Novel approach to gene editing bypasses disease-causing mutations in a gene

A new approach to gene editing using the CRISPR/Cas9 system bypasses disease-causing mutations in a gene, enabling treatment of genetic diseases linked to a single gene, such as cystic fibrosis, certain types of sickle cell anemia, and other rare diseases.

21 Apr 2021

Listening to music can help older adults sleep better, finds study

A new study published in the Journal of the American Geriatrics Society has found that listening to music can help older adults sleep better.

21 Apr 2021

Interfering RNA nanoparticles could be a potential COVID-19 therapy

Study shows lipid nanoparticle-based siRNA is potent in suppressing severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the causative agent of coronavirus disease 2019 (COVID-19) – in cells as well as in mice models.

21 Apr 2021

Listening to music before going to bed can improve sleep quality among older adults

Listening to music before going to be can improve sleep quality among older adults, according to an analysis of all relevant published clinical trials.

21 Apr 2021

Characterization of lab-produced neutralizing antibodies targeting SARS-CoV-2

A new study led by Hans-Martin Jäck of the Friedrich-Alexander University Erlangen-Nuremberg in Germany engineered clusters of neutralizing monoclonal antibodies using a transgenic mouse model. A unique characteristic for the antibodies was the different ways it bound to the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and the overall reduction in the viral spread for human ACE2.

21 Apr 2021

Researchers identify differences in immune response in asymptomatic versus severe COVID-19 cases

The largest study of its type in the UK has identified differences in the immune response to COVID-19, between people with no symptoms, compared to those suffering a more serious reaction to the virus.

21 Apr 2021

Widely available HIV testing and treatment services increase life expectancy

Life expectancy among adults living with HIV receiving antiretroviral therapy (ART) in Latin America and the Caribbean has increased significantly since HIV testing and treatment services became more widely available, according to research published today in The Lancet HIV journal.

21 Apr 2021

Rare compound found in a shrub could help fight previously 'undruggable' cancer protein

A chemist from Purdue University has found a way to synthesize a compound to fight a previously "undruggable" cancer protein with benefits across a myriad of cancer types.

20 Apr 2021

Study investigates severe lung injuries among e-cigarette users in rural Appalachia

Just as e-cigarette ingredients can vary from one region to another, the health effects of vaping can have regional characteristics as well. A new study out of West Virginia University suggests that rural e-cigarette users are older--and often get sicker--than their urban counterparts.

20 Apr 2021

Genethon announces dosing of first patient at pediatric clinical trial platform for neuromuscular diseases

A first participant was dosed at I-Motion, the pediatric clinical trial platform for neuromuscular diseases located at Trousseau hospital in Paris, as part of the gene therapy trial in Duchenne muscular dystrophy (DMD) conducted by Genethon.

20 Apr 2021

Study identifies higher mortality risk for women with back pain

New research from Boston Medical Center identifies elevated mortality risk for women with back pain when compared to women without back pain. Back pain was not associated with mortality among men indicating long-term consequences of back pain may differ by sex.

20 Apr 2021

Probiotic L. acidophilus can effectively treat intestinal inflammation, research shows

Intestinal epithelial tight junctions (TJs) act as a functional and structural barrier against harmful antigens that promote intestinal inflammation in inflammatory bowel disease (IBD) and other inflammatory conditions of the gut.

20 Apr 2021

Targeted therapy may be of great benefit in early stage breast cancer

Targeted therapy in early stages of breast cancer can pave the way for a notable higher success rate, shows a study from the University of Bergen, Norway.

20 Apr 2021

MIND Institute study of anxiety in children with ASD has now expanded to offer online treatment

It's now easier than ever to take part in a study that includes treatment for anxiety in children with autism spectrum disorder (ASD) at the UC Davis MIND Institute's Autism Center of Excellence.

20 Apr 2021

1 in 6 patients with colorectal cancer found to have inherited genetic mutations

A new Mayo Clinic study bolsters evidence that colorectal cancer is often imprinted in family genes and passed on from one generation to the next.

20 Apr 2021

Nearly 20% of U.S. adults experience chronic pain

Chronic pain is among the most common chronic conditions in the United States, but estimates of its prevalence and impact vary widely.

20 Apr 2021

From rotten teeth to advanced cancer, patients feel the effects of treatment delays

With medical visits picking up again among patients vaccinated against Covid-19, health providers are starting to see the consequences of a year of pandemic-delayed preventive and emergency care as they find more advanced cancer and rotting and damaged teeth, among other ailments.

20 Apr 2021

Policies designed to prevent opioid misuse may limit access to pain-relieving drugs

Policies designed to prevent the misuse of opioids may have the unintended side effect of limiting access to the pain-relieving drugs by terminally ill patients nearing the end of their life, new research led by the Oregon State University College of Pharmacy suggests.

20 Apr 2021

Study identifies strengths and specific challenges among young autistic drivers

A collaborative study from the Center for Injury Research and Prevention (CIRP) and the Center for Autism Research (CAR) at Children's Hospital of Philadelphia (CHOP) identified clear strengths and a series of specific challenges autistic adolescents experience while learning to drive.

20 Apr 2021

Immune tolerance in hemophilia can be modulated by B cell activating factor

A group of scientists have just made a key discovery that could prevent and eradicate immune responses that lead to treatment failure in about one-third of people with severe hemophilia A.

20 Apr 2021

Therapy News and Research

Novel approach to gene editing bypasses disease-causing mutations in a gene

Listening to music can help older adults sleep better, finds study

Interfering RNA nanoparticles could be a potential COVID-19 therapy

Listening to music before going to bed can improve sleep quality among older adults

Characterization of lab-produced neutralizing antibodies targeting SARS-CoV-2

Researchers identify differences in immune response in asymptomatic versus severe COVID-19 cases

Widely available HIV testing and treatment services increase life expectancy

Rare compound found in a shrub could help fight previously 'undruggable' cancer protein

Study investigates severe lung injuries among e-cigarette users in rural Appalachia

Genethon announces dosing of first patient at pediatric clinical trial platform for neuromuscular diseases

Study identifies higher mortality risk for women with back pain

Probiotic L. acidophilus can effectively treat intestinal inflammation, research shows

Targeted therapy may be of great benefit in early stage breast cancer

MIND Institute study of anxiety in children with ASD has now expanded to offer online treatment

1 in 6 patients with colorectal cancer found to have inherited genetic mutations

Nearly 20% of U.S. adults experience chronic pain

From rotten teeth to advanced cancer, patients feel the effects of treatment delays

Policies designed to prevent opioid misuse may limit access to pain-relieving drugs

Study identifies strengths and specific challenges among young autistic drivers

Immune tolerance in hemophilia can be modulated by B cell activating factor

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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