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SNX-5422 could make an effective COVID-19 prophylactic, says study

SNX-5422 is a heat shock protein 90 (Hsp90) inhibitor currently undergoing clinical trials as a cancer therapeutic. A recent study examines the applicability of repurposing the drug towards severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) replication inhibition.

25 Feb 2021

Canadian pilot study uses gene therapy to successfully treat patients with Fabry disease

Results of a world-first Canadian pilot study on patients treated with gene therapy for Fabry disease show that the treatment is working and safe.

25 Feb 2021

'Miracle poison' can target a variety of different proteins

Researchers prove they can engineer proteins called proteases to find new targets with high selectivity, a critical advance toward potential new treatments for everything from neuro-regeneration to cytokine storm.

25 Feb 2021

CAR T-cell therapy produces deep, sustained remissions in patients with relapsed myeloma

In a major advance in the treatment of multiple myeloma, a CAR T-cell therapy has generated deep, sustained remissions in patients who had relapsed from several previous therapies, an international clinical trial has found.

24 Feb 2021

Study shows reliability and robustness of injectable anti-obesity medication

A second study of the injectable anti-obesity medication, semaglutide, has confirmed the large weight losses reported in a study earlier this month, establishing the reliability and robustness of this new drug.

24 Feb 2021

A new combination therapy for treating rare, fatal Sanfilippo syndrome in children

A study aiming to develop a new therapeutic technique could bring a revolution in our approach to treating rare, fatal Sanfilippo syndrome, a disorder that affects children as young as 2 years old and leads to childhood dementia and premature death.

24 Feb 2021

Tumors use unique mechanism to switch on regulatory T cells for protection

Immunologists at St. Jude Children's Research Hospital have discovered that tumors use a unique mechanism to switch on regulatory T cells to protect themselves from attack by the immune system.

24 Feb 2021

New center established at NYU Langone Health to expand psychedelic research and training

Philanthropic support from several donors totaling over $10 million will allow NYU Langone Health to advance its already world-renowned reputation in the field of psychedelic medicine through the establishment of a one-of-a-kind center dedicated to expanding research and professional medical training in this resurging field.

24 Feb 2021

Study shows prevalence of inappropriate treatment for uncomplicated urinary tract infections

Nearly half of women with uncomplicated urinary tract infections received the wrong antibiotics and almost three-quarters received prescriptions for longer than necessary, with inappropriately long treatment durations more common in rural areas, according to a study of private insurance claims data published today in Infection Control & Hospital Epidemiology, the journal of the Society for Healthcare Epidemiology of America.

24 Feb 2021

Magnesium-based micromotors used to improve rheumatoid arthritis symptoms

Rheumatoid arthritis is a chronic inflammatory disorder marked by joint pain, swelling and damage. Although medications, such as steroids, anti-inflammatory drugs and immunosuppressants, can help slow joint destruction and relieve pain, they have side effects and aren't completely successful.

24 Feb 2021

Study offers new insights into "Niemann-Pick type C disease"

In the journal Nature Communications, scientists of the German Center for Neurodegenerative Diseases (DZNE) report new findings on the mechanisms of "Niemann-Pick type C disease" (NPC).

24 Feb 2021

Endocrine-targeted therapies can prevent and treat endometrial cancer recurrence

In a new study led by Yale Cancer Center, researchers demonstrate sex hormones and insulin growth factors are associated with recurrence risk of endometrial cancer.

24 Feb 2021

New platform can help treat neurodegenerative diseases through regenerative medicine

Imagine if surgeons could transplant healthy neurons into patients living with neurodegenerative diseases or brain and spinal cord injuries.

24 Feb 2021

SARS-CoV-2 variants emerge during humoral immunity phase of acute COVID-19

A new preprint research paper posted to the bioRxiv server reports the rapid emergence of variants within an infected individual. The evolution of the virus within an infected host is not excluded by the close similarity between the consensus sequences of single-person SARS-CoV-2, since the number of viral copies is at its peak soon after infection occurs and before the host develops adaptive immunity.

23 Feb 2021

Slight differences can help distinguish between two similar pediatric brain conditions

Slight differences in clinical features can help physicians distinguish between two rare but similar forms of autoimmune brain inflammation in children, a new study by UT Southwestern scientists suggests.

23 Feb 2021

Phase 1 clinical trial shows promising results for monoclonal antibodies against MERS coronavirus

A randomized, placebo-controlled Phase 1 clinical trial of two monoclonal antibodies (mAbs) directed against the coronavirus that causes Middle East respiratory syndrome (MERS) found that they were well tolerated and generally safe when administered simultaneously to healthy adults.

23 Feb 2021

GSK-3 inhibitors show promise in treating coronavirus infections

Researchers in the United States have suggested a new approach to treating infection with coronaviruses such as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19).

23 Feb 2021

'Phage therapy' helps treat mice infected with multidrug-resistant Klebsiella pneumoniae

Using viruses instead of antibiotics to tame troublesome drug-resistant bacteria is a promising strategy, known as bacteriophage or "phage therapy."

23 Feb 2021

mRNA Therapeutics – Analytical and Bioanalytical Characterization

NewsMed interviews Anette Bak from AstraZeneca about her research on developments in mRNA therapeutics that she will present at Pittcon 2021.

From Pittcon 23 Feb 2021

Researchers investigate how CF patients respond to COVID-19

So far, based on clinical data, patients with cystic fibrosis (CF) don't appear to be especially susceptible to COVID-19, and when they do get infected, they don't seem to get sicker. But Ruobing (Ruby) Wang, MD, a physician-scientist in the Division of Pulmonary Medicine at Boston Children's Hospital, cares for patients with CF and thinks there is more to the story.

23 Feb 2021

Therapy News and Research

SNX-5422 could make an effective COVID-19 prophylactic, says study

Canadian pilot study uses gene therapy to successfully treat patients with Fabry disease

'Miracle poison' can target a variety of different proteins

CAR T-cell therapy produces deep, sustained remissions in patients with relapsed myeloma

Study shows reliability and robustness of injectable anti-obesity medication

A new combination therapy for treating rare, fatal Sanfilippo syndrome in children

Tumors use unique mechanism to switch on regulatory T cells for protection

New center established at NYU Langone Health to expand psychedelic research and training

Study shows prevalence of inappropriate treatment for uncomplicated urinary tract infections

Magnesium-based micromotors used to improve rheumatoid arthritis symptoms

Study offers new insights into "Niemann-Pick type C disease"

Endocrine-targeted therapies can prevent and treat endometrial cancer recurrence

New platform can help treat neurodegenerative diseases through regenerative medicine

SARS-CoV-2 variants emerge during humoral immunity phase of acute COVID-19

Slight differences can help distinguish between two similar pediatric brain conditions

Phase 1 clinical trial shows promising results for monoclonal antibodies against MERS coronavirus

GSK-3 inhibitors show promise in treating coronavirus infections

'Phage therapy' helps treat mice infected with multidrug-resistant Klebsiella pneumoniae

mRNA Therapeutics – Analytical and Bioanalytical Characterization

Researchers investigate how CF patients respond to COVID-19

Event guide: 4th Extra-Hepatic Lipid-Based Nanoparticles Delivery Summit eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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